Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx حسب Aierpati Moheteer (21522284)

"…Furthermore, the DSP nanoparticles-H group significantly decreased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TBIL), direct bilirubin (DBIL), and alkaline phosphatase (ALP). …"

Table 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc حسب Yaojin Sun (21692411)

"…Median bleeding episodes dropped from 3.00 to 0.00 (P < 0.001), indicating enhanced joint health and reduced bleeding frequency.</p>Conclusion<p>Regular prophylactic FVIII administration combined with individualized rehabilitation significantly reduces joint bleeding and enhances joint function and quality of life in children with hemophilia. …"

Data Sheet 1_Perilipin 5 alleviates ferroptosis of cardiomyocytes by targeting USP10-p53-TfR proteasome-dependent degradation.docx حسب Jianqiao Zhao (14519036)

"…In vivo experiments showed that overexpression of PLIN5 significantly reduced ferroptosis in the infarcted myocardium.…"

Data Sheet 2_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx حسب Yang Yu (4292)

"…TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …"

Table 1_Altered Th17/Treg balance and therapeutic targeting of RORγ in primary focal hyperhidrosis.docx حسب Min Lin (17652)

"…Sweat glands showed increased RORγt and decreased FOXP3 expression. In mice, SR2211 treatment reduced sweat secretion, secretory granules, and serum acetylcholine. …"

Data Sheet 1_The effect of prophylactic FVIII infusion combined with personalized rehabilitation on joint health and quality of life in children with hemophilia.doc حسب Yaojin Sun (21692411)

"…Median bleeding episodes dropped from 3.00 to 0.00 (P < 0.001), indicating enhanced joint health and reduced bleeding frequency.</p>Conclusion<p>Regular prophylactic FVIII administration combined with individualized rehabilitation significantly reduces joint bleeding and enhances joint function and quality of life in children with hemophilia. …"

Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function حسب Christiane S. Hampe (248347)

"…We recently studied effects of human monoclonal autoantibodies (mAb) derived from a pre-diabetic patient and demonstrated that a GAD65mAb penetrated and accumulated in beta cells and significantly reduced the insulin secretion rate (ISR). …"

Data Sheet 1_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx حسب Yang Yu (4292)

"…TaERF13-2B overexpression in Arabidopsis resulted in significantly reduced survival rates under drought conditions with decreased expression of stress-responsive and antioxidant enzyme genes, indicating that the TaERF13-2B gene elevated drought sensitivity in transgenic Arabidopsis. …"

Causal associations between kidney function and aortic valve stenosis: a bidirectional Mendelian randomization analysis حسب Wanqian Pan (18147420)

"…No significant causal relationship was found in reverse MR analysis.…"

Data Sheet 1_Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD.docx حسب Hyun-ju Lee (7550741)

"…</p>Results and discussion<p>In WT mice, hippocampal DYRK1A overexpression significantly reduced short-term spatial/recognition memory and SynGAP expression while increasing p-P38 levels. …"

Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx حسب Shenghua Lu (20762612)

"…Regarding intestinal barrier function, the BCP combination group significantly reduced diamine oxidase (MD = −0.69, 95% CI −0.87 to −0.50, p < 0.00001) and D-lactate (MD = −0.09, 95% CI −0.11 to −0.08, p < 0.00001). …"

Data Sheet 1_Physical study of the response of tidal flat development to the reduction in the input of Yellow River sediment into the sea.doc حسب Feng Yi (228659)

"…Offshore sediment concentration was decreased to simulate reduced sediment supply. An Argus system was deployed in the wave basin for the first time to capture the morphological changes during the experiment.…"

Image 2_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... حسب Xinchi Shang (11982840)

"…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …"

Image 3_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... حسب Xinchi Shang (11982840)

"…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …"

Table 1_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... حسب Xinchi Shang (11982840)

"…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …"

Image 4_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... حسب Xinchi Shang (11982840)

"…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …"

Image 1_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... حسب Xinchi Shang (11982840)

"…Cr(VI) stress significant increases in H₂O₂ and MDA levels and significant decreases in antioxidant enzyme activity levels (SOD, GSH-Px, and T-AOC) and energy metabolism-related ATPase activity levels (Na⁺K⁺-ATPase, Ca²⁺-ATPase, and Mg²⁺-ATPase). …"

Data Sheet 1_Application of compost amended with biochar on the distribution of antibiotic resistance genes in a soil–cucumber system—from the perspective of high-dose fertilizatio... حسب Shuai Shi (333614)

"…Compost application to soils significantly decreased ARG abundance in cucumbers; SBTC had the most significant effect and reduced the number of host bacteria at the phylum level from four to three. …"

Supplementary file 1_Assessing pteropod shell dissolution to advance ocean monitoring techniques: a methods comparison of SEM, CT, and light microscopy.zip حسب Bryce E. Koester (21473132)

"…<p>Pteropods are marine planktonic snails that are used as bioindicators of ocean acidification due to their thin, aragonitic shells, and ubiquity throughout the world’s oceans; their responses include decreased size, reduced shell thickness, and increased shell dissolution. …"

Image 4_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif حسب Si-Ting Huang (5591432)

"…Inhibition of TRPA1 or administration of recombinant IL-18 significantly reduced DNFB-induced itch behavior in Nlrp3-/- mice. …"