Data Sheet 1_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip by Ziqin Wei (19433134)

“…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …”

Data Sheet 6_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip by Ziqin Wei (19433134)

“…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …”

Data Sheet 7_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip by Ziqin Wei (19433134)

“…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …”

Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…Decreased CYP2J3 expression along with reduced PPAR-α levels, likely contributed to reduced anti-inflammatory EET levels, while elevated soluble epoxide hydrolase increased pro-inflammatory dihydroxyeicosatrienoic acids. …”

Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…Decreased CYP2J3 expression along with reduced PPAR-α levels, likely contributed to reduced anti-inflammatory EET levels, while elevated soluble epoxide hydrolase increased pro-inflammatory dihydroxyeicosatrienoic acids. …”

DataSheet1_Neuroprotective effect of Bouvardia ternifolia (Cav.) Schltdl via inhibition of TLR4/NF-κB, caspase-3/Bax/Bcl-2 pathways in ischemia/reperfusion injury in rats.PDF by Yury Maritza Zapata-Lopera (19725616)

“…</p>Conclusion<p>The dichloromethane extract of B. ternifolia demonstrated significant neuroprotective effects in the BCCAO/reperfusion model by modulating multiple signaling pathways. …”

Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc... by Muhammad Tahir (741682)

“…This research study is significant as it aims to assess the neuroprotective properties of vitamin E (VE) analog Trolox in an Aβ_{1 − 42}-induced AD mouse model. …”

Life Cycle Assessment to Quantify Global Warming and Human Health–Respiratory Impacts of Using Composites from Waste Wind Turbine Blades as Feedstock for Cement Clinker and Fibergl... by Caroline V. Cameron (22355207)

“…The increasing deployment of wind turbines also creates significant waste when turbine materials reach their end-of-life. …”

Table 1_Expression and diagnostic values of ferroptosis-related genes in coronavirus-associated viral sepsis.xlsx by Yidan Zhang (130332)

“…Functional enrichment analyses using GO and KEGG revealed significant enrichment in signaling pathways related to ferroptosis, oxidative stress, and HIF-1. …”

Image 1_Expression and diagnostic values of ferroptosis-related genes in coronavirus-associated viral sepsis.jpeg by Yidan Zhang (130332)

“…Functional enrichment analyses using GO and KEGG revealed significant enrichment in signaling pathways related to ferroptosis, oxidative stress, and HIF-1. …”

Ablation Experiment GradCAM Heatmap. by Chunhua Yang (346871)

“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”

Data Sheet 1_Biorefinery—inspired, two-step valorization strategy to manage plant-based recalcitrant organic waste, involving solvent extraction, and fermentation with Bacillus cla... by Sreejith Meppoyilam (20563139)

“…This novel two-step valorization workflow involves the extraction of small molecules using organic solvents, and fermentation of resulting denatured residues (increased biodegradability or decreased recalcitrance) of reduced microbial load. …”

Data Sheet 1_An autonomous navigation method for orchard mobile robots based on octree 3D point cloud optimization.docx by Hailong Li (216327)

“…The experimental results show that: 1) The overall number of point cloud data points in the map was reduced by approximately 76.32%, while important features, including tree morphology, trellis structure, and road surface information, were fully preserved. 2) When different octree node resolutions were applied, the improved RRT* algorithm demonstrated significant improvements in path generation time, sampling point utilization, path length, and curvature. …”

Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx by Maria Jordan (10265489)

“…</p>Results<p>Treatment with carvedilol reduced metabolic activity, inhibited cell proliferation, and led to decreased migratory activity, as observed in scratch wound assays, in human lung fibroblasts. …”

Space-to-depth convolution. by Chunhua Yang (346871)

“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”

Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…”

Data augmentation. by Chunhua Yang (346871)

“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”

Table 7_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Table 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…”

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Results<p>Treatment with carvedilol reduced metabolic activity, inhibited cell proliferation, and led to decreased migratory activity, as observed in scratch wound assays, in human lung fibroblasts. …”