Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat حسب Hamdy, D. A.

"…With KTZ coadministered to hyperlipidemic rats, there were significant decreases in MDZ CL and VD. HL caused a decrease in unbound plasma fraction of oral KTZ but no significant difference in its pharmacokinetics. …"
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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…In addition, nicotine individually decreased expression levels of all examined protein targets, significantly for CYP1B1 (p < 0.001), CYP19A1 (p = 0.010), AhRR (p = 0.042), and ARNT (p < 0.001), compared to control. …"
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Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) حسب Saragusty, Joseph

"…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …"
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Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis حسب Jamialahamdi, Tannaz

"…Results: Meta-analysis of 11 clinical studies (n = 394 individuals) confirmed a significant reduction in SAA following bariatric surgery (SMD: − 0.971, 95% CI: − 2.721, 0.779, p < 0.001). …"
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Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings حسب Bello, Adewale Suraj

"…Heat stress (HS) is expected to become a significant abiotic stressor with the continued rise in global temperatures, severely limiting the development and production of bell pepper (Capsicum annuum L.), especially in arid and semiarid regions. …"
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The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells. حسب Attafi, Ibraheem M

"…Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. …"
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Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells حسب Alshwyeh, Hussah Abdullah

"…Furthermore, the extract exhibited higher toxicity towards NCI-H292 cells, followed by A549 and normal MRC-5 cells in decreasing order of potency. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort حسب Qafoud, Fatima

"…Classical regression and machine-learning models were used for risk score development. Results: Significant associations were observed with ECG traits. …"
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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

"…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …"
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Impact of magnetic dipole on a thermally stratified ferrofluid past a stretchable surface حسب Muhammad N.

"…This article focuses on the characteristics of a magnetic dipole in a viscous ferrofluid induced by linear stretched surface. …"
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Knowledge and Perception of and Attitude toward a Premarital Screening Program in Qatar: A Cross-Sectional Study حسب Al-Shafai, Mashael

"…Premarital screening (PMS) is a primary preventive measure to decrease the incidence of certain genetic disorders and sexually transmitted diseases. …"
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A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies حسب Mohamed Bakr, Hussain

"…Cadmium affects reproductive traits in Centropages ponticus, decreasing EPR and particularly HS. Furthermore, copper and chromium at high concentrations induce significant decreases in eggs per female in Notodiaptomus conifer. …"
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A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis حسب Tricarico, Paola Maura

"…Since several transcriptome studies have shown a significantly decreased expression of DCD in HS skin, we hypothesised that the identified frameshift insertion was a loss-of-function mutation that might be associated with HS susceptibility in this family. …"
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Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Reagu, Shuja Mohd

"…Results: 15.7% respondents report intent to not breastfeed. 21.4% respondents reported obsessive-compulsive symptoms. 77.3% respondents believed the biggest source of infection was from others while as only 12% of the respondents believed that the source of infection was through breastfeeding and 15.7% believed the vertical transmission as the main source of risk of transmission. Conclusions: The rates of Obsessive-compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. …"
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Changes in movement organization and control strategies when learning a biomechanically constrained gait pattern, racewalking: a PCA study حسب Majed, L.

"…With practice, the significant decrease in the variance accounted for by PC1 and in the correlations between many variables could indicate a destabilization of spontaneous tendencies to facilitate the adoption of more task-specific coordinative pattern. …"
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