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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Residential Demand Response Scheduling with Consideration of Consumer Preferences
Published 2016“…<p dir="ltr">This paper proposes a new demand response scheduling framework for an array of households, which are grouped into different categories based on socio-economic factors, such as the number of occupants, family decomposition and employment status. …”
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On-demand mobile sensing framework for traffic monitoring. (c2017)
Published 2017“…Unlike existing approaches that rely on opportunistic continuous sensing from all available cars, this ability to offer sensory data to consumers on demand can bring significant benefits to ITS and can constitute an efficient and flexible solution to the problem of real-time traffic/road data collection. …”
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An Infrastructure-Assisted Crowdsensing Approach for On-Demand Traffic Condition Estimation
Published 2019“…Our approach combines the strengths of mobile crowdsensing, with the support of the mobile infrastructure, a multi-criteria algorithm for the participants' selection, and a deductive rule-based model for traffic condition estimation. The proposed solution was validated through a combination of prototyping and simulated traffic traces, and the results show a significant reduction in terms of resources' consumption and network overhead, while reaching high accuracy for the traffic condition estimation.…”
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A novel on-demand vehicular sensing framework for traffic condition monitoring
Published 2018“…When compared to the traditional continuous sensing, our proposed on-demand sensing approach provides comparable high traffic estimation accuracy while significantly reducing the resource consumption. …”
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Analysis and Quantification of Demand Flexibility for Resilient Distribution Networks: A Systematic Review
Published 2025“…<p dir="ltr">Modern power systems face increasing operational challenges due to the integration of renewable energy sources (RESs) and evolving demand patterns. Demand flexibility (DF) has emerged as a transformative solution by dynamically adjusting electricity consumption to align with grid conditions. …”
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Data-Driven Electricity Demand Modeling for Electric Vehicles Using Machine Learning
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A Stackelberg Game Inspired Model of Real-Time Economic Dispatch with Demand Response
Published 2021“…Traditional electric power systems have several challenges in maintaining their reliability and being able to meet the demand of the consumers at peak hours. Additionally, environmental concerns may arise from several physical limitations in the network that would increase gas emission besides adding extra generation costs. …”
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A Literature Review on System Dynamics Modeling for Sustainable Management of Water Supply and Demand
Published 2023“…<p dir="ltr">Water supply and demand management (WSDM) is essential for developing sustainable cities and societies. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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