Image 1_Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation.png by Xing Han (802860)

“…The diameter and number of cancerous foci were significantly decreased in CRC mice treated with FMT, along with the restoration of the intestinal mucosal structure and the lessening of the gland arrangement disorder. …”

Table 1_Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantation.docx by Xing Han (802860)

“…The diameter and number of cancerous foci were significantly decreased in CRC mice treated with FMT, along with the restoration of the intestinal mucosal structure and the lessening of the gland arrangement disorder. …”

Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx by Ji Yang (114503)

“…</p>Results<p>Oral administration of Lumefantrine significantly attenuated disease activity index (DAI) scores and restored intestinal barrier integrity through upregulation of epithelial tight junction proteins Claudin-1 and ZO-1. …”

In sepsis-associated cardiotoxicity, remifentanil reduces oxidative stress, inflammation, and apoptosis to maintain mitochondrial biogenesis by inhibiting NFkB and Cas-3 immunoexpr... by Muhammet Yusuf TEPEBAŞI (22576416)

“…</p> <p>REMI exhibits significant cardioprotective effects in LPS-induced SIC by attenuating inflammation, oxidative stress, and apoptosis while preserving mitochondrial homeostasis.…”

Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS by Long Ma (133810)

“…However, intervention with molecular hydrogen significantly mitigated this damage. Specifically, molecular hydrogen reduced the production of ROS and restored mitochondrial function, thereby alleviating oxidative stress and apoptosis. …”

Supplementary file 1_Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis... by Amany Behairy (22658510)

“…STL supplementation also restored hematological parameters altered by TDNPs exposure, including significant recovery of red blood cells, hemoglobin, packed cell volume, and white blood cells, thereby reversing macrocytic normochromic anemia and leukopenia. …”

Data Sheet 1_Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis niloticu... by Amany Behairy (22658510)

“…STL supplementation also restored hematological parameters altered by TDNPs exposure, including significant recovery of red blood cells, hemoglobin, packed cell volume, and white blood cells, thereby reversing macrocytic normochromic anemia and leukopenia. …”

Supplementary file 1_Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress.docx by Junhui Yu (8899847)

“…Fibrosis-related mRNA and pro-inflammatory mRNA expression were significantly decreased. Western blot results showed that UGP significantly inhibited the activation of p-ERK signaling. …”

Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... by Wenjing He (4278625)

“…Pro-inflammatory cytokines IL-6, IL-1β, and TNF-α levels were significantly suppressed (<i>p</i> < 0.001). Antioxidant enzyme activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) were restored, while lipid peroxidation (LPO) was reduced (<i>p</i> < 0.05). …”

Data_Sheet_1_Comparison of antimicrobial activities and resistance mechanisms of eravacycline and tigecycline against clinical Acinetobacter baumannii isolates in China.docx by Xiandi Chen (19729222)

“…Complementation of the wildtype adeN in TGC-resistant strains with the ISAba1 insertion in adeN restored TGC sensitivity and significantly downregulated adeIJK expression. …”

Table 1_Pig-L mediates virulence, biofilm formation, and oxidative stress tolerance in Clostridioides difficile.docx by Yumei Cheng (12111117)

“…</p>Results<p>Deletion of the pig-L gene resulted in a significant reduction in C. difficile virulence, decreased biofilm formation, and increased susceptibility to oxidative stress. …”

qorA associated data by fengning chen (20930834)

“…Transcriptomic and metabolic analyses indicated that the Δ<i>qorA</i> strain underwent a significant metabolic shift to cope with the redox imbalance. …”

Supplemental_Figure_of_Imeglimin_ameliorate_SA-AKI by Hiroyasu Goto (12227927)

“…The level of blood glucose decreased after E. coli challenge and was restored 48 h after E. coli challenge. …”

Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx by Jiali Liu (327739)

“…Pharmacodynamic evaluations, including pathological section analyses, demonstrated that KA effectively mitigated the fibrotic process and decreased collagen deposition. Further corroborated by ELISA experiments, kaempferol exhibited pronounced anti-fibrotic effects, inhibited inflammatory responses, restored liver function indices, and ameliorated the progression of liver fibrosis. …”

Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study by ShaSha Li (12163175)

“…</p> <p>The sKlotho level decreased significantly with kidney injury and represented severity. …”

NHR-49/80 mediated FEDUS via the peroxisomal activation. by Meiyu Ruan (19929335)

“…Lower population density significantly decreased palmitic acid-induced AWC maturation. …”

Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx by Demos Kynigopoulos (12420457)

“…</p>Results<p>Alirocumab significantly improved spatial working memory, restored hippocampal long-term potentiation, and normalized synaptophysin expression. …”

Table 1_Exogenous myo-inositol enhances drought tolerance in maize seedlings by antioxidant defense, and photosynthetic efficiency.docx by Yuqi Liu (501183)

“…</p>Results<p>The results demonstrate that MI significantly restored growth parameters under drought conditions, increasing shoot and root biomass by 40.74% and 28.30%, respectively, on Day 7. …”

Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc by Wenping Sun (1465360)

“…Lipidomic analysis revealed that Nar restored hepatic lipid homeostasis, significantly decreasing levels of TGs and diglycerides (DGs), with 20 differentially abundant lipid species identified as potential biomarkers. …”

Image 3_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”