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significant effect » significant impact (Expand Search)
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significant effect » significant impact (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
effect decrease » effects decreased (Expand Search)
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12241
Mitigation of Senescence Burden in Doxorubicin-Induced Senescent Endothelial Cells by MitoQ Treatment Through Diminishing Mitochondrial ROS and DNA Damage.
Published 2025“…DOXO increased mtROS, decreased mitochondrial mass, and induced senescence. …”
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12242
DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf
Published 2024“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”
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12243
Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx
Published 2024“…Subcutaneous injection of humanized CXCL12 Ab significantly delayed AA onset in mice, and dorsal skin was analyzed. …”
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12244
Data Sheet 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12245
Data Sheet 3_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12246
Table 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.xls
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12247
Image 1_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.jpeg
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12248
Data Sheet 5_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12249
Data Sheet 2_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12250
Data Sheet 8_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12251
Data Sheet 6_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12252
Data Sheet 7_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12253
Data Sheet 4_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Background<p>Interleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. …”
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12254
DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx
Published 2024“…Pharmacokinetic parameters such as AUC<sub>0-t</sub>, C<sub>max</sub> MRT, Vd, and half-life (t<sub>1/2</sub>) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar<sup>®</sup>). …”
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12255
Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…Objective<p>To evaluate the effects and underlying mechanisms of resveratrol—a plant-derived polyphenol abundantly found in natural dietary sources such as grapes and blueberries—on the amelioration of liver fibrosis.…”
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12256
Image 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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12257
Table 4_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx
Published 2025“…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …”
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12258
Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx
Published 2025“…The incorporation of multidimensional features significantly enhanced the performance of all classification models: under multidimensional feature input, RF, SVM, DT, and KNN achieved accuracies of 96.93%, 92.44%, 90.29%, and 88.98%, respectively—all significantly outperforming models using single‐dimensional features.…”
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12259
Table 2_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.xlsx
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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12260
Data Sheet 1_Diversity, functionality, and stability: shaping ecosystem multifunctionality in the successional sequences of alpine meadows and alpine steppes on the Qinghai-Tibet P...
Published 2025“…Surprisingly, community stability also significantly influences ecosystem multifunctionality—a factor rarely highlighted in previous studies. …”