Mitigation of Senescence Burden in Doxorubicin-Induced Senescent Endothelial Cells by MitoQ Treatment Through Diminishing Mitochondrial ROS and DNA Damage. by Hossein Abdeahad (22177792)

“…DOXO increased mtROS, decreased mitochondrial mass, and induced senescence. …”

Data Sheet 2_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.docx by Shiyan Wang (1594996)

“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”

Data Sheet 1_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.zip by Shiyan Wang (1594996)

“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”

Table 2_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Image 1_Ruminococcus bromii-generated acetate alleviated Clonorchis sinensis-induced liver fibrosis in mice.jpeg by Chun Li (57810)

“…</p>Results<p>The abundance of R. bromii increased during the inflammatory stage of C. sinensis infection and decreased significantly during the fibrosis stage. …”

Table 4_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 5_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 1_Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.docx by Yi-Ting Sun (4691629)

“…</p>Results<p>At 6 months, the median (IQR) VAS score significantly decreased from 66.5 (27) to 24 (34) (95% CI = −38 to −30.5), p < 0.001), and WOMAC scores improved from 29 (22) to 12 (14) (95% CI = −16.5 to −12), p < 0.001). …”

Table 1_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

Table 3_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…</p>Results<p>The body weight of COPD mice was significantly lower than that of Muscone-treated COPD mice, consistent with decreased lung function, accompanied by reduced circulating and lung IL-38 levels. …”

<b>Metabolic Perturbations and Ectopic Fat Deposition in Low Birthweight Subjects</b><b>– Effects of a 4 Week Carbohydrate Overfeeding Challenge</b> by Charlotte Brøns (261017)

“…Subcutaneous adipose tissue (SAT) density was lower in LBW subjects and decreased during COF in both groups. Serum alanine, phosphatidylcholines, and triglycerides increased significantly more in LBW subjects during COF. …”

<b>Chemical components, emission dynamics, and external immune functions of red palm weevil larval volatiles in response to changes in developmental stages and pathogen stress</b> by Can-Hui Ding (22140753)

“…Furthermore, pathogen stress induced distinct volatile profiles: phenylacetaldehyde unidirectionally decreased, whereas <i>n</i>-nonanol, 4-ethylguaiacol, 2-phenylethanol, hexanal, and benzophenone levels increased. …”

Data Sheet 1_Integrated transcriptome and co-expression network analysis revealed the molecular mechanism of cold tolerance in japonica rice at booting stage.zip by Jiaqi Wang (369548)

“…</p>Results<p>The results demonstrated that cold stress significantly decreased yield traits, particularly seed-setting rate—a reliable cold tolerance indicator. …”

Effect of inhibitors on model parameters as inferred by SBI. by Johannes C. J. Heyn (21567894)

“…(a) Latrunculin A significantly decreases the actin network extension rate V_e⁰ for both MDA-MB-231 and MCF-10A cells while leaving all other parameters unchanged. …”

ZIKV infection enriches the HLA Class I pathway in brain tumour cells. by Matt Sherwood (22530221)

“…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …”

The expression of PAX7 and MYOD1 correlate with differential expression of diverse chemokines in HuMuSC. by Katharine Striedinger (15503387)

“…Using linear regression PAX7 slope varies significantly p = 0.0001 and MYOD1 slope also varies significantly p = 0.05 n = 3 <b>(b)</b> Heat map displaying the expression levels of all cytokine protein detected in HuMuSC from collection as they activate progressively at day 0, day 3 and day 6 <i>in vitro</i>, using the high throughput proteomic Multiplex assay. …”

Table 1_Engineered miR-214 enriched Schwann cell-derived extracellular vesicles amplify therapeutic efficacy for peripheral neuropathy in T2D mice.docx by Lei Wang (6656)

“…Furthermore, 214-EVs markedly suppressed neuroinflammation by decreasing CD68 + macrophages and inactivating the TLR4/NF-κB signaling pathway. …”

Data Sheet 1_Impact of SARS-CoV-2 vaccination and of seasonal variations on the innate immune inflammatory response.pdf by Hend Jarras (13138641)

“…</p>Results<p>Our results show that IL-8 production after stimulation decreased after vaccination. In addition, the IL-8 response was significantly different depending on the season when the visit occurred, for both COVID-19 vaccinated and unvaccinated individuals.…”

Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”