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19561
Data Sheet 1_Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance protei...
Published 2025“…This study aimed to evaluate the possible synergistic effects of CHR and TMZ on glioblastoma cells in 2D- and 3D-culture models.…”
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19562
Data Sheet 1_Pharmacist-led surgical medicines prescription optimization and prediction service improves patient outcomes - a machine learning based study.docx
Published 2025“…In Phase 3, the acceptance rate of pharmacist recommendations rose to 71.3%, while the length of stay, total hospitalization costs, and medication costs significantly decreased (p < 0.05), indicating overall improvement compared to Phase 1.…”
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19563
Shikonin promotes ferroptosis though NSUN2-mediated m<sup>5</sup>C methylation modification of TFRC in acute myelocytic leukemia
Published 2025“…Overexpression of NSUN2 similarly decreased cell viability and increased cell death and ferroptosis, effects that were mitigated upon silencing of TFRC. …”
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19564
Data Sheet 1_Phyllosphere microbiome responses to nano-berberine and chemical fungicides in powdery mildew infected strawberry.pdf
Published 2025“…The results showed that nano-fungicide application significantly reduced the disease index of powdery mildew and markedly decreased its incidence in field-grown strawberries, ultimately lowering leaf disease incidence to 5.06% with a control efficacy of 96.81%. …”
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19565
Key model formula.
Published 2024“…<div><p>The COVID-19 booster immunization policy is cost-effective, but evidence on additional booster doses and appropriate strategies is scarce. …”
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19566
Model framework.
Published 2024“…<div><p>The COVID-19 booster immunization policy is cost-effective, but evidence on additional booster doses and appropriate strategies is scarce. …”
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19567
Essential model parameters.
Published 2024“…<div><p>The COVID-19 booster immunization policy is cost-effective, but evidence on additional booster doses and appropriate strategies is scarce. …”
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19568
Presentation 1_Baduanjin exercise improves functional capacity and cardiovascular function in older adults with cardiovascular diseases: a systematic review and meta-analysis.pdf
Published 2025“…What's more, it also decreased MLHFQ (MD: −7.00, 95% CI: −9.54 to −4.45, p = 0.0003, I<sup>2</sup> = 79%).…”
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19569
Image 1_The gut microbiome: a vital link to hyperuricemia, gout and acute flares?.pdf
Published 2025“…Furthermore, the gut microbiota of gout patients also exhibited significantly reduced microbial diversity compared with asymptomatic hyperuricemic patients, characterized by decreased richness of the genera Dialister, Ruminococcus, and Faecalibacterium. …”
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19570
Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc
Published 2025“…We found that both decreased and increased precipitation significantly altered the GEP (from –26% to 14%), but only decreased precipitation significantly reduced the ER and NEE (from 1% to 31%), relative to their values during natural precipitation. …”
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19571
Image 1_Huoxiang Zhengqi dropping pills alleviate exertional heat stroke–induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB pathway a...
Published 2025“…This study evaluated the protective effects of Huoxiang Zhengqi Dropping Pills (HXZQD) against EHS in a rat model. …”
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19572
Data Sheet 1_Huoxiang Zhengqi dropping pills alleviate exertional heat stroke–induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB path...
Published 2025“…This study evaluated the protective effects of Huoxiang Zhengqi Dropping Pills (HXZQD) against EHS in a rat model. …”
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19573
Table S13 from Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes
Published 2025“…<p>Categories and percent frequency of significantly decreased chromatin accessibility regions</p>…”
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19574
Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing
Published 2025“…On the contrary, increased snow depth decreased C source strength inside the exclusion offsetting the difference between reindeer grazing treatments. …”
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19575
Table 1_Weizmannia coagulans BC99 regulates oxidative stress and serum metabolic pathways to improve allergic rhinitis: a randomized, double-blind, placebo-controlled trial.docx
Published 2025“…Furthermore, BC99 supplementation significantly decreased serum IgA, complement C3, EOS, and MDA levels (p < 0.05) while enhancing antioxidant capacity (increased GSH, stabilized SOD). …”
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19576
Data Sheet 1_Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona.docx
Published 2025“…</p>Results<p>Higher concentrations in 2016–17 of IL-8 and TNF-α significantly decreased the risk of SARS-CoV-2 seropositivity in 2020–21, whereas higher concentrations of MIP-1α were a risk factor for seropositivity. …”
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19577
Table 1_Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia.docx
Published 2025“…</p><p>Results: This study demonstrated that PCPs significantly mitigated body weight loss, restored muscle fiber atrophy and mitochondrial disorder, alleviated adipose tissue wasting, strengthened the intestinal barrier integrity, and decreased the intestinal inflammation in chemotherapy-induced cachexia. …”
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19578
Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx
Published 2025“…</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. Functional investigations demonstrated that IGFBP5 downregulation exacerbated PM-induced oxidative damage, as evidenced by elevated levels of reactive oxygen species (ROS) and malondialdehyde, as well as decreased levels of superoxide dismutase 2 (SOD2). …”
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19579
Table 6_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”
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19580
CONSORT Flowchart of Participants.
Published 2025“…The intervention group showed significantly reduced weight (median; baseline 1, post-intervention 0.975, follow-up 0.983, p < 0.001), and slightly reduced waist circumference (median; baseline 1, post-intervention 0.975, follow-up 0.975, p = 0.226); however, the control group showed no change. …”