Image 2_Activation of mechanoreceptor Piezo1 inhibits enteric neuronal growth and migration in vitro.jpeg حسب Chioma Moneme (20457845)

"…Piezo1 inhibition also led to significantly increased neuronal migration, whereas Piezo1 activation resulted in significantly decreased neuronal migration and slower neuronal recovery from injury.…"

Image 1_Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with... حسب Qing Sun (492552)

"…</p>Results<p>The TBSS analysis results showed that MHE patients had significantly decreased fractional anisotropy (FA) in the temporal part of the left superior longitudinal fasciculus and decreased kurtosis fractional anisotropy (KFA) in the left corticospinal tract and anterior thalamic radiation (p < 0.05, threshold-free cluster enhancement corrected). …"

Data Sheet 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.zip حسب Xi Luo (361139)

"…</p>Method<p>To investigate the metabolic differences, we generated four thermodynamically flux-consistent metabolic models representing the synaptic and non-synaptic (somatic) components under both control and PD conditions. …"

Image 2_Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers.tiff حسب Gaetano Zizzo (15853004)

"…</p>Methods<p>Using the computational i2b2 framework, we retrospectively analyzed data from patients admitted to internal medicine units of four hospitals in Lombardy (Italy) between January 2012 and December 2023, with a discharge diagnosis of sepsis, septic shock, or septicemia.…"

Table 1_Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease.docx حسب Xi Luo (361139)

"…</p>Method<p>To investigate the metabolic differences, we generated four thermodynamically flux-consistent metabolic models representing the synaptic and non-synaptic (somatic) components under both control and PD conditions. …"

Image 1_Activation of mechanoreceptor Piezo1 inhibits enteric neuronal growth and migration in vitro.jpeg حسب Chioma Moneme (20457845)

"…Piezo1 inhibition also led to significantly increased neuronal migration, whereas Piezo1 activation resulted in significantly decreased neuronal migration and slower neuronal recovery from injury.…"

Table 1_Evaluation of hypoxia-inducible factor-1α and urine non-transferrin-bound iron concentrations in cats with chronic kidney disease.docx حسب Chien-Hui Chen (2524213)

"…/mL in early-stage CKD cats but decreased to 8.50 pg./mL in late-stage CKD cats. uHIF-1α concentrations gradually decreased with a significant difference between the control group (44.61 pg.…"

Mitochondria-Derived Reactive Oxygen Species Regulation of Tardigrade Osmobiosis Revealed by Proteomics of Hypsibius exemplaris حسب Evan R. Stair (17803878)

"…Finally, inhibition of mitochondrial ROS significantly decreases the rate of osmobiote formation suggesting a regulation of osmobiosis through MRC-derived ROS. …"

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhea virus by phosphorylating the nucleocapsid protein حسب Zili Li (20425625)

"…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …"

Data Sheet 1_FOXA2/miR-148a-3p/SMURF2 signaling feed-forward loop alleviates spinal cord ischemia-reperfusion injury-induced neuropathic pain by modulating microglia polarization i... حسب Xiaotong Hao (20650807)

"…</p>Results<p>SCIRI significantly reduced mechanical and thermal pain thresholds in rats and promoted microglial polarization, with a concomitant decrease in SIRT1 expression and an increase in SMURF2 expression in microglial cells. …"

Data Sheet 2_FOXA2/miR-148a-3p/SMURF2 signaling feed-forward loop alleviates spinal cord ischemia-reperfusion injury-induced neuropathic pain by modulating microglia polarization i... حسب Xiaotong Hao (20650807)

"…</p>Results<p>SCIRI significantly reduced mechanical and thermal pain thresholds in rats and promoted microglial polarization, with a concomitant decrease in SIRT1 expression and an increase in SMURF2 expression in microglial cells. …"

Image 2_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"

Image 1_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"

Image 4_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"

Image 6_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"

Image 3_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"

Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... حسب Shao-jun Xu (11633956)

"…The t-AUC and DCA demonstrated that the nomograms had a better predictive value and clinical benefit rate than the American Joint Committee on Cancer (AJCC) staging. Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …"

Identifying cyst initiation candidate genes through mRNA sequencing <i>Pkd2</i> mouse kidneys at pre-cystic and early cystic time points. حسب Abigail O. Smith (11883787)

"…Colored dots indicate FDR <0.05, red indicates increased expression and blue decreased expression in Experimental vs Control. (C) The intersection between P6 DEGs (91) and P10 DEGs (5,309) includes 74 genes which we defined as cyst initiation candidates (CICs). …"

Table 1_Relationship between advanced lung cancer inflammation index and all-cause and cause-specific mortality among chronic inflammatory airway diseases patients: a population-ba... حسب Zhuanbo Luo (378365)

"…An elevated ALI was significantly related to a decreased risk of all-cause mortality, as well as mortality from cardiovascular and respiratory diseases among CIAD patients. …"

Data Sheet 2_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf حسب Bingbu Li (21097373)

"…These differentially expressed genes were significantly enriched in oxidation-reduction, ferroptosis, steroid biosynthesis, and apoptosis pathways.…"