Search alternatives:
significant effect » significant impact (Expand Search)
largest decrease » marked decrease (Expand Search)
effect decrease » effects decreased (Expand Search)
larger decrease » marked decrease (Expand Search)
significant effect » significant impact (Expand Search)
largest decrease » marked decrease (Expand Search)
effect decrease » effects decreased (Expand Search)
larger decrease » marked decrease (Expand Search)
-
7861
Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx
Published 2025“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”
-
7862
Image 5_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
-
7863
Image 8_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg
Published 2025“…</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. Western blot analysis demonstrated that SMCl effectively suppressed hepatocellular carcinoma proliferation by markedly inhibiting the RAS/RAF/MEK/ERK signaling pathway, with this inhibitory effect exhibiting both time- and concentration-dependent characteristics. …”
-
7864
Table 1_Differences in the dynamic balance function of healthy elementary school students and university students observed with and without the use of a sensor-integrated gamificat...
Published 2025“…</p>Results<p>During the Y-Balance test, all items exhibited no significant interaction effects; however, several outcome measures exhibited main effects. …”
-
7865
Supplementary Material for: Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis
Published 2025“…In vitro, NETosis enhanced tumor necrosis factor-α (TNF-α) release from mesangial cells, an effect that was mitigated by GSK484. RNA-seq analysis of kidneys from GSK484-treated IgAN mice also revealed significant alterations in the PPAR signaling pathway. …”
-
7866
Table 2_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.docx
Published 2025“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”
-
7867
Table 3_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.docx
Published 2025“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”
-
7868
Data Sheet 1_DYRK1A roles in human neural progenitors.docx
Published 2025“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …”
-
7869
Table 4_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.docx
Published 2025“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”
-
7870
Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf
Published 2025“…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). In PASMCs stimulated with PDGF-BB, a similar trend of increased p-PKC, p-IRS-1(Ser318), and p-ERK levels was observed, along with a decrease in IRS-1 expression. …”
-
7871
Table 1_Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat.docx
Published 2025“…In contrast, DLAN male offspring exhibited a significant decrease in social play behavior compared to LD animals, which was associated with higher numbers of microglia in the NAc that had more ramified morphology. …”
-
7872
Image 1_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.jpeg
Published 2025“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”
-
7873
Table 1_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.docx
Published 2025“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”
-
7874
Image 2_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.jpeg
Published 2025“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”
-
7875
Presentation 1_Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study.pdf
Published 2025“…Additionally, the intervention augmented by digital health components likely exerted some protective effects against the impact of COVID-19 containment strategies. …”
-
7876
The rental distance in battery swap scenario.
Published 2024“…The model is evaluated using a baseline scenario for Shanghai, exploring the effects of vehicle range, charging capabilities, and power supply strategies on the uptake of shared autonomous electric vehicles. …”
-
7877
Five main steps of MATSim.
Published 2024“…The model is evaluated using a baseline scenario for Shanghai, exploring the effects of vehicle range, charging capabilities, and power supply strategies on the uptake of shared autonomous electric vehicles. …”
-
7878
Data Sheet 1_Efficacy and safety of topical minocycline preparations for papulopustular rosacea: a systematic review and meta-analysis.pdf
Published 2025“…Topical minocycline allow the delivery of high concentrations of the medication to the skin while decreasing systemic exposure thereby evading side effects (Jones et al., 2021, Webster et al., 2020). …”
-
7879
EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1
Published 2025“…</p> <p>We found a significant effect on genes that play roles in inflammation and detoxification processes in the body. …”
-
7880
Supplementary Material for: Impact of Ketogenic Diet on Weight, Metabolic, and Endocrine Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Published 2025“…Moreover, LH concentrations were significantly reduced (SMD 1.12 ng/dL [0.39, 1.84] p=0.003), FSH levels raised (SMD -0.76 ng/dL [-1.25, -0.28], p=0.002), the LH/FSH ratio decreased (SMD 2.04 (95% CI 1.04-3.03, p<0.001); testosterone decreased (free-T SMD 0.57 ng/dL [95% CI 0.28, 0.86], p<0.001; total-T SMD 0.54 ng/dL, 95% CI 0.28, 0.80, p<0.001), and SHBG levels were significantly increased (SMD 0.79, 95% CI [1.24-0.34],p<0.001). …”