Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis by Abouzid, Afaf

“…Notably, %TNF-α dramatically decreased to 57 ± 4.05% of control, for cells treated with drug-free liposomes (500 μg/mL total lipid) indicating the anti-inflammatory activity of SPC lipid component per se, which led to synergistic effect as evident from the augmentation of AMX anti-inflammatory activity in D-L1 formulation. …”
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High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury by Stanley, Ibeh

“…Also, cell proliferation post-TBI was repressed by HFD, which was accompanied by an increased lesion volume. SignificanceOur research indicated that chronic HFD feeding can worsen functional outcomes, predispose to neurodegeneration, and decrease brain recovery post-TBI. …”
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Platelet Concentrate Treatments for Temporomandibular Disorders: A Systematic Review and Meta-analysis by Al-Hamed F.S.

“…The meta-analysis revealed that PCs decreased pain visual analogue scale (VAS) scores compared to HA by an average of ?…”
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…Additionally, the mean power spectral density of the EMG signal decreased notably post-training. ConclusionThis study presents a structured approach for hypospadias training and highlights the effectiveness of wearable sensor technology for objective skill assessment. …”
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The Impact of COVID-19 on Physical (In)Activity Behavior in 10 Arab Countries by Al Sabbah, Haleama

“…Physical activity levels decreased significantly during the lockdown. Participants' country of origin, gender, and education were associated with physical activity before and during the lockdown (p < 0.050). …”
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Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats by Kiss, K.

“…The positive control BNP significantly decreased infarct size in studies 1–3 by approximately 35%. …”
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Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes by Younes, Noura B.

“…Results: DHA-treated hypoxic cells showed significantly decreased basal free fatty acid release, lactate production, and enhanced glucose consumption. …”
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Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress by Hammad, Ayat Samir

“…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. Pre-treatment of cells with piperine and its cyclohexylamino analog decreased the tunicamycin-induced upregulation of GRP78 and CHOP. …”
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Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros by Mesmar, J.

“…Pretreatment with N-acetylcysteine, an ROS scavenger, attenuated the anti-proliferative effect of ZNE. In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …”
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters by Awad A.M.

“…The drill pipe rotation has the dominant effect on the performance of cuttings transportation, with the effect are more pronounced for highly deviated and horizontal wells. …”
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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Santosh K., Yadav

“…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …”
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Rare case of norethisterone-induced hepatitis: A case report. by Arafa, Eiman A

“…Upon discontinuation of norethisterone, liver transaminases decreased to normal level within two weeks. Knowledge of rare adverse effects of drugs such as norethisterone is necessary for rapid identification and management, especially in patients with risk factors such as non-alcoholic liver disease and obesity.…”
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Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Yadav, Santosh K.

“…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …”
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Improving mechanical, thermal and damping properties of niti (Nitinol) reinforced aluminum nanocomposites by Matli, Penchal R.

“…Compared to the unreinforced aluminum, hardness, ultimate compression/tensile strength and yield strength increased by 105%, 46%, 45%, and 41% while elongation and coefficient of thermal expansion (CTE) decreased by 49% and 22%, respectively. The fabricated Al-1.5 NiTi nanocomposite exhibited significantly higher damping capacity (3.23 × 10−4) and elastic modulus (78.48 ± 0.008 GPa) when compared to pure Al.…”
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The maxima in northerly wind speeds and wave heights over the Arabian Sea, the Arabian/Persian Gulf and the Red Sea derived from 40 years of ERA5 data by Aboobacker, V.M.

“…The northern Arabian Sea including the Sea of Oman exhibits significant decreasing trend in northerly maximum wind speed (− 1.4 cm/s/year) and Hs (− 0.67 cm/year), while the Gulf and the Red Sea exhibit sectorial contrasting trend, indicating the dominance of localized effects in modifying the regional climate. …”
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Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties by Mesmar, Joelle

“…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. Additionally, only higher concentrations of OSEE were able to attenuate inhibition of proliferation induced by the ROS scavenger N-acetyl cysteine (NAC), indicating that the anti-proliferative effects of OSEE could be ROS-dependent. …”
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Impact of moisture contents on the performance of organic bi-layer ITO/OD thermo-electric cells by Ahmad, Zubair

“…The experimental results clearly show that with the increase of temperature Seebeck coefficient increases, whereas with increasing moisture contents the Seebeck coefficient of the ITO/OD thermo-electric cell significantly decreases. Our results point out the need for well-controlled environmental conditions, predominantly moisture level, in order to appraise the thermo-electric performance of organic semiconductor materials. 2016, Springer Science+Business Media New York.…”
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A vector quantization based k-NN approach for large-scale image classification by Ozan, Ezgi Can

“…However, with the growth of the size of image datasets and the number of dimensions of image descriptors, popularity of k-NNs has decreased due to their significant storage requirements and computational costs. …”
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INVESTIGATING THE MOLECULAR MECHANISMS UNDERLYING THE ANTI-CANCER ACTIVITIES OF DIOSMETIN IN COLORECTAL CANCER CELLS: AN IN VITRO STUDY by AHMED, SABAH NISAR

“…The results revealed that Diosmetin exerts significant cytotoxic effects on HCT116 cells as indicated by decreased cell viability and proliferation, increased DNA damage, loss of mitochondrial membrane potential (MMP), cell cycle arrest, and induction of apoptosis. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S., El-Shoukrofy

“…Notable COX-2 inhibitory activities (IC50 = 0.065–0.24 μM) were observed relative to celecoxib (IC50 = 0.049 μM). The two most effective 15-LOX inhibitors, 2a and 2b, exhibited 69 % and 57 % of quercetin's action, respectively. …”
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