MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway by Jing Liu (38537)

“…</p> <p>ATP binding cassette transporter 1 (ABCB1) had the highest mutation frequency and multiple mutation types in HNSCC, and the decreased ABCB1 was significantly related to better prognosis of HNSCC patients. …”

Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Table4_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Supplementary Material for: Diverse Obesity Trajectories in a Family including Identical Twins with a Pathogenic MC4R Variant by figshare admin karger (2628495)

“…Twin 2 had a sedentary lifestyle and epilepsy and had a peak BMI of 30.1 kg/m2; she responded well to naltrexone-bupropion and BMI decreased to 26 kg/m2. Conclusion: The manifestation of obesity, even in cases of monogenic obesity, can vary significantly due to the influence of environmental and lifestyle factors.…”

<b>Selective Reduction of Ca</b>^{<strong>2+</strong>}<b>-Independent Phospholipase A</b>_{<strong>2</strong>}<b>b</b><b> (iPLA</b>_{<strong>2</strong>}<b>b... by Abdulaziz Almutairi (9584768)

“…These outcomes are associated with a significant reduction in T1D. Further, inhibition of select proinflammatory lipid signaling pathways reduces M1-like MF polarization and adoptive transfer of M2-like MF reduces NOD T1D incidence, suggesting a mechanism by which iDLs impact T1D development. …”

Image 1_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Table 1_Spatial stratified heterogeneity of mumps incidence in China: a Geodetector-based analysis of driving factors.xlsx by Ke Hu (84619)

“…</p>Results<p>The findings revealed a distinct west-to-east decreasing trend of mumps incidence in China, demonstrating significant spatial autocorrelation primarily manifested as high-high clustering in western areas and low-low clustering in eastern regions. …”

Table 2_IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis.docx by Jing Chen (4762)

“…Significantly increased expression of miR-106b-3p and decreased expression of HBsAg and HBV DNA were observed in Huh7-C2/B3 cells treated with IFN-exo. …”

Supplementary Material for: Efficacy and safety of transdermal medical cannabis (THC:CBD: CBN formula) to treat painful diabetic peripheral neuropathy of the lower extremities by Seevathee K. (20196534)

“…GEE analysis revealed significant pain amelioration at weeks 4, 8, and 12 (p<0.001). …”

Supplementary data.xlsx by Danjun Li (21443051)

“…Sirt6 is a NAD+-dependent epigenetic regulator that has recently been found to play an important role in maintaining telomere stability. Here, we report for the first time that NAD+ levels are significantly lower in blastocysts cultured in vitro than that in blastocysts developed in vivo, leading to impaired Sirt6 function, further triggering telomere shortening of the inner cell mass and possibly affecting newborn offspring. …”

Table 1_Antiepileptic drugs and foetal disorders: analysis of 20-year data from the pharmacovigilance center.docx by Zejun Ji (20787176)

“…The risk of foetal disorders associated with combination therapies varied depending on the specific AEDs combination, with some increasing and others decreasing the risk compared to monotherapy.</p>Conclusion<p>The analysis of the reports from FAERS database identified correlation between foetal disorders and AEDs and provided a comprehensive overview of the incidence and prognosis of different AEDs monotherapy and combination, which may provide some advice for the selection of drug for women of childbearing age.…”

Table 1_Prevalence and prognostic value of sarcopenia in patients with bladder cancer undergoing radical cystectomy: a systematic review and meta-analysis.docx by Lei Zhang (38117)

“…</p>Objectives<p>This study was conducted to systematically evaluate the prognostic significance of sarcopenia in patients with bladder cancer undergoing RC.…”

Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Ambient Air Pollutant Dynamics (2010–2025) and the Exceptional Winter 2016–17 Pollution Episode: Implications for a Uranium/Arsenic Exposure Event by Thomas Clemens Carmine (19756929)

“…</li><li><b>Long-Term Trends:</b> The complete time series reveals significant downward trends in NO₂, EC, and SO₂ over the ~15-year period. …”

Table1_Characterization of morphological and chemical changes using atomic force microscopy and metabolism assays: the relationship between surface wax and skin greasiness in apple... by Yanqing Yang (1698535)

“…</p>Results<p>AFM results revealed that wax crystals disappeared as skin greasiness increased, accompanied by significant declines in roughness parameters Ra, Rq, Rmax, and Rz, which decreased by 70% to 85%. …”

community_experiment_and_pure_culture.xlsx by Wen-Wen Huang (22122439)

“…In both experiments, PE and PVC significantly reduced viral abundances. However, their effects on bacterial abundances were context-dependent. …”