Flow cytometry gating strategy for MDSC. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 3. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 4. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

“…Amylomaltases (AMs) can modulate the biochemical properties of α-glucan through a distinctive cyclization feature to form α-1,4-glucoside-linked large-ring polysaccharides (cycloamyloses; CAs), endowing α-glucan with significant health benefits and medical value. While the industrial application of CAs continues to progress, the mechanistic intricacies of the cyclization processand its nuanced interplay with hydrolysisremain only partially understood. …”

Cataract induction does not affect hunting behaviour in optimal light conditions (left panels) but causes impairments in challenging light environments (right panels). by Amartya T. Mitra (14043115)

“…Similarly, under bright and UV light, we did not detect differences in hunting success (E,G; <i>n</i>_{<i>control</i>} = 12, <i>n</i>_{<i>lens3RNAi </i>}= 23, <i>p</i>_horizontal = 0.28, <i>p</i>_vertical = 0.23), but observed a weak (nonsignificant) decrease in the hunting success of treatment individuals under dim white light (F,H; <i>n</i>_{<i>control</i>} = 13, <i>n</i>_{<i>lens3RNAi </i>}= 22, <i>p</i>_horizontal = 0.22, <i>p</i>_vertical = 0.42).…”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope by Elena Kriukova (21524544)

“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”

Participant characteristics by village. by Tyler M. Barrett (20846174)

“…We hypothesized that farmers with greater market-based wealth and more farming experience would have higher odds of adaptation. …”

School learning model dispositions data. by David A. Katz (10056006)

“…P-values<0.050 were considered significant. From 2019 to 2021, reported persistent feelings of sadness/hopelessness (2019 = 36.3%, 2021 = 41.3%), seriously considering suicide (17.0-18.7%), making suicide plan(s) (14.2-16.9%), and experiencing sexual dating violence in past 12 months (6.7-7.8%) increased significantly, while alcohol use (22.5-17.1%), binge drinking (8.5-6.2%), and marijuana use (20.2-14.3%) in past 30 days, ever prescription opioid misuse (16.0-13.2%), and gun-carrying (5.5-4.5%), physical fighting (22.3-17.3%), and any sexual violence (11.3-10.4%) in past 12 months decreased significantly. …”

Description of the variables and data sources. by Borin Keo (20615176)

“…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …”

Descriptive statistics of the variables. by Borin Keo (20615176)

“…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …”

Eq 13. by Borin Keo (20615176)

“…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …”

Annual distribution of IG-ralated AE reports. by Shaozhi Liu (13720340)

“…In the overall population, the most significant signals included blood glucose abnormal (IC025 = 4.86), blood glucose fluctuation (IC025 = 4.69), blood glucose decreased (IC025 = 4.44), hypoglycaemic seizure (IC025 = 4.44) and hypoglycaemic unconsciousness (IC025 = 4.31). …”

Proportion of AEs by SOCs in pregnant women. by Shaozhi Liu (13720340)

“…In the overall population, the most significant signals included blood glucose abnormal (IC025 = 4.86), blood glucose fluctuation (IC025 = 4.69), blood glucose decreased (IC025 = 4.44), hypoglycaemic seizure (IC025 = 4.44) and hypoglycaemic unconsciousness (IC025 = 4.31). …”

Multiplex network of the VSTMBT and <i>nQ</i> example. by Avalon Campbell-Cousins (22110646)

Original data. by Kenji Sato (657309)

“…Additionally, a statistically significant improvement was observed in the Japanese Zarit Caregiver Burden Interview score at 6 months from baseline (p < 0.001).…”