Data Sheet 1_A ROS-responsive, aptamer-targeted graphene oxide nanocomposite for site-specific glutathione release in cerebral ischemia-reperfusion injury.docx by Meiying Li (6051287)

“…In vitro, GO@GSH-FA significantly restored viability in oxygen-glucose-deprived SH-SY5Y cells (from 31% up to near control levels), reduced inflammatory cytokines, and lowered intracellular ROS. …”

Table 1_Effect of dietary supplementation with aspirin eugenol ester on performance and ileum health in broilers under high stocking density stress conditions.docx by Penghui Ma (11925805)

“…Dietary addition of AEE significantly increased body weight gain and improved antioxidant capacity with restoration of intestinal morphology in broilers with HDS. …”

Data Sheet 1_Efficacy of hemoadsorption in the severe course of COVID-19.docx by Aleksei Yurievitch Yakovlev (20837198)

“…</p>Results<p>This observational study revealed the capability of Efferon CT hemoadsorption to safely, rapidly, and significantly reduce the need for norepinephrine, increase the oxygenation index, prevent the sepsis-associated AKI, decrease the development of multiorgan failure, and restore the immune system balance by decreasing pro-inflammatory IL-6, ferritin levels, and neutrophil-to-lymphocyte ratio.…”

Supplementary file 2_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.docx by Yasuhiro Shimojima (4615840)

“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”

Supplementary file 1_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.pptx by Yasuhiro Shimojima (4615840)

“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”

Data_Sheet_1_Synergistic co-evolution of rhizosphere bacteria in response to acidification amelioration strategies: impacts on the alleviation of tobacco wilt and underlying mechan... by Zhang Bian-hong (19768686)

“…The key factors controlling wilt were identified through random forest regression analysis as an increase in soil pH and exchangeable bases, along with a decrease in exchangeable acidity. However, lime treatment alone led to an increase in soil bulk density and a decrease in available nutrients, whereas both biochar and lime-biochar treatments significantly improved these parameters (p < 0.05). …”

Data Sheet 1_Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells.pdf by Mariia Stefanenko (16987420)

“…Pharmacological inhibition of GSL synthesis with eliglustat significantly reduced HexCers levels and restored ER Ca²⁺ stores, but did not impact cytokine-induced cytokine/chemokine secretion or cell viability/proliferation.…”

OMT by Jingmin Ou (19669426)

“…MTS cell viability assay showed that overexpression of SIRT1 partially restored the decrease in cell viability due to the interference with HIF-1α. …”

Image 4_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Image 2_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Image 1_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Table 3_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.docx by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Table 2_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.xlsx by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Table 1_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.xlsx by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Image 5_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Image 3_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…</p>Results<p>The findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”

Supplementary file 2_Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.docx by Ziao Liu (8938748)

“…Mechanistic investigations revealed that WZYZW markedly suppressed germ cell apoptosis (flow cytometry confirmed a significant decrease in apoptotic cell proportion) and attenuated DNA damage (indicated by significantly reduced γ-H2AX (a DNA damage marker) fluorescence intensity). …”

Table 1_Enhancement of oxaliplatin efficacy and amelioration of intestinal epithelial damage by Lactobacillus rhamnosus GG through modulation of gut microbiota.xlsx by Zijie Zhang (2543533)

“…</p>Results<p>The combined treatment of LGG and Oxp significantly reduced tumor weight and volume, and improved tumor-associated pathological changes compared to the model group. …”

Data Sheet 1_Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity.docx by Krishma Tailor (13730582)

“…In this model, once-daily injections of CV1574-1 for 5 days partially restored the pegvisomant-induced decrease in growth plate height without increasing kidney cell proliferation. …”

Image 4_CXCR7-TAGLN2 protein complex regulates invasion and metastasis in papillary thyroid carcinoma: a potential therapeutic target.tif by Chao Zeng (452370)

“…Objective<p>To investigate the expression and clinical significance of CXCR7 and TAGLN2 in papillary thyroid carcinoma (PTC), and to explore the molecular mechanisms underlying the interaction between CXCR7 and TAGLN2 in regulating PTC invasion and metastasis.…”