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161
Intracutaneous ALA photodynamic therapy
منشور في 2011"…Low doses (≤0.016%) targeted fat; producing fat necrosis with minimal inflammation, manifested both clinically and histologically. …"
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162
Extent and Mitigation of Financial Toxicity of Immune Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma
منشور في 2025"…This challenge is particularly severe in LMICs, where the high incidence of HCC is compounded by the unaffordability of effective treatments, creating a significant barrier to care. …"
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163
Trans-resveratrol-loaded nanostructured lipid carrier formulations for pulmonary drug delivery using medical nebulizers
منشور في 2025"…Moreover, the air jet nebulizer exhibited significantly higher emitted dose (ED) (87.44 ± 3.36%), fine particle dose (FPD) (1652.52 ± 9.68 µg) fine particle fraction (FPF) (36.25 ± 4.26%), and respirable fraction (RF) (93.41 ± 4.03%) when the F1 formulation was used as compared to the F2 formulation. …"
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164
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
منشور في 2025"…Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …"
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165
Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
منشور في 2023"…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …"
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166
Olodaterol for the treatment of chronic obstructive pulmonary disease
منشور في 2016"…Other clinical trials demonstrated that olodaterol produced beneficial effects on FEV1 measures throughout the 24-hour dosing interval. …"
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167
Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor–induced hepatotoxicity is mediated by Kupffer cells
منشور في 2004"…DT388GMCSF, a fusion toxin composed of the NH2-terminal region of diphtheria toxin (DT) fused to human granulocyte-macrophage colony-stimulating factor (GMCSF) has shown efficacy in the treatment of acute myeloid leukemia. However, the primary dose-limiting side effect is liver toxicity. We have reproduced liver toxicity in rats using the rodent cell-tropic DT-murine GMCSF (DT390mGMCSF). …"
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168
Activation of K<sub>v</sub>7 channels with the anticonvulsant retigabine alleviates neuropathic pain behaviour in the streptozotocin rat model of diabetic neuropathy<sub>v</sub>7 c...
منشور في 2019"…Retigabine given at a dose of 15 mg/kg (but not at 7.5 mg/kg, i.p.) significantly attenuated mechanical, but not heat hypersensitivity in DPNP rats, and was as effective as the positive control gabapentin. …"
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169
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…In conjunction with these data, whole-cell electrophysiological studies revealed that this concentration had maximum effect on membrane potentials, conductance and currents. …"
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170
Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine
منشور في 2020"…The aim of the study was to evaluate the effect of chronic low-dose Cd on vascular structure and function. …"
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171
Trends of acetaminophen overuse among ambulatory patients in Lebanon
منشور في 2016"…Acetaminophen (APAP), also known as paracetamol, is used by millions of people worldwide for its antipyretic and analgesic properties. At therapeutic doses, APAP is effective and safe. However, the long-term use and the ingestion of inappropriately high doses pose substantial risks to APAP users. …"
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172
Alpelisib Therapy in 2 Patients With Congenital Hyperinsulinism
منشور في 2025"…This allowed for the tapering and discontinuation of other medications (diazoxide and octreotide) and facilitated a transition to bolus gastrostomy-tube/oral feeding. No significant adverse effects were reported. Alpelisib shows promise as both an adjunctive and primary therapy for CHI, improving glucose levels and reducing dependence on continuous feeding and other medications. …"
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173
Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis
منشور في 2025"…In ACG patients, the pooled effect showed a percentage of IOP reduction (IOPR%) of 35.22% with a mean IOP reduction of −9.51 mmHg, <i>p</i>< 0.001 at 12 months, and an IOPR% of 27.47% with a mean reduction of −6.37 mmHg, <i>p</i> < 0.001 at 24 months. …"
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174
Differential water quality in confined and free-flowing water bodies, Lebanon
منشور في 2003"…Statistical analysis of the data revealed significant differences in water quality. The differences could be attributed to the fact that whereas the Qaraaoun reservoir is receiving domestic waste discharges that lead to an increase in the CO2 content and a pH decrease, the Nahr-Ibrahim River is influenced by agricultural runoffs and industrial discharges that increase the pH values. …"
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175
Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
منشور في 2019"…BRMUS factors, such as fatigue, depression, and anger, significantly decrease in the enhancement group compared to vigilance group. …"
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176
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. …"
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177
Smart Synthesis of Trimethyl Ethoxysilane (TMS) Functionalized Core–Shell Magnetic Nanosorbents Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>: Process Optimization and Application fo...
منشور في 2020"…Pareto chart of standardized effects together with analysis of variance (ANOVA) at 95.0 confidence interval (CI) were used to determine statistically significant variable(s). …"
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178
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…Development of new, effective therapies for metastatic melanoma that target novel pathways associated with the genesis of metastatic disease is a major unmet clinical need. …"
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179
Examining depression, antidepressants use, and class and their potential associations with osteoporosis and fractures in adult women: Results from ten NHANES cohorts
منشور في 2024"…<h3>Introduction</h3><p dir="ltr">Osteoporosis, a significant public health concern, affects millions of adult women globally, leading to increased morbidity and fracture risk. …"
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180
Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting
منشور في 2025"…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …"