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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
reduced decrease » reduced disease (Expand Search), reported decrease (Expand Search), induces decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
reduced decrease » reduced disease (Expand Search), reported decrease (Expand Search), induces decreased (Expand Search)
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6581
Table 1_To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux.docx
Published 2025“…</p>Results<p>Ruanjian Qingmai granules significantly decreased lipid deposition and significantly increased the expression of CYP7A1 mRNA in both zebrafish and HepaRG cells. …”
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6582
Data Sheet 1_Boundary currents in the Bransfield Strait: near-surface interbasin water volume and heat exchange.pdf
Published 2025“…Heat transport analyses reveal significant asymmetries: the Bransfield Current contributes up to 5.44x10<sup>12</sup> W eastward in summer based on a hydrographic climatology constructed from CTD, MEOP, and Argo float measurements (0–100 m depth) and 6.67x10<sup>11</sup> W using remotely-sensed sea surface temperature (0–10 m depth). …”
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6583
Supplementary Material for: Adverse Prognosis in Membranous Nephropathy with PLA2R1 Epitope Spreading: A Prospective Study
Published 2025“…Results: All patients had anti-CysR antibodies. 26(50.0%) exhibited multi-domain recognition, with one patient specifically recognizing the CTLD8 domain. A significant association was observed between PLA2R1-Ab and CysR-Ab(r = 0.869, P <0.001), as well as with anti-CTLD1 antibody(r = 0.803, P <0.001). …”
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6584
Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6585
Table 1_Study on Chaiyuwendan decoction’s inhibition of hippocampal neuron apoptosis to alleviating depression by activating the AKT/CREB pathway.docx
Published 2025“…The in vivo studies showed that CYWD treatment improved mice’ depression-associated behaviors, decreased 5-HT, DA and NE while increased ACTH, reduced hippocampal neuronal damage. …”
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6586
Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6587
Video 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6588
Data Sheet 1_Therapeutic efficacy of a galactoglucan from Pleurotus citrinopileatus in constipation: modulation of aquaporin signaling and intestinal barrier.pdf
Published 2025“…The oral administration of PCP-g resulted in a significant reduction in constipation symptoms, as indicated by an increase in fecal water content, normalization of pellet formation, enhancement of total fecal mass, decreased latency to the first stool, and improved intestinal propulsion. …”
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6589
Data Sheet 1_The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathog...
Published 2025“…Furthermore, the structures of the kidney, spleen, and intestinal tissues were intact, and the expression of p53 and γH2A.X decreased in the kidney.</p>Conclusion<p>L-PA-IgY and I-PA-IgY can resist multiple bacterial infections and have immunoprotective effects with no significant differences. …”
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6590
Data_Sheet_1_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx
Published 2024“…Sensitivity analysis after excluding outlier study, yielded a pooled odds ratio of 0.19 (95% CI: 0.02 to 1.52) with reduced heterogeneity (I<sup>2</sup> = 63%). Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”
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6591
Supplementary materials for PhD thesis - "Understanding ⁴⁰Ar/³⁹Ar age variations in basaltic lavas"
Published 2025“…However, even after the evaluation of <sup>40</sup>Ar/<sup>39</sup>Ar age reliability, significant inter-lava age variations are still observed and which have been related to inter-lava variations in geochemistry, loss on ignition values and other alteration indices. …”
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6592
Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6593
Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx
Published 2025“…Compared with the control group, the mRNA expressions of glutathione peroxidase (GSH-Px), NAD(P)H quinone dehydrogenase 1 (NQO1), catalase (CAT), nuclear factor erythroid 2-related factor 2 (Nrf2), transferrin receptor protein 1 (TFR1), and ferritin heavy chain 1 (FTH1) in the breast muscle were decreased (p < 0.05). The addition of QG to the diet reduced the levels of ROS and oxidation products (p < 0.05). …”
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6594
Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6595
Data_Sheet_2_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx
Published 2024“…Sensitivity analysis after excluding outlier study, yielded a pooled odds ratio of 0.19 (95% CI: 0.02 to 1.52) with reduced heterogeneity (I<sup>2</sup> = 63%). Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”
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6596
Supplementary Material: Spent hemp biomass as a feed ingredient for beef steers: effects on performance, blood parameters, behavior, cannabinoid residues, and consumer exposure lev...
Published 2025“…The steers fed SHB had higher feed intake than CON animals, indicating no palatability issue with SHB, but their feed efficiency was decreased. Consuming SHB enhanced ruminal acetate production and reduced the propionate proportion. …”
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6597
Supplementary file 1_Negative associations between macronutrient quality index and lung cancer incidence and mortality: results from the prostate, lung, colorectal, and ovarian can...
Published 2025“…Our results demonstrate a distinct, statistically significant inverse association between a higher MQI and both a reduced incidence (HR Q4 vs. …”
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6598
Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6599
Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”
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6600
Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”