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significant effect » significant impact (Expand Search)
effect decrease » effects decreased (Expand Search)
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13261
DataSheet1_Targeting AXL cellular networks in kidney fibrosis.docx
Published 2024“…</p>Results<p>Preventive treatment with bemcentinib significantly attenuated fibrosis in the UUO model. The anti-fibrotic effect correlated with a decrease in mesangial cells and inhibition of innate immune cell infiltration, while the proportion of epithelial cells increased. …”
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13262
Data Sheet 1_Antibiotic subclasses differentially perturb the gut microbiota in kidney transplant recipients.pdf
Published 2024“…</p>Results<p>Antibiotic administration was associated with a significant decrease in the Shannon alpha diversity index, a decreased abundance of 11 taxa including Eubacterium and Ruminococcus, and an increased abundance of 16 taxa including Enterococcus and Staphylococcus. …”
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13263
Image1_Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury.tif
Published 2024“…Hemopexin (Hx) is the major serum scavenger protein for heme, which is a prooxidant and pro-inflammatory compound. In the current study, we hypothesized that Hx could confer beneficial effects in sterile inflammation induced by IR-mediated lung injury.…”
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13264
Image2_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.tif
Published 2024“…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …”
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13265
Table1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.pdf
Published 2024“…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …”
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13266
Image1_DDIT4/mTOR signaling pathway mediates cantharidin-induced hepatotoxicity and cellular damage.png
Published 2024“…CTD led to a significant increase in the mRNA and protein levels of DDIT4 in both liver tissue and L-O2 cells, as well as a significant increase in LC3-II, Beclin1, and Bax, whereas p-mTOR and Bcl-2 were significantly decreased. …”
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13267
Table 1_Evaluation of clopidogrel responsiveness using the Platelet Function Analyzer-200 (PFA-200) in dogs.docx
Published 2025“…Among the assessed parameters, only D-dimer levels showed a significant decrease in the clopidogrel-responder group (p < 0.05), suggesting its potential utility in evaluating responsiveness. …”
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13268
Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx
Published 2025“…Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”
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13269
Data Sheet 1_The facultative intracellular symbiont Lariskella is neutral for lifetime fitness and spreads through cytoplasmic incompatibility in the leaffooted bug, Leptoglossus z...
Published 2025“…Lifetime survival analysis (~120 days) showed significant developmental delays and decrease in survival for bugs that lacked Caballeronia, and Caballeronia-free bugs did not reproduce. …”
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13270
Supplementary file 1_The facultative intracellular symbiont Lariskella is neutral for lifetime fitness and spreads through cytoplasmic incompatibility in the leaffooted bug, Leptog...
Published 2025“…Lifetime survival analysis (~120 days) showed significant developmental delays and decrease in survival for bugs that lacked Caballeronia, and Caballeronia-free bugs did not reproduce. …”
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13271
Image 1_Evaluation of clopidogrel impact on canine platelet function using flow cytometry and thromboelastography platelet mapping.tif
Published 2025“…</p>Results<p>TEG analysis demonstrated a significant reduction in ADP-induced clot strength following clopidogrel administration (p < 0.05), indicating effective platelet inhibition. …”
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13272
DataSheet1_Unveiling the proteome of the fasting heart: Insights into HIF-1 pathway regulation.PDF
Published 2024“…<p>Fasting is a common dietary intervention known for its protective effects against metabolic and cardiovascular diseases. …”
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13273
Data Sheet 1_CMOS-fabricated dielectrophoretic chip with embedded 3D TiN nano-electrode arrays for sperm capture and sperm damage reduction.docx
Published 2025“…</p>Results and discussion<p>The results showed that square waves improved capture efficiency by approximately10% and confirmed that the capture space must exceed half the sperm length to enhance efficiency. When operated under a 20 Vpp square wave, the chip only generated a temperature rise of 1.7°C, causing no significant damage to the sperms and no notable decrease in viability. …”
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13274
Video 2_CMOS-fabricated dielectrophoretic chip with embedded 3D TiN nano-electrode arrays for sperm capture and sperm damage reduction.mp4
Published 2025“…</p>Results and discussion<p>The results showed that square waves improved capture efficiency by approximately10% and confirmed that the capture space must exceed half the sperm length to enhance efficiency. When operated under a 20 Vpp square wave, the chip only generated a temperature rise of 1.7°C, causing no significant damage to the sperms and no notable decrease in viability. …”
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13275
Video 1_CMOS-fabricated dielectrophoretic chip with embedded 3D TiN nano-electrode arrays for sperm capture and sperm damage reduction.mp4
Published 2025“…</p>Results and discussion<p>The results showed that square waves improved capture efficiency by approximately10% and confirmed that the capture space must exceed half the sperm length to enhance efficiency. When operated under a 20 Vpp square wave, the chip only generated a temperature rise of 1.7°C, causing no significant damage to the sperms and no notable decrease in viability. …”
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13276
ALKBH5 induces macrophage activation to promote renal fibrosis via Retnla
Published 2025“…RNA sequencing indicated that Resistin-like alpha (Retnla) was the downstream target of ALKBH5, and treatment with recombinant Retnla abrogated the effect of ALKBH5 deficiency on renal fibrosis. We conclude that ALKBH5-dependent regulation of macrophage and kidney fibrosis progression through Retnla represents a novel strategy for patients with chronic kidney disease.…”
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13277
Data from: Does green stem photosynthesis affect plant drought tolerance and recovery in avocado?
Published 2025“…However, we observed an increase in hydraulic conductivity during the drought period with an increase in the concentration of sugars in the sapwood and a decrease in the concentration of starch, suggesting osmotic adjustment. nulltheless, the contribution of carbon gain through stem photosynthesis may not play a significant role in hydraulic functioning of avocado under these conditions.…”
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13278
Table 1_Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial.pdf
Published 2025“…MB was associated with a significant decrease in cytophilic subclasses IgG1 and IgG3 to S and S2, and IgA to RBD, S and S2 in CCP units IgA to RBD, S and S2 in CCP units, without a reduction in neutralization titer and with a modest increase in IgG2 to RBD and S.…”
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13279
Image 4_Pediatric kidney transplant recipients are at an increased risk for dysbiosis.jpeg
Published 2025“…Conversely, there was a decrease in bacterial genera belonging to the phylum Firmicutes. …”
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13280
Image 1_Pediatric kidney transplant recipients are at an increased risk for dysbiosis.jpeg
Published 2025“…Conversely, there was a decrease in bacterial genera belonging to the phylum Firmicutes. …”