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161
The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. We aim to review the available evidence on the metabolic effects of tirzepatide, focusing on weight loss and maintenance of lost weight, body composition alterations, appetite regulation, glycemic control, and lipid profile modulation. …”
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162
High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…<h3>Background </h3><p dir="ltr">In the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …”
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163
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
Published 2024“…<p dir="ltr">Schizophrenia presents significant diagnostic and treatment challenges, particularly in distinguishing between treatment-resistant (TRS) and non-treatment-resistant schizophrenia (NTRS). …”
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164
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”
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165
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…Upon rechallenge, in the animal group that had received WP1066 via o.g., the median survival was 18 days (95% CI: 17, NA), which was significantly different compared to naïve animals challenged at the same time that had a median survival of 11 days (95% CI; 10, NA) (p<0.001); however, there were only 10% long-term survivors suggesting that treatment alone did not generate significant long-term protective immunity. …”
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166
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
Published 2025“…Hemoglobin levels significantly increased from 6.4 to 11.1 g/dl (<i>p</i> < 0.001) after IV iron treatment, as did ferritin levels, while total iron-binding capacity decreased. …”
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167
Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden
Published 2002“…Cotrimoxazole resistance has also been increasing significantly in most hospitals, in spite of decreasing sales of cotrimoxazole and trimethoprim. …”
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168
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
Published 2023“…We hypothesized that these compounded challenges would have significant psychological implications on emerging adults, including university students, already vulnerable to life’s transitions involving self-discovery and independence. …”
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169
Improving the performance of a commercial absorption cooling system by using ejector: A theoretical study
Published 2023“…Finally, the absorber coil was found to have the most significance on the RACS performance in comparison with the rectifier coil and the refrigerant heat exchanger.…”
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170
Efficient multi-objective neural architecture search framework via policy gradient algorithm
Published 2024“…While the multi-objective NAS research addresses these challenges, the individual training required for each candidate architecture demands significant computational resources. …”
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171
Reduced graphene aerogels as energy efficient selective oil sorbents
Published 2022“…The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …”
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172
Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis
Published 2024“…In Lebanon, pharmacists face unique challenges stemming from an ongoing economic crisis, the COVID-19 pandemic, and a shifting healthcare landscape. …”
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173
Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
Published 2023“…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. Achieving resilience objectives in the built environment is challenging and requires the collaboration of all relevant sectors and professionals. …”
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174
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (p < 0.05). …”
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175
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
Published 2020“…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …”
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176
Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
Published 2022“…The concentration of malondialdehyde (MDA) and Cd accumulation (roots and shoots) increased significantly (P < 0.05) under the increasing levels of Cd in all genotypes of B. oleracea while antioxidant (enzymatic or non-enzymatic) capacity and nutritional status of the plants was decreased with varying levels of Cd in the sand. …”
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177
Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…Acute Myeloid Leukemia (AML) poses significant challenges due to its unfavorable prognosis and limited treatment options, particularly in elderly patients. …”
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178
Phosphate-solubilizing bacteria-mediated rock phosphate utilization with poultry manure enhances soil nutrient dynamics and maize growth in semi-arid soil
Published 2025“…The most pronounced improvements were in the treatment with 90-RP + 6-PM + PSB, which increased soil total N by 285%, available P by 79%, and available K by 51%. …”
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179
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”
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180
Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project
Published 2024“…Medical devices contribute to approximately 50% of these total HAPI. HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …”