بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
reduced decrease » reduced disease (توسيع البحث), reported decrease (توسيع البحث), induces decreased (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
reduced decrease » reduced disease (توسيع البحث), reported decrease (توسيع البحث), induces decreased (توسيع البحث)
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5901
Table 3_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
منشور في 2025"…Additionally, β-catenin knockdown led to an upregulation of CASP7 expression, whereas activation of the Wnt/β-catenin signaling pathway reduced CASP7 protein levels. ZZF decreases the activity of the Wnt/β-catenin signaling pathway by decreasing β-catenin transcription and nuclear localization.…"
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5902
In Vivo, In Vitro, and In Silico Assessment of Anticancer Activity of the New Pincer-Type Pt(II) Complexes
منشور في 2025"…The in vivo findings reinforced these results, demonstrating that <b>Pt1</b> significantly reduced tumor growth while exhibiting minimal systemic toxicity. …"
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5903
DataSheet1_Diphenyl diselenide protects against diabetic kidney disease through modulating gut microbiota dysbiosis in streptozotocin-induced diabetic rats.docx
منشور في 2024"…Furthermore, DPDS intervention markedly reduced the protein expression of α-SMA, COI Ⅳ, FN, and vimentin in the kidneys. …"
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5904
Image1_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
منشور في 2024"…Here, using surface biotinylation and (N-(Ethoxycarbonylmethyl)-6-Methoxyquinolinium Bromide) MQAE-dye based fluorescence quenching, we show that upregulated GABA<sub>A</sub>R are on the cell-surface in TNBC cell lines and mediate significantly higher chloride (Cl<sup>−</sup>) flux as compared to non-tumorigenic MCF10A cells. …"
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5905
Table 2_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx
منشور في 2025"…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …"
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5906
The components of Qili Qiangxin capsule.
منشور في 2024"…QLQX treatment for 28 days significantly improved cardiac function, as evidenced by decreases in heart mass index, cardiac volume, left ventricular end-diastolic diameter, left ventricular end-systolic diameter, N-terminal B-type natriuretic peptide levels, and high-sensitivity cardiac troponin I levels and increases in left ventricular ejection fraction and left ventricular fraction shortening. …"
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5907
Image 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
منشور في 2025"…Additionally, β-catenin knockdown led to an upregulation of CASP7 expression, whereas activation of the Wnt/β-catenin signaling pathway reduced CASP7 protein levels. ZZF decreases the activity of the Wnt/β-catenin signaling pathway by decreasing β-catenin transcription and nuclear localization.…"
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5908
Table 2_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
منشور في 2025"…Additionally, β-catenin knockdown led to an upregulation of CASP7 expression, whereas activation of the Wnt/β-catenin signaling pathway reduced CASP7 protein levels. ZZF decreases the activity of the Wnt/β-catenin signaling pathway by decreasing β-catenin transcription and nuclear localization.…"
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5909
Table 1_Exploring the therapeutic potential of “Zhi-Zhen” formula for oxaliplatin resistance in colorectal cancer: an integrated study combining UPLC-QTOF-MS/MS, bioinformatics, ne...
منشور في 2025"…Additionally, β-catenin knockdown led to an upregulation of CASP7 expression, whereas activation of the Wnt/β-catenin signaling pathway reduced CASP7 protein levels. ZZF decreases the activity of the Wnt/β-catenin signaling pathway by decreasing β-catenin transcription and nuclear localization.…"
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5910
Table 1_Effects of compound lactic acid bacteria on the quality and microbial diversity of alfalfa silage in saline-alkali soils.xlsx
منشور في 2025"…The results of the microbial community showed that compared with the non-additives group, the Shannon index decreased and the Simpson index increased in the compound lactic acid bacteria group, indicating a significant reduction in microbial diversity in the silage environment (P < 0.05). …"
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5911
Data Sheet 1_Effects of compound lactic acid bacteria on the quality and microbial diversity of alfalfa silage in saline-alkali soils.zip
منشور في 2025"…The results of the microbial community showed that compared with the non-additives group, the Shannon index decreased and the Simpson index increased in the compound lactic acid bacteria group, indicating a significant reduction in microbial diversity in the silage environment (P < 0.05). …"
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5912
Table 2_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc
منشور في 2025"…Severe cases may necessitate a reduced PLD dose or even delay or interrupt chemotherapy, ultimately leading to decreased medication compliance. …"
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5913
Table 4_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.xlsx
منشور في 2025"…In this study, the seed germination rate and seedling growth were reduced in the tomato slerf4-9 mutant. The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. …"
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5914
Table 5_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.xlsx
منشور في 2025"…In this study, the seed germination rate and seedling growth were reduced in the tomato slerf4-9 mutant. The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. …"
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5915
Table 3_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.xlsx
منشور في 2025"…In this study, the seed germination rate and seedling growth were reduced in the tomato slerf4-9 mutant. The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. …"
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5916
Image 1_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.jpeg
منشور في 2025"…In this study, the seed germination rate and seedling growth were reduced in the tomato slerf4-9 mutant. The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. …"
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5917
Data Sheet 1_Immune monitoring of trabectedin therapy in refractory soft tissue sarcoma patients - the IMMUNYON study.pdf
منشور في 2025"…PD patients showed reduced eosinophils (p<0.05) and Th2 cells (p<0.05). …"
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5918
Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
منشور في 2025"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"
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5919
Image 2_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.jpeg
منشور في 2025"…In this study, the seed germination rate and seedling growth were reduced in the tomato slerf4-9 mutant. The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. …"
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5920
Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
منشور في 2025"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"