Data Sheet 3_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

Data Sheet 1_New prognostic features and personalized treatment strategies of mitochondrial related genes in colorectal cancer patients.docx حسب Qizheng Xu (21077153)

"…Key mitochondrial genes, including SUCLG2, ACACB, OSBPL1A, and TRAP1, have been identified as significant prognostic markers in CRC. The expression of ACACB and OSBPL1A progressively increased, while SUCLG2 and TRAP1 expression decreased in patients. …"

Table 2_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.docx حسب Haddad A. El Rabey (22248019)

"…The induced hypercholesterolemia significantly raised liver function enzymes, lipid peroxidation (14.9 ± 0.11 mg/dL), total cholesterol (273.3 ± 1.1 mg/dL), triglycerides (223.0 ± 4.1 mg/dL), low-density lipoproteins (204.7 ± 0.9 mg/dL), very low-density lipoproteins (44.6 ± 0.8 mg/dL), troponin, creatine kinase (CK), and adrenaline while decreased antioxidant enzymes, high-density lipoprotein (HDL), and vitamin D (11.1 ± 0.5 ng/mL). …"

Table 1_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx حسب Giacomo Brisca (10963929)

"…The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …"

Data Sheet 1_PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution.docx حسب Lin Zhang (8926)

"…Notably, we observed significant changes in immune cell populations, including reductions in macrophages (510 to 58 cells), NK cells (445 to 91 cells), and granulocytes (1597 to 1 cells). …"

Table 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

DataSheet2_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf حسب Maxim Sorokin (4379848)

"…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …"

Workflow of the study. حسب Hongliang Chen (538815)

"…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …"

Table 1_Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins.docx حسب Min Luo (258201)

"…Western blot analysis validated these findings in plasma samples, showing significantly increased expression of MMP12 and ASM, and decreased expression of NPNT and SNX1 in COPD patients compared to healthy controls, while KLC1 showed no significant difference. …"

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting? حسب Rafael Freitas (16738416)

"…</p><p dir="ltr"><b>Conclusions/Significance:</b> The density of In2Care stations varied across neighborhoods, ranging from 220 to 555 stations per km². …"

Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds حسب Wen Gu (129075)

"…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i>_E), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …"

Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease حسب Halil Onder (10368032)

"…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …"

Data_Sheet_1_Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study.docx حسب Chong Li (120471)

"…</p>Results<p>The BMI and 28-day mortality exhibited an L-shaped relationship (p for nonlinearity <0.001) with significant gender-specific differences. Subgroup analysis revealed different association patterns between the male and female cohorts. …"

Table 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx حسب Zhengqing Yu (12641890)

"…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…"

Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... حسب Yiran Wang (1492303)

"…</p> <p>A total of 53 RCTs with 126,232 participants were included. No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I² = 23%) in patients with SGLT-2i treatment compared with non-users. …"

Table 1_Trends in diet structural composition and quality among adults in Beijing, China (2010–2022).docx حسب Ningsu Chen (18014155)

"…Between 2010 and 2022, carbohydrate contribution to energy intake decreased from 56.1 to 46.7%, whereas fat intake increased from 31.6 to 36.9%. …"

Image3_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg حسب Saeko Yamada (11899439)

"…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…"

Effects of nano-curcumin on cell cycle and apoptosis in breast cancer cells. حسب Taraneh Givi (22793530)

"…The expression levels of <i>CCNA2</i> and <i>CCND1</i> were significantly decreased in both MCF7-S and MCF7-TR cells following nano-curcumin treatment. …"