Image 3_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff by Priscila Silva (556743)

“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”

Descriptive Statistics. by Sayed Jubair Bin Hossain (22430672)

“…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…”

Data Sheet 1_Therapeutic potential of Glycyrrhiza polysaccharides in pseudorabies virus infection: immune modulation, antioxidant activity, and gut microbiota restoration.pdf by Chunlian Song (4635886)

“…</p>Results<p>GP administration significantly alleviated PRV-induced symptoms, reduced mortality and disease activity index, and improved food intake. …”

Table 1_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx by Shuman Li (652613)

“…NEAT1 knockdown inhibited cell migration, enhanced epithelial barrier integrity, and reversed EMT-associated cytoskeletal remodeling. E-cadherin levels increased, while N-cadherin and vimentin decreased. …”

Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx by Shuman Li (652613)

“…NEAT1 knockdown inhibited cell migration, enhanced epithelial barrier integrity, and reversed EMT-associated cytoskeletal remodeling. E-cadherin levels increased, while N-cadherin and vimentin decreased. …”

Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx by Chenyi Shao (6444911)

“…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …”

The result of the Negative Binomial Regression. by Sayed Jubair Bin Hossain (22430672)

“…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…”

Table 5_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…”

Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif by Meirong Feng (22089665)

“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”

Analysis of connexin 43 expression in mice inoculated intravenously with EVs (green) or ICs (blue). by Alberto Cornet-Gomez (10676133)

“…<p>Confocal microscopy revealed decreased connexin 43 synthesis in mice injected with EVs and ICs <b>(A)</b>. …”

A fast <i>in situ</i> hybridization chain reaction method in <i>Drosophila</i> embryos and ovaries by Kyohei Mikami (4237810)

“…Ethylene carbonate was added to the hybridization buffer to facilitate the hybridization reaction, and a modified short hairpin DNA was used in the amplification reaction; these modifications decreased the RNA staining time from 3 days to 1 day. …”

Structure of the OHC model. by Yihan Liao (13807348)

“…<p>In this study, we employed Depthwise Separable Convolution to significantly reduce the model's parameters, decreasing complexity, thus expediting training and reducing the risk of overfitting. …”

Image 1_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”

Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”

Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…</p>Results<p>E2-treated WT OVX immunized mice after intravaginal HSV-2 challenge showed significantly increased HSV-2-specific IgG2b and IgG2c antibodies in serum and vaginal secretions compared to placebo mice and enhanced B220-CD138+ IgG2c+ plasma cells within the nasal mucosa and vaginal tract 6-weeks after immunization. …”

Validation of an abortive response with elevated NF-κB activity distinct from full lytic reactivation. by Elliott D. SoRelle (6527681)

“…(D) Frequencies of <i>CD38</i>⁺ and <i>BCL2A1</i>⁺ cells presented in 3C by treatment condition at 24 h and 48 h. Asterisks denote significantly decreased frequencies of <i>CD38</i>⁺ cells and increased frequencies of <i>BCL2A1</i>⁺ cells upon 4HT and 4HT+PAA treatment versus respective control treatments (n = 3 per condition; two-tailed Welch’s t-test; **p<0.01). …”

Table_1_Major air pollution and climate policies in NYC and trends in NYC air quality 1998–2021.docx by Kathleen Lau (19855266)

“…In our CCCEH cohorts, between 1998 and 2016, the annual average PM_2.5 and NO₂ concentrations also decreased significantly by 51 and 48%, respectively. …”