Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf by Xue Bai (129175)

“…</p>Results<p>In HG/F-induced H9C2 cells, A-MG (1 and 3 μM) significantly increased cell viability (p < 0.01) and reduced LDH release (p < 0.05). …”

Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). by Hong Yan Huang (20135965)

“…P4HA3 and Ki-67 were decreased in the knockdown groups by siRNA compared to the NC group. …”

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

DataSheet1_Case report: Comprehensive clinical, pathological and genetic investigations to decipher the background of cyclic thrombocytopenia.pdf by Zsófia Flóra Nagy (19758660)

“…Whole exome sequencing revealed a heterozygous missense variant of uncertain significance in the SERPINC1 gene, which has been associated with hereditary antithrombin deficiency. …”

Key model formula. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Model framework. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Essential model parameters. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do... by Deliang Kong (382201)

“…</p>Conclusion<p>The study presents the true prevalence of PTB-DM comorbidity in the general population of Southwest China, revealing a significant upward trend in its prevalence and a higher risk of adverse outcomes among PTB-DM patients. …”

Data_Sheet_1_The functions and factors governing fungal communities and diversity in agricultural waters: insights into the ecosystem services aquatic mycobiota provide.pdf by Phillip Pham (407350)

“…</p>Discussion<p>Water physicochemical properties, including stream fungicide levels, explained a small proportion of the variation in mycobiota communities, underscoring the significance of unmeasured factors, alongside stochastic community assembly processes. …”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…To understand how reindeer grazing, coupled with changes in snow depth affects CO₂ exchange, we used recent snow treatments (ambient, reduced, and increased snow depth) combined with 25- and 55-year-old reindeer exclusions and the adjacent grazed areas in boreal and subarctic Scots pine forests that are main winter pastures for reindeer/caribou and cover a significant portion of boreal and subarctic landscapes. …”

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx by Mehri Hajiaghayi (19822665)

“…Nebivolol-treated β₂-knockout memory Th cells showed significant inhibition of β₂-AR-mediated signaling, evidenced by the absence of IL-17A suppression compared to controls. …”

<i>mig-21</i> sensitizes adult DTCs to polarizing signals. by Xin Li (51274)

“…However, migration cessation is not rescued; a significant increase in “overmigration” defects is observed between marked control (n=4/57) and <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=17/65), p < 0.05. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …”

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity by Mengyu Liu (2890397)

“…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …”

Table 1_Prevalence and prognostic value of sarcopenia in patients with bladder cancer undergoing radical cystectomy: a systematic review and meta-analysis.docx by Lei Zhang (38117)

“…</p>Objectives<p>This study was conducted to systematically evaluate the prognostic significance of sarcopenia in patients with bladder cancer undergoing RC.…”

Image 1_A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors.pdf by Huiyi Hu (11226995)

“…Moreover, survival analysis revealed the prognostic significance of this four-gene signature: high TOP2A with low ABLIM1, FHL5, and MAP3K8 expression correlated with decreased overall survival in ULMS, implicating their potential role as diagnostic and prognostic markers. …”

Motor imagery EEG microstates are influenced by alpha power by Xin Xiong (113595)

“…These findings suggest that alpha power influences microstate parameters differently depending on the brain, underscoring the significance of inter-band interactions in shaping microstate dynamics.…”