Search alternatives:
significant degrees » significant decrease (Expand Search), significant degs (Expand Search), significant progress (Expand Search)
degrees decrease » degree increased (Expand Search)
side decrease » sizes decrease (Expand Search), fid decreased (Expand Search), we decrease (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
significant degrees » significant decrease (Expand Search), significant degs (Expand Search), significant progress (Expand Search)
degrees decrease » degree increased (Expand Search)
side decrease » sizes decrease (Expand Search), fid decreased (Expand Search), we decrease (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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Trypan blue dye exclusion assay for cell viability evaluation (% of control).
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Rate of apoptosis in MDA-MB-231 cells (ATO: 2.5 μM and GCB: 22.5 μM, 48 h, at 37°C).
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Rate of apoptosis in MCF-7 cells (ATO: 2.5 μM and GCB: 22.5 μM, 48 h, at 37°C).
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Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations
Published 2025“…Furthermore, we identify that postglycosylation noncovalent polysaccharide chain transfer emerges as the decisive factor in cyclization, particularly for AM–degree of polymerization (DP) greater than 30 substrate complexes, where this noncovalent step (≥13.6 kcal/mol) dictates the rate of CA production. 57 variants with enhanced activity (up to a 2.3-fold increase) were engineered in our biochemical experiments by strategically modulating the chain transfer step. …”