Showing 19,501 - 19,520 results of 21,342 for search '(( significant effect decrease ) OR ( significant decrease decrease ))', query time: 0.36s Refine Results
  1. 19501

    Supplementary Material for: Endoscopic Anti-reflux Mucosal Interventions for Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Efficacy, Safety, and Compara... by figshare admin karger (2628495)

    Published 2025
    “…AET decreased at 3–6 months (P<0.001). Overall AEs occurred in 13% of cases (bleeding: 3%; stricture: 8%; dysphagia: 8%). …”
  2. 19502

    Description of the studied population (N = 710). by Maryo Baakliny (20910279)

    Published 2025
    “…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …”
  3. 19503

    Preventive measures during COVID-19 pandemic. by Maryo Baakliny (20910279)

    Published 2025
    “…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …”
  4. 19504

    Supplementary file 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

    Published 2025
    “…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…”
  5. 19505

    Data Sheet 1_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf by Lizhan Su (19936980)

    Published 2025
    “…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…”
  6. 19506
  7. 19507

    Rheological investigations of fresh fiber-reinforced cementitious composites using hydrophobic/hydrophilic UHMWPE fibers for 3D concrete printing evaluation by Yan Sun (22436)

    Published 2025
    “…Hydrophilic fibers significantly enhanced microstructural rigidity, followed by hydrophobic fibers and nanoclay, evidenced through an increase of storage modulus by 115.29%, 59.37%, and 49.49%, respectively. …”
  8. 19508

    Supplementary Material for: Gut microbiome composition and one-year survival outcomes among patients with reduced ejection fraction heart failure by figshare admin karger (2628495)

    Published 2025
    “…Results: HFrEF patients showed a significantly lower abundance of all bacterial taxa, except for A. muciniphila. …”
  9. 19509

    Tanshinone I as a novel therapeutic agent targeting von Willebrand factor-binding protein to mitigate <i>Staphylococcus aureus</i> pathogenicity by Shiyu Zhou (457967)

    Published 2024
    “…Our findings revealed that tanshinone I significantly inhibited vWbp-induced coagulation without affecting the proliferation of <i>S. aureus</i>. …”
  10. 19510

    Wheat germ agglutinin-nanoparticles encapsulating itacitinib target and suppress pro-inflammatory slan+ monocytes by Karen Alvarez (17620292)

    Published 2025
    “…Co-cultures of slan+ and slan- monocytes stimulated with LPS revealed that slan+ monocytes significantly increased HLA-DR expression.</p> <p>Results showed that slan+ monocytes from SLE patients were reduced compared to healthy controls (<i>p</i> < 0.001) and that slan+ monocytes effectively internalized WGA/F127/PNPs, unlike slan- cells. …”
  11. 19511

    Data Sheet 1_Polydopamine nanoparticles as immunomodulators: inhibition of M1 microglial polarization.docx by Maria Cristina Ceccarelli (19233688)

    Published 2025
    “…The co-treatment with PDNPs effectively mitigated these effects by reducing oxidative stress, suppressing the upregulation of M1 markers, and decreasing cytokine release, thereby preventing the shift toward a pro-inflammatory state. …”
  12. 19512

    Image 1_Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation.jpeg by Ai-Li Xu (20622440)

    Published 2025
    “…Moreover, enforced GATA4 re-expression significantly counteracted the toxic effects of ATG5 on DOX-treated hearts. …”
  13. 19513

    Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx by Lin Liu (74495)

    Published 2025
    “…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…”
  14. 19514

    Data Sheet 1_Gram-positive enhancer matrix delivering FVpE via M cell targeting elicit protective mucosal and adaptive immune responses against Helicobacter pylori infection.doc by Furui Zhang (3181935)

    Published 2025
    “…Finally, H. pylori-infected mice treated with GEM-SAM-FVpE can significantly reduce the colonization of H. pylori in gastric tissue while also decreasing gastric mucosal damage.…”
  15. 19515

    Image 3_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif by Toru Miwa (8528715)

    Published 2025
    “…This study highlights MNAM’s detrimental effects on ARHL, underscoring its significance for developing targeted approaches to delay ARHL onset and preserve auditory function.…”
  16. 19516

    Image 2_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif by Jie Chong (18433611)

    Published 2025
    “…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
  17. 19517

    Table 1_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.docx by Jie Chong (18433611)

    Published 2025
    “…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
  18. 19518

    Image 5_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif by Toru Miwa (8528715)

    Published 2025
    “…This study highlights MNAM’s detrimental effects on ARHL, underscoring its significance for developing targeted approaches to delay ARHL onset and preserve auditory function.…”
  19. 19519

    Image 1_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif by Jie Chong (18433611)

    Published 2025
    “…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
  20. 19520

    Image 2_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif by Toru Miwa (8528715)

    Published 2025
    “…This study highlights MNAM’s detrimental effects on ARHL, underscoring its significance for developing targeted approaches to delay ARHL onset and preserve auditory function.…”