Structural Alterations of the “Address” Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity by Hongguang Ma (5105198)

Subjects:

Starvation improves locomotory capacity and decreases the number of α-synuclein-YFP aggregates of transgenic <i>C. elegans</i> through LMP-1 dependent mechanism. by María Gallardo-Campos (22170919)

Evaluation of one-carbon cycle indicators between mouse groups (N=3 for each group). by Reyhane Aghajani (14237477)

Altered expression levels of mitochondrial complex proteins in prion infected mice. by Anne Ward (334296)

Alteration of total protein contents in cultured human skeletal muscle cells: Winter-hibernation period vs. summer-active period. by Mitsunori Miyazaki (197902)

Subjects:

Developmental delay of <i>rpS13/+</i> animals is not due to a decrease in ribosome numbers or reduced translation rates. by Lisa Patricia Deliu (13570709)

Phenotypic effects of SAUR63 variants with altered N-terminal sequences. by Punita Nagpal (185838)

<i>ogt-1; eel-1 +</i> Pan-neuronal OGT-1 have decreased sensitivity to electroshock and improved locomotion. by Nirthieca Suthakaran (11731101)

“…(A) Average time of recovery was significantly decreased in <i>ogt-1; eel-1</i> + Pan-neuronal OGT-1 worms, <i>Ogt-1(ok430) III; eel-1(bgg1) IV; bggSi2[Prab-3</i>::<i>ogt-1a] II</i> (n = 33), in comparison to <i>ogt-1;eel-1</i> double mutants (n = 30) but not significantly different from <i>eel-1</i> null mutants (n = 26). …”

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

HERVK HML-2 <i>env</i> knockdown decreases IFN-I expression and alters the secretory profile of THP1 monocytes and primary MDMs. by Natallia Mikhalkevich (10113822)

“…M-CSF-differentiated MDMs from n = 6 donors. * <i>p</i><0.05, ^NS non-significant, paired Wilcoxon test. …”

List of 1483 genes that were significantly (<i>P</i> < 0.1) increased or decreased in any galactose-treated sample. by Masaya Nagaya (13851123)

MAF1 protein expression is significantly decreased in luminal, HER2-positive, and TNBC breast cancer subtypes. by Stephanie Cabarcas-Petroski (9631636)

Subjects:

Blood concentration-time curve of n-butylphthalide in rats. by Xiangchen Li (512737)

Subjects:

A prepubertal CD decreases hepatic lipid accumulation in adulthood despite a chronic HFD in Sprague-Dawley male rats. by Ana Aguilar-Lozano (20614619)

Comparison of serum follicle-stimulating hormone (FSH) and Luteinizing hormone (LH) levels in mouse serum between groups (N=3 for each group). by Reyhane Aghajani (14237477)

Aβ and vGlut2 staining of 6-, 9-, and 12-month dLGN sections show significant plaque load and accelerated loss of retinal ganglion cell axon terminals in the 5xFAD mice. by Shaylah McCool (20818280)

SARS-CoV-2 decreases excitatory synapses, while influenza A does not induce cell death in BCO. by Pinar Mesci (14053895)

Alterations in CBC and blood chemistry parameters in VEEV-infected NHPs. by Henry Ma (6077057)

Table 1_A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity.xls by Wen Wang (6570)

“…</p>Conclusion<p>Our findings indicate that α-conotoxin [D1G, ΔQ14] LvIC significantly decreased locomotor activity in mice. Additionally, it altered gene expression primarily in areas related to neuronal development, synapse formation, and neuron activity, while also reducing synapse strength. …”

Table 2_A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity.xls by Wen Wang (6570)

“…</p>Conclusion<p>Our findings indicate that α-conotoxin [D1G, ΔQ14] LvIC significantly decreased locomotor activity in mice. Additionally, it altered gene expression primarily in areas related to neuronal development, synapse formation, and neuron activity, while also reducing synapse strength. …”