Data Sheet 7_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 3_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif by Tengfei Tian (1793545)

“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”

<b>Collapsin response mediator protein 2 modulates synaptic function by stabilizing the surface expression of phosphorylated AMPA receptor GluA2 subunits</b> by ren (21408623)

“…Upon phorbol myristate acetate (TPA) induced activation of protein kinase C (PKC), the surface expression of GluA2 decreased significantly, as phosphorylation of GluA2 at the S880 site is known to promote its internalization. …”

Image 2_Integrating salpingoscopy and immunohistochemistry to improve tubal infertility diagnosis: a retrospective cohort study.jpeg by Adalyat Alenova (22696712)

“…</p>Results<p>Higher salpingoscopic severity scores were significantly associated with reduced pregnancy likelihood (r = −0.457; p < 0.0001). …”

Image 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg by Xiao-Ting Luo (20836646)

“…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…”

Data Sheet 9_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Data Sheet 4_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.csv by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Soil viral and microbial interactions facilitate microbial necromass carbon accumulation in the semiarid typical steppe under altered precipitation_Research Data by Cui Han (15263150)

“…The results showed that decreased precipitation significantly reduced microbial necromass carbon (BNC, MNC, and BNC/MNC) and their relative contributions to SOC (BNC/SOC and MNC/SOC), whereas increased precipitation had relatively weaker effects. …”

Image 1_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif by Tengfei Tian (1793545)

“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”

Data Sheet 1_α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach.docx by Aimin Cai (6190532)

“…</p>Results<p>The results of the study demonstrated that α-MT significantly reduced the urinary excretion of albumin and creatinine, improved kidney function, and decreased renal fibrosis in db/db mice. …”

Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents by Yujuan Li (554062)

“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”

Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Data Sheet 12_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…High MSCC scores correlated with poor prognosis, reduced immune cell infiltration, and decreased likelihood of benefiting from immune checkpoint inhibitor therapy. …”

Data Sheet 3_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.csv by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Bgh/GelMA/CMCS hydrogel with bone MSC-EVs for lunate defect repair by Miaozhong Li (21626739)

“…In vivo, the M1/M2 ratio and inflammatory factors decreased significantly one-week post-implantation, while CD31 and VEGF-positive cells increased at four weeks, and BMP2 and OPN-positive cells at eight weeks. …”

Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress by Serina Yan (22416354)

“…Peak calcium intensity was significantly reduced at 100 µM CBX, and both rise and fall rates of calcium signals decreased with increasing CBX concentration. …”

Data Sheet 9_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 2_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif by Tengfei Tian (1793545)

“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”

Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx by Shenglan He (7641308)

“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”