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lower decrease » larger decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
significant effect » significant impact (Expand Search)
effect decrease » effects decreased (Expand Search)
linear decrease » linear increase (Expand Search)
lower decrease » larger decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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12461
Image_1_Differential microbiome features in lake–river systems of Taihu basin in response to water flow disturbance.pdf
Published 2024“…Additionally, migration and dispersal rates of microbes in the ET region, along with the impact of dispersal limitations, were significantly higher than in the ST region. High flow disturbances notably reduced microbial niche width and overlap, decreasing the complexity and stability of microbial coexistence networks. …”
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12462
Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx
Published 2025“…</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. Functional investigations demonstrated that IGFBP5 downregulation exacerbated PM-induced oxidative damage, as evidenced by elevated levels of reactive oxygen species (ROS) and malondialdehyde, as well as decreased levels of superoxide dismutase 2 (SOD2). …”
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12463
Table 6_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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12464
CONSORT Flowchart of Participants.
Published 2025“…To address obesity in adults with severe intellectual disabilities who are highly dependent, we developed the “Conflict-Free Weight Loss Program for Adults with Severe ID and Autism” to support their mothers and piloted the program, and the results showed that it was effective for weight loss. This study aimed to determine the feasibility of day center nurses and dieticians implementing the “Conflict-Free Weight Loss Program for Adults with Severe ID and Autism” and whether this would support effective weight loss in adults with severe intellectual disabilities, both with and without autism. …”
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12465
Data Sheet 1_MgSO4 alleviates hippocampal neuroinflammation and BBB damage to resist CMS-induced depression.docx
Published 2025“…Purpose<p>Magnesium sulfate (MgSO<sub>4</sub>) possesses the advantages of being readily accessible, cost-effective, and having low toxicity. It has potential applications as a neuroprotective agent. …”
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12466
Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste...
Published 2025“…This study investigates the long-term effects of 8 years of GM application combined with plow tillage on soil microbial communities and physicochemical properties under a peanut monocropping system. …”
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12467
Image 1_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg
Published 2025“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”
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12468
<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b>
Published 2025“…The 4-week AngII group exhibited significantly increased fibrosis (~2-fold vs. Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …”
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12469
Table 1_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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12470
Table 4_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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12471
<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b>
Published 2025“…Side effects were limited to benign gastrointestinal symptoms. …”
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12472
Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Antiviral and immunomodulatory effects were assessed by quantitative RT-PCR and analysis of inflammatory markers, including interferon-stimulated genes (MX1, IFI44L, IFN-β) and cytokines (IL-1β, TNF-α). …”
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12473
Table 3_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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12474
Image 2_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg
Published 2025“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”
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12475
Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Antiviral and immunomodulatory effects were assessed by quantitative RT-PCR and analysis of inflammatory markers, including interferon-stimulated genes (MX1, IFI44L, IFN-β) and cytokines (IL-1β, TNF-α). …”
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12476
Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Antiviral and immunomodulatory effects were assessed by quantitative RT-PCR and analysis of inflammatory markers, including interferon-stimulated genes (MX1, IFI44L, IFN-β) and cytokines (IL-1β, TNF-α). …”
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12477
A platform for the rapid screening of equine immunoglobins F (ab)2 derived from single equine memory B cells able to cross-neutralize to influenza virus
Published 2024“…Antibody H81 exhibited the highest cross neutralizing activities against EIV strains <i>in vitro</i>. Furthermore, it effectively protected EIV-challenged mice, resulting in significantly improved survival, reduced pulmonary inflammation and decreased viral titers. …”
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12478
Table 2_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…In this study, we investigated the effects of ESD on four major tissues of the lobster (testis, intestine, hepatopancreas, and green gland) using transcriptomic analysis. …”
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12479
Characteristics of specialists at day centers.
Published 2025“…To address obesity in adults with severe intellectual disabilities who are highly dependent, we developed the “Conflict-Free Weight Loss Program for Adults with Severe ID and Autism” to support their mothers and piloted the program, and the results showed that it was effective for weight loss. This study aimed to determine the feasibility of day center nurses and dieticians implementing the “Conflict-Free Weight Loss Program for Adults with Severe ID and Autism” and whether this would support effective weight loss in adults with severe intellectual disabilities, both with and without autism. …”
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12480
Data Sheet 1_A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure.docx
Published 2025“…NMEG-CGRP administration significantly attenuated these TAC-induced adverse cardiac effects in the HF mice.…”