CLIC1 accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells by inhibiting the Nrf2/HO-1 signalling pathway. حسب Jingtong Xiong (22272139)

"…(d) CCK-8 OD values were decreased after Nrf2/HO-1 inhibition, with lower values observed in the OGD/R+CLIC1 silencing+Nrf2/HO-1 inhibition group than the OGD/R+CLIC1 silencing group. …"

Table 3_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

"…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"

Table 1_High-concentrate diet supplemented with hydrolysable tannin improves the slaughter performance, intestinal antioxidant ability and barrier function of fattening lambs.docx حسب Jian Ma (170138)

"…Also, tannin supplementation significantly increased (p < 0.05) the level of jejunal and ileal total antioxidant capacity and reduced (p < 0.05) the jejunal malondialdehyde concentration in lambs. …"

Data Sheet 1_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.pdf حسب Meiling Liu (390553)

"…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …"

ROC curve. حسب Feng Zhang (6548)

"…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Supplementary file 1_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.d... حسب Yuezhou Huang (9998177)

"…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…"

DataSheet1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.PDF حسب Cong Zhang (582922)

"…Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …"

Protocol for our RNA-seq. حسب Sabih Rashid (5618807)

"…Top graphs depict genes increased in <i>daf-2; aak(0)</i> mutants compared to <i>daf-2</i> controls, while bottom graphs depict those genes that were decreased. Size of bubbles indicate number of genes in their respective categories that were enriched in the dataset. …"

Table4_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg حسب Yun Zhou (308977)

"…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …"

Supporting data for “<b>Human Lipocalin-2 Variants: Therapeutic Evaluations</b>” حسب Haoyun Li (9151469)

"…</p><p dir="ltr">Following a high-fat diet, our findings demonstrated that C87A levels were significantly elevated in cardiac and epididymal white adipose tissue (eWAT). …"

Table 1_Molecular, biofilm and motility characterization of Acinetobacter baumannii isolated from a neonatal intensive care unit at a children’s hospital in South China.xlsx حسب Zelin Yu (22500707)

"…Biofilm formation of ST1959 was significantly enhanced by gentamicin but inhibited by levofloxacin. …"

Image 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.tif حسب Haipeng Zhang (3413288)

"…NDEGs were significantly enriched in immune regulation and leukocyte apoptosis (GO) and NETs formation pathway (KEGG). …"

Table 2_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.doc حسب Feifei Yang (334047)

"…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …"

Image 4_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7... حسب Chunmei Ren (10921089)

"…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …"

Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf حسب Igor Larrañaga (5434382)

"…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …"

Table2_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.xlsx حسب Weina Xu (558990)

"…PTPRD-AS1 knockdown decreased the proliferation, cloning, and migration of CAOV3 cells.…"

Data Sheet 1_Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021... حسب Jiaxin Hao (18837682)

"…Background<p>Breast cancer is one of the most prevalent tumors worldwide, significantly compromising the survival and quality of life of patients. …"

Essential model parameters. حسب Chayanit Mahasing (19688403)

"…This study underscores the significance of the COVID-19 vaccine booster policy. …"

Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff حسب Priscila Silva (556743)

"…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"

Image 1_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"