Image_1_Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone.jpeg by Dandan Luo (1415938)

“…However, the mechanisms underlying the Leydig cell aging and the effects of obesity on Leydig cell aging remain unclear.…”

Table_1_Investigation Into the Relationship Between Sperm Cysteine-Rich Secretory Protein 2 (CRISP2) and Sperm Fertilizing Ability and Fertility of Boars.docx by Fenglei Gao (1869325)

“…The cleavage rate was significantly decreased by adding the anti-CRISP2 antibody to the IVF medium, which indicates CRISP2 plays a critical role in fertilization. …”

Table_2_Course of psychotic experiences and disorders among apprentice traditional health practitioners in rural South Africa: 3-year follow-up study.docx by Martine C. E. van der Zeijst (13879148)

“…</p>Results<p>At 3-year follow-up, psychotic experiences were associated with significantly less distress and there was a reduction in frequency of psychotic symptoms compared to baseline. …”

Image10_17β-Estradiol Treatment Improves Acetylcholine-Induced Relaxation of Mesenteric Arteries in Ovariectomized UC Davis Type 2 Diabetes Mellitus Rats in Prediabetic State.JPEG by Md Rahatullah Razan (12889721)

“…Overall, our data suggest that 1) the impairment of ACh responses in PD OVX rats may, in part, result from the elevated contractile responses to PE, loss of contribution of endothelium-dependent hyperpolarization (EDH) to vasorelaxation, and a decreased sensitivity of MA to nitric oxide (NO), and 2) the basis for the protective effects of E₂ may be partly attributed to the elevation of the NO contribution to vasorelaxation and its interaction with MA as well as potential improvement of insulin signaling. …”

Table_1_MASP-1 Increases Endothelial Permeability.docx by Márta L. Debreczeni (6661583)

“…Furthermore, in a whole-transcriptome microarray analysis MASP-1 significantly changed the expression of 25 permeability-related genes in HUVECs—for example it up-regulated bradykinin B2 receptor expression. …”

Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif by Jing Wang (6206297)

“…Furthermore, univariate and multivariate Cox analysis were used to assess the prognostic effects of ARPs. The investigation of immune cell infiltration and possible functional enrichment followed. …”

Table_1_Foliar application of salicylic acid inhibits the cadmium uptake and accumulation in lettuce (Lactuca sativa L.).xlsx by Wen Tang (165254)

“…</p>Methods<p>This study evaluated the effects of different concentrations of SA (0, 25, 100, 200, and 500 mg/L) on the growth and cadmium (Cd) content of lettuce (Lactuca sativa L.) under Cd stress. …”

Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx by Rong Su (2210740)

“…</p>Discussion<p>Our study reveals that the RMRM risk model could effectively predict the prognosis of HCC, and SPP1⁺ macrophages regulated by miR-4739-RNA methylation promote the proliferation and migration of HCC cells. …”

Image 3_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... by Shao-jun Xu (11633956)

“…The dynamic mortality risk rate revealed a double peak in the high-risk patients (12 and 48 months) and a single peak in the low–risk patients (24 months) and middle-risk patients (12 months), which gradually decreased over time.</p>Conclusion<p>The SNS staging based on IPI and clinicopathological features can thus be applied to effectively evaluate the OS and DFS of ESCC patients after MIE. …”

Data_Sheet_1_Impact of Non-cardiac Comorbidities on Long-Term Clinical Outcomes and Health Status After Acute Heart Failure in China.docx by Xiqian Huo (463197)

“…The findings highlight the need to address the management of comorbidities effectively in standardized HF care.</p>…”

Table_1_Obese Individuals With and Without Phlegm-Dampness Constitution Show Different Gut Microbial Composition Associated With Risk of Metabolic Disorders.xlsx by Juho Shin (12708395)

“…At the genus level, Faecalibacterium, producing short-chain fatty acid, achieving anti-inflammatory effects and strengthening intestinal barrier functions, was depleted in the PDC group, instead, Prevotella was enriched. …”

Data_Sheet_1_Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells.pdf by Cheng-Lu Hsieh (5591168)

“…In contrast to GAS, supplementation with exogenous nicotinamide did not effectively inhibit the growth of MRSA or S. Typhimurium in endothelial cells. …”

datasheet1_Suppression of Esophageal Cancer Stem-like Cells by SNX-2112 Is Enhanced by STAT3 Silencing.zip by Dan-dan Xu (3766957)

“…Flow cytometry analysis revealed that the combination of SNX-2112 and shSTAT3 significantly induced apoptosis and cell cycle arrest at G2/M phase in ECSLCs. …”

Image_1_Temporal–spatial variability of grazing behaviors of yaks and the drivers of their intake on the eastern Qinghai-Tibetan Plateau.pdf by Xiaoqian Yang (797525)

“…</p>Results<p>We showed that grazing behaviors of yaks differed significantly within hours, among hours of each day and among days as well as across different observation sites. …”

Image1_Efficacy and Safety of a Polysaccharide-Based Natural Substance Complex in the Treatment of Obesity and Other Metabolic Syndrome Components: A Systematic Review.TIF by Giuseppina Guarino (6795282)

“…</p><p>Conclusion: Policaptil Gel Retard^® is an effective and safe non-pharmacological approach to improve the treatment of MetS-associated cardiovascular risk factors in children, adolescents, and adults.…”

Image_3_Reversal of Endothelial Extracellular Vesicle-Induced Smooth Muscle Phenotype Transition by Hypercholesterolemia Stimulation: Role of NLRP3 Inflammasome Activation.tiff by Xinxu Yuan (7446968)

“…Using a Western diet (WD)-induced hypercholesterolemia mouse model, we found that endothelial-specific AC gene knockout mice (Asah1^fl/fl/EC^Cre) exhibited augmented WD-induced EV secretion with IL-1β and more significantly decreased the interaction of MVBs with lysosomes in the carotid arterial wall compared to their wild-type littermates (WT/WT). …”

Image_1_Inhibition of CAL27 Oral Squamous Carcinoma Cell by Targeting Hedgehog Pathway With Vismodegib or Itraconazole.tif by Raíza Dias Freitas (9621278)

“…Vismodegib and itraconazole significantly reduced CAL27 cell viability after 48 h of treatment. …”

Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif by Rong Su (2210740)

“…</p>Discussion<p>Our study reveals that the RMRM risk model could effectively predict the prognosis of HCC, and SPP1⁺ macrophages regulated by miR-4739-RNA methylation promote the proliferation and migration of HCC cells. …”

Image8_17β-Estradiol Treatment Improves Acetylcholine-Induced Relaxation of Mesenteric Arteries in Ovariectomized UC Davis Type 2 Diabetes Mellitus Rats in Prediabetic State.JPEG by Md Rahatullah Razan (12889721)

“…Overall, our data suggest that 1) the impairment of ACh responses in PD OVX rats may, in part, result from the elevated contractile responses to PE, loss of contribution of endothelium-dependent hyperpolarization (EDH) to vasorelaxation, and a decreased sensitivity of MA to nitric oxide (NO), and 2) the basis for the protective effects of E₂ may be partly attributed to the elevation of the NO contribution to vasorelaxation and its interaction with MA as well as potential improvement of insulin signaling. …”

Table 1_NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patie... by Xiaohui Zhang (81778)

“…NLR, PLR and SII provided us a quick, simple and cost-effective supervision way in monitoring and managing LN patients.…”