Image 2_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. Post-treatment, liver enzymes decreased, inflammatory scores improved, and type I interferon pathways were restored, yet 14 of 17 patients (82.3%, 95% CI: 64.2–100%) retained persistent lymphocytic infiltrates. …”

Image 1_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. Post-treatment, liver enzymes decreased, inflammatory scores improved, and type I interferon pathways were restored, yet 14 of 17 patients (82.3%, 95% CI: 64.2–100%) retained persistent lymphocytic infiltrates. …”

Image 5_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. Post-treatment, liver enzymes decreased, inflammatory scores improved, and type I interferon pathways were restored, yet 14 of 17 patients (82.3%, 95% CI: 64.2–100%) retained persistent lymphocytic infiltrates. …”

Table 1_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.docx by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. Post-treatment, liver enzymes decreased, inflammatory scores improved, and type I interferon pathways were restored, yet 14 of 17 patients (82.3%, 95% CI: 64.2–100%) retained persistent lymphocytic infiltrates. …”

Image 3_Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.tif by Daniel E. Millian (20296458)

“…Baseline modified hepatitis activity index (MHAI) scores (OR = 1.90, 95% CI: 0.72–6.34) and fibrosis stage (OR = 1.65, 95% CI: 0.44–9.97) trended toward predicting poor outcomes but were not significant. Post-treatment, liver enzymes decreased, inflammatory scores improved, and type I interferon pathways were restored, yet 14 of 17 patients (82.3%, 95% CI: 64.2–100%) retained persistent lymphocytic infiltrates. …”

Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx by Fahad Mubariz (16010003)

“…Increased mTORC1 activity resulted in excess TFEB phosphorylation and decreased nuclear translocation. Pharmacological mTOR inhibition restored TFEB activity, decreased ER stress and reduced α-synuclein accumulation, indicating improvement of neuronal protiostasis. …”

Data Sheet 1_Real-life data on pasireotide in monotherapy or combined in active Cushing’s disease.pdf by Alessandro Mondin (22611146)

“…Cholesterol levels tended to decrease, and a significant weight loss was observed (>5% in 47% of cases). …”

Supplementary Material for: Spontaneous Massive Retroperitoneal Hematoma: A Rare Complication of Anticoagulation after Stenting in Malignant Superior Vena Cava Syndrome by figshare admin karger (2628495)

“…After the procedure, she was on prophylactic low-molecular-weight heparin and developed a large retroperitoneal hematoma with a significant decrease in haemoglobin on day four. The patient was managed with a transfusion and conservative care. …”

<i>NDUFS7</i> depletion in motor neurons affects synapse stability. by Bhagaban Mallik (12459375)

“…Futsch-positive loops were significantly restored to the control number when <i>NDUFS7[RNAi]</i> knockdown larvae were raised in media containing NACA or when genetically expressing <i>UAS-Sod2</i> in the <i>UAS-<i>NDUFS7[RNAi]</i></i> knockdown background. …”

<b>L-Tryptophan as a Frontier in Diabetes Management: A Pilot Study</b> by dr.gayathri M rao (22045067)

“…</p><p dir="ltr">A significant decrease in the glucose absorption and blood glucose level in the tryptophan treated diabetic group in comparison with diabetic controls. …”

Data Sheet 1_Decadal changes in species composition of rare oak Quercus chungii forests with logging history.docx by Wenbin Li (92586)

“…A larger contribution from balanced abundance variations than abundance gradient to the temporal β diversity suggested that there was no significant consistent increase or decrease in species abundance during this decade. …”

Supplementary file 1_Wetland degradation promotes soil P fraction transformation by altering P-cycling functional genes and metabolic pathways.docx by Yumeng Jiang (13036113)

“…Our results show that total inorganic P content decreased significantly with increasing degradation intensity. …”

Supplementary material by Everton Tizo-Pedroso (14380182)

“…The results indicated variations in geographical and economic patterns across the Serra, Formiga, and Mata micro-basins. There was a significant increase in pasture, cultivation, and urban activities in the predicted scenarios, leading to a reduction in forest cover and water bodies. …”

Supplementary file 1_Catalpol—a compound from Rehmannia glutinosa can improve hyperlipidemia by modulating gut microbiota and endogenous metabolic pathways.zip by Xinfeng Pei (22597664)

“…The 16S rRNA sequencing results showed that the consumption of an HFD led to a significant increase in the abundance of Firmicutes and a decrease in that of Bacteroidetes. …”

Supplementary file 1_Distance and orientation of hydrophones influence the received soundscape in shallow coral reefs.docx by Juan Carlos Azofeifa-Solano (10983207)

“…</p>Discussion<p>These findings indicate that sensor directivity significantly influences the received soundscape, introducing a potential methodological bias within and across acoustic datasets. …”

Data supporting "Skin Effect Induced Anomalous Dynamics from Charge-Fluctuating Initial States" by Sibo Guo (21313436)

“…<p dir="ltr">Non-equilibrium dynamics in non-Hermitian systems has attracted significant interest, particularly due to the skin effect and its associated anomalous phenomena. …”

Table 5_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Table 2_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Table 1_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”

Image 1_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…Furthermore, PA treatment attenuated intestinal dysbiosis in UC mice, characterized by an increase in beneficial bacteria (e.g., Psychrobacter) and a decrease in taxa like Actinobacteriota.</p>Conclusion<p>These findings collectively indicate that the aqueous extract of Periplaneta americana L. and its fractions possess significant therapeutic potential for UC treatment, with the unfractionated extract showing the most pronounced benefits via modulating inflammation, restoring barrier function, and rebalancing gut microbiota.…”