Showing 55,721 - 55,740 results of 55,881 for search '(( significant effect decrease ) OR ( significant ((step decrease) OR (linear decrease)) ))', query time: 1.13s Refine Results
  1. 55721

    Image 6_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…Background<p>Previous research has confirmed that integrating PD-1/PD-L1 inhibitors with chemotherapy (PC) represents a more effective strategy for treating advanced non-small-cell lung cancer (NSCLC). …”
  2. 55722

    Image_1_Disrupted metabolic signatures in amniotic fluid associated with increased risk of intestinal inflammation in cesarean section offspring.tif by Yongjie Liu (3166032)

    Published 2023
    “…Herein, we investigated the impact of CS delivery on colonic inflammation and mechanisms underlying these effects in offspring.</p>Methods<p>CS mice model and dextran sulfate sodium (DSS)-induced colitis model were constructed and used to analyze the impact of CS on the development of colitis. …”
  3. 55723

    image_5.pdf by Catalina Burbano (4900783)

    Published 2018
    “…The proportion and number of non-classical monocytes were significantly decreased in patients with SLE compared with HCs and in patients with aSLE compared with patients with the inactive disease. …”
  4. 55724

    Table 7_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx by Fan Lin (625737)

    Published 2025
    “…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.…”
  5. 55725

    Image_2_Consumer Attitude Toward the Environmental Sustainability of Grain-Free Pet Foods.PDF by Danielle M. P. Conway (5781986)

    Published 2018
    “…When participants already feeding a GFD were isolated, they demonstrated a higher likelihood to feed a GFD both before and after reading the pamphlet than the remaining population; however, the likelihood decreased from 8.4 ± 2.7 to 7.8 ± 2.7. The informational brochure was effective; participants were less likely to feed a GFD after reading the brochure. …”
  6. 55726

    Image 3_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... by Yun Xu (139234)

    Published 2025
    “…Background<p>Previous research has confirmed that integrating PD-1/PD-L1 inhibitors with chemotherapy (PC) represents a more effective strategy for treating advanced non-small-cell lung cancer (NSCLC). …”
  7. 55727

    Table_1_The local skin cellular immune response determines the clinical outcome of sarcoptic mange in Iberian ibex (Capra pyrenaica).pdf by Marta Valldeperes (10336170)

    Published 2023
    “…</p>Results<p>An inflammatory infiltrate that decreased significantly from 26 to 103 dpi was observed in all the infested ibexes. …”
  8. 55728

    Image_1_Mice Heterozygous for the Sodium Channel Scn8a (Nav1.6) Have Reduced Inflammatory Responses During EAE and Following LPS Challenge.tif by Barakat Alrashdi (7863197)

    Published 2021
    “…In the optic nerve, myeloid cell infiltration and the effects of EAE on the axonal ultrastructure were also significantly reduced in Scn8a<sup>dmu/+</sup> mice. …”
  9. 55729

    Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... by Mingzheng Duan (11630632)

    Published 2024
    “…These findings not only deepen our understanding of the continuous cropping issues but also pave the way for developing effective strategies to overcome them.</p>…”
  10. 55730

    image_3.pdf by Catalina Burbano (4900783)

    Published 2018
    “…The proportion and number of non-classical monocytes were significantly decreased in patients with SLE compared with HCs and in patients with aSLE compared with patients with the inactive disease. …”
  11. 55731

    Image_3_Limbic oxytocin receptor expression alters molecular signaling and social avoidance behavior in female prairie voles (Microtus ochrogaster).TIF by Lina K. Nerio-Morales (19142107)

    Published 2024
    “…Oxytocin receptors activate the mitogen-activated protein kinase (MAPK) pathway, which has been previously associated with the anxiolytic effects of oxytocin. Here, we assessed the functional significance of OXTR in stress-induced social avoidance and the response of the MAPK signaling pathway in the nucleus accumbens (NAc), anterior cingulate cortex (ACC), and basolateral amygdala (BLA) of female prairie voles.…”
  12. 55732

    Enhanced viability and function of mesenchymal stromal cell spheroids is mediated <i>via</i> autophagy induction by Shobha Regmi (3134358)

    Published 2021
    “…Recently, three dimensional (3D)-cultured MSCs (MSC<sub>3D</sub>) were shown to have higher cell survival and enhanced anti-inflammatory effects, although the underlying mechanisms have not yet been elucidated. …”
  13. 55733

    Enhanced drug resistance suppression by serum-stable micelles from multi-arm amphiphilic block copolymers and tocopheryl polyethylene glycol 1000 succinate by Lei He (143930)

    Published 2024
    “…Additionally, 4A-PEG<sub>47</sub>-b-PCL<sub>21</sub>/TPGS micelles effectively suppressed drug-resistant MCF-7/ADR cells.…”
  14. 55734

    Data_Sheet_1_Anaerobic Conversion of Saline Phenol-Containing Wastewater Under Thermophilic Conditions in a Membrane Bioreactor.docx by Julian D. Muñoz Sierra (9443015)

    Published 2020
    “…However, under such harsh conditions, effective biomass immobilization is difficult, limiting the use of the commonly applied sludge bed reactors. …”
  15. 55735

    Supplementation strategies affect the feed intake and performance of grazing replacement heifers by Wagner S. Machado (7387994)

    Published 2019
    “…Heifers fed ENE had decreased CP digestibility compared to PRO and CON heifers. …”
  16. 55736

    Table_1_Arterial oxygenation and acid–base status before and during oxygen supplementation in captive European bison (Bison bonasus) immobilized with etorphine-acepromazine-xylazin... by Nino Gardoni (16316643)

    Published 2023
    “…We evaluated the efficiency and physiological effects of an etorphine-acepromazine-xylazine combination with supplemental oxygen in 39 captive European bison. …”
  17. 55737

    Image_1_Lipidomics profiles of human spermatozoa: insights into capacitation and acrosome reaction using UPLC-MS-based approach.pdf by Xiaohong Cheng (275970)

    Published 2023
    “…The maintenance of lipid homeostasis, essential for cell health, significantly influences the survival, maturation, and functionality of sperm during fertilization. …”
  18. 55738

    DataSheet_1_A Novel Tree Shrew Model of Chronic Experimental Autoimmune Uveitis and Its Disruptive Application.pdf by Kaijiao Hu (8978402)

    Published 2022
    “…RGS4 inhibition and dihydroartemisinin could significantly alleviate the retinal pathological injuries of IRBP<sub>1197-1211</sub>-induced EAU by decreasing the expression of CD4 T-cells.…”
  19. 55739

    DataSheet_1_IL-10 Deficiency Accelerates Type 1 Diabetes Development via Modulation of Innate and Adaptive Immune Cells and Gut Microbiota in BDC2.5 NOD Mice.docx by Juan Huang (41654)

    Published 2021
    “…Moreover, in vivo studies demonstrated that the depletion of endogenous gut microbiota by antibiotic treatment decreased the proportion of neutrophils. Although Il-10 deficiency in BDC2.5<sup>+</sup> NOD mice had no obvious effects on the proportion and function of Treg cells, it affected the immune response and activation of CD4<sup>+</sup> T cells. …”
  20. 55740

    DataSheet_1_Innate Immune Responses to Chimpanzee Adenovirus Vector 155 Vaccination in Mice and Monkeys.docx by Catherine Collignon (7375037)

    Published 2020
    “…In mice, vector DNA levels gradually decreased post-immunization, but local transgene mRNA expression exhibited two transient peaks [at 6 h and Day (D)5], which were most obvious in dLNs. …”