Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…In addition, compound <b>E35</b> significantly inhibited colony formation and migration, as well as arrested the cell cycle at the S-phase. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…In addition, compound <b>E35</b> significantly inhibited colony formation and migration, as well as arrested the cell cycle at the S-phase. …”

Normal fetus at 32 weeks of gestation. by Inmaculada Villanueva-Baxarias (21454246)

Cox proportional hazard ratios. by Bryan S. Margulies (21492667)

“…Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. While many cytotoxic therapies increase p21 expression as a response to DNA damage, MBC-005 increased p21 expression independent cytotoxic DNA damage. …”

Bioluminescent Doubling Time. by Bryan S. Margulies (21492667)

“…Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. While many cytotoxic therapies increase p21 expression as a response to DNA damage, MBC-005 increased p21 expression independent cytotoxic DNA damage. …”

Study Design. by Bryan S. Margulies (21492667)

“…Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. While many cytotoxic therapies increase p21 expression as a response to DNA damage, MBC-005 increased p21 expression independent cytotoxic DNA damage. …”

Confirmed aortic coarctation case at 32 weeks of gestation. by Inmaculada Villanueva-Baxarias (21454246)

Predicting Dinitrogen Activation and Coupling with Carbon Dioxide and Other Small Molecules by Methyleneborane: A Combined DFT and Machine Learning Study by Feiying You (22119041)

“…The capture of carbon dioxide is extremely important due to the increasingly severe greenhouse effect, and the conversion of dinitrogen into high-value N–C compounds is of great significance. Here, we predict through density functional theory calculations that the coupling of dinitrogen with carbon dioxide by methyleneborane becomes favorable both thermodynamically and kinetically. …”

Apoptosis of MDA-MB-231 cells exposed to tick saliva. by Ana Carolina Prado Sousa (22265110)

Effect of tick saliva on HaCaT cells. by Ana Carolina Prado Sousa (22265110)

Effect of tick saliva on MDA-MB-231 cells. by Ana Carolina Prado Sousa (22265110)

Macroscopic morphology of 17-4PH-xTiC coatings. by Dian Yu Luo (22656111)

“…Compared to the commercial blade, the wear of the laser-cladded blade was decreased by 67%. This study successfully applied wear-resistant laser cladding coatings on the surface of harvester blades with small substrate thickness, significantly extending their service life.…”

SEM morphology of power: (a)17−4PH; (b)TiC. by Dian Yu Luo (22656111)

“…Compared to the commercial blade, the wear of the laser-cladded blade was decreased by 67%. This study successfully applied wear-resistant laser cladding coatings on the surface of harvester blades with small substrate thickness, significantly extending their service life.…”

SEM morphology of 17-4PH-xTiC coatings. by Dian Yu Luo (22656111)

“…Compared to the commercial blade, the wear of the laser-cladded blade was decreased by 67%. This study successfully applied wear-resistant laser cladding coatings on the surface of harvester blades with small substrate thickness, significantly extending their service life.…”

XRD patterns of 17-4PH-xTiC coatings. by Dian Yu Luo (22656111)

“…Compared to the commercial blade, the wear of the laser-cladded blade was decreased by 67%. This study successfully applied wear-resistant laser cladding coatings on the surface of harvester blades with small substrate thickness, significantly extending their service life.…”

Baseline characteristics of the study population. by Hanbin Wu (14016246)

“…</p><p>Conclusion</p><p>Preconception hypoglycemia was significantly associated with adverse pregnancy outcomes, and maternal preconception BMI could modify the association. …”

LA has minimal impact on HIV-1 virion integrity and surface levels of gp120 envelope protein. by Muriel Aldunate (22411177)

Virucidal activity of vaginal acids against HSV-2 and HPV-16. by Muriel Aldunate (22411177)

LA is a more potent inhibitor of HIV-1 virion-associated RT activity compared to acetic acid or low pH (HCl) alone. by Muriel Aldunate (22411177)

Virucidal activity of equimolar levels of the protonated form of vaginal LA, SCFAs, and succinic acid. by Muriel Aldunate (22411177)