Data Sheet 7_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip by Zeng Zhang (299463)

“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”

Data Sheet 4_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip by Zeng Zhang (299463)

“…Within the IG group, IL-6, JAK2, STAT3, and IL-1β proteins were significantly elevated compared to the HC group, whereas STAT1, p-JAK2, and p-STAT1/3 proteins were significantly lower. …”

Table 1_Effects of Raga music and Chinese five-element on milk production, antioxidant, neuroendocrine, immune, and welfare indicators in dairy cows.docx by Zongjing Cao (21622439)

“…Dairy cows in the music intervention groups displayed significant improvements in serum biochemical parameters, characterized by decreased levels of alanine aminotransferase (ALT) and triglycerides (TG) (p < 0.05), and increased concentrations of glucose (GLU) and serum albumin (ALB) (p < 0.05). …”

Data Sheet 1_Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.pdf by Irina A. Strigo (9745472)

“…</p>Results<p>MyP led to significant decreases in PEG scores overall. Furthermore, MyP responders exhibited increased pain-related activation in key brain regions, including the contralateral posterior insula, bilateral ventral anterior insula, ventral anterior cingulate, dorsolateral prefrontal cortex, and nucleus accumbens. …”

Data Sheet 1_Age and growth of Todaropsis eblanae (Ommastrephidae) through comparison of statoliths, beaks and eye lenses.docx by Blondine Agus (10990749)

“…Moreover, the Mann-Whitney W-test confirmed a highly significant relationship between the number of growth increments in beaks and statoliths, suggesting that the beak can be considered a valid alternative to statoliths for age estimation in T. eblanae. …”

Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx by Yidi Ma (9507153)

“…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …”

Data Sheet 1_Global, regional, and national burden and trends of intracerebral hemorrhage among adolescents and young adults aged 15–39 years from 1990 to 2021: a comprehensive tre... by Xuanchen Liu (12188147)

“…Background<p>Intracerebral hemorrhage (ICH) poses a significant health challenge, notably affecting adolescents and young adults (AYAs) aged 15–39 years. …”

Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx by Hailiang Li (740080)

“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”

DataSheet1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.doc by Guojun Lu (7169969)

“…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …”

Table1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.docx by Guojun Lu (7169969)

“…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …”

Data Sheet 1_Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study.xlsx by Jiayun Ling (15249289)

“…Notably, C3 remained significantly correlated at week 48 (r = 0.513, P = 0.025). …”

Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma by Marianna Carrabotta (8193039)

“…<b>A,</b> Inhibition of PDX-CDS #4-C tumor growth after treatments with trabectedin and/or NVP-BEZ235. Significant reduction in tumor growth was observed after single treatments (*, <i>P</i> < 0.05, Student <i>t</i> test) but the inhibition increased after combination of the two drugs (significance was at least ***, <i>P</i> < 0.001, Student <i>t</i> test starting from day 23) or to single treatments (*, <i>P</i> < 0.05). …”

Table 1_Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort.docx by Mary Ngongang Kameni (20924126)

“…Our most significant findings include the association of double mutant alleles (AA) of rs4646140 and rs2074192 in the ace2 gene with decreased IL-6 and IL-2 expression levels respectively in TB-COVID-19 participants. …”

Table 1_Effectiveness of Mindfulness and Qigong Training for Self-Healing in patients with Hwabyung and depressive disorder: a randomized controlled trial.docx by Seok-In Yoon (13879160)

“…Only one adverse event was reported during the intervention period. Home practice was not significantly associated with any intervention change.…”

Image 1_Effectiveness of Mindfulness and Qigong Training for Self-Healing in patients with Hwabyung and depressive disorder: a randomized controlled trial.tif by Seok-In Yoon (13879160)

“…Only one adverse event was reported during the intervention period. Home practice was not significantly associated with any intervention change.…”

Supplementary Material for: Impact of Liraglutide 3.0 mg on Metabolic Dysfunction-Associated Steatotic Liver Disease in Individuals with Obesity: A Real-World Study by figshare admin karger (2628495)

“…Hepatic steatosis index (HSI) and non-alcoholic fatty liver disease (NAFLD) liver fat score also decreased significantly (HSI: 44.7 ± 6.2 to 42.2 ± 5.8 p<0.001; NAFLD liver fat score: 2.12 ± 2.90 to 0.43 ± 1.91, p<0.001). …”

Rinderine suppresses African swine fever virus replication in porcine alveolar macrophages by dual targeting of membrane-associated profilin 1 and phosphatidylethanolamine by Di Liu (30843)

“…Natural small molecules have been reported to exhibit anti-ASFV potential. This study utilized the previously established high-throughput platform for screening ASFV inhibitors to identify rinderine (RIN), a pyrrolizidine alkaloid that not only significantly inhibits ASFV replication but also maintains sustained anti-ASFV activity at 24, 48, and 72 hours postinfection. …”

Data Sheet 1_The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study.pdf by Rong Tian (397491)

“…</p>Conclusion<p>Frail individuals exhibit poorer performance in peripheral and central hearing assessments, as well as in self-reported hearing handicap. Future randomised controlled trials are necessary to find out if the correction of hearing loss decreases the proportion of people affected by frailty in later life.…”

Supplementary Material for: Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration by Rouse M. (20413172)

“…Paired t-tests identified 25 additional analytes that showed significant decreases (p<0.05) only without Bonferroni correction. …”

Data for journal article: Stability of electrodeposited manganese oxide films under electrochemical carbon dioxide reduction conditions by Katherine Holt (6766220)

“…Given that such Mn oxide materials have been reported as successful CO₂ reduction electrocatalysts under identical conditions, this result was unexpected, but could be explained by a decreased kinetic stability of the electrodeposited film compared to Mn oxide materials prepared by other methods. …”