Clinical relevance of aortic stiffness in end-stage renal disease and diabetes : implication for hypertension management by Bahous, Sola Aoun

“…Aortic stiffness represents a marker of structural but also functional arterial damage associated with increased pressure pulsatility. Carotid–femoral pulse wave velocity (cf-PWV), as a marker of aortic stiffness, may provide a readily available information for the effectiveness of risk reduction strategies. …”
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Lipsome-coated metal organic frameworks as a new drug nanocarrier by Mohamed, Omnia A.

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A Multidecadal Assessment of Drought Intensification in the Middle East and North Africa: The Role of Global Warming and Rainfall Deficit by Ahmed El Kenawy (7510103)

“…Spatially, the SPEI highlighted significant drought intensification in temperate and cold desert (CWb, BWk) zones across the region, primarily driven by increasing air temperatures. …”

Lead exposure of Bangladeshi women at childbearing age: Does mother's education reduce fetal risk factors? by Sharmind Neelotpol (19732277)

“…This indicated that their knowledge or awareness of lead, particularly its sources and detrimental effects, remained superficial, and their educational background had no statistically significant difference with respect to the awareness of lead toxicity (<i>p</i> = 0.103). …”

The Integration of Agile Methodology in the Development of Software Project by ALMHEIRI, MOHAMMED

“…Agile proponents have produced a number of assertions regarding the advantages of agile approaches, such as increased group productivity and effectiveness, improved software reliability, and business effectiveness. …”
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials by Pieter Francsois, Fouche

“…No compelling evidence of increased vascular occlusive events emerged (OR 0.96, 95% CI 0.73 to 1.27). …”
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Narratives of internal migration experiences, health/well-being issues among females working as head-porters (Kayayei) in Ghana by Kuyini, Ahmed Bawa

“…Findings– The results revealed the geographic, structural and family issues that promote increased migration of females to the cities. The findings betray the potential negative effects of migration on the participants’ quality of life, including accessing health services. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Potential Medical Applications of Chitooligosaccharides by Sukumaran Anil (14158935)

“…COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. …”

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). Concomitantly, we detected increased levels of LAMP-1 (a marker of lysosomal homeostasis) and LAMP-2A (a key marker of CMA). …”

Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties by Maneera Y Aljaber (18278971)

“…Conclusion: In the short term, 20-hydroxyecdysone mediates CYP17A1 downregulation without a significant increase in plasma progesterone, which has a vasodilatory effect involving inhibition of voltage-dependent calcium channels, and the potential to enhance 20-hydroxyecdysone vasorelaxation.…”

Diabetes mellitus and renal failure by Aoun, S.

“…Diabetes mellitus and end-stage renal disease are two pathologic entities associated with increased cardiovascular risk. Several studies have shown that arterial stiffness is increased in both cases and contributes to the increased risk. …”
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How does varying the number of personas affect user perceptions and behavior? Challenging the ‘small personas’ hypothesis! by Joni Salminen (7434770)

“…Our study results from eye-tracking and survey data suggest that when using interactive persona systems, the number of personas can be increased from the conventionally suggested ‘less than ten’, without significant negative effects on user perceptions or task performance, and with the positive effects of increasing engagement with the personas, having a more diverse representation of the end-user population, as well as users accessing personas from more varied demographic groups for a design task. …”

Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…We also investigated correlations between the levels of different CD4⁺ T cell subsets and the clinicopathologic features including disease stage and tumor budding. We found a significant increase in the levels of CD4⁺FoxP3⁺Helios⁺ T cells, which represent potentially highly immunosuppressive Tregs, in the CRC TME. …”

Can salespeople use social media to enhance brand awareness and sales performance? The role of manager empowerment and creativity by Kalra, Ashish

“…The relationship between social media and brand awareness is magnified with the increase in salesperson creativity. Findings also show that manager empowerment increases salesperson creativity. …”
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Obesity and menopause by Albert A. Opoku FRCOG (15955340)

“…Increasing life expectancy means women spend a significant part of their lives in the menopause. …”

Eradication of hepatitis C virus infection in kidney transplant recipients using direct‐acting antiviral therapy: Qatar experience by Mohamad M. Alkadi (14778640)

“…In the pre-direct-acting antiviral (DAA) era, treatment of HCV infection was associated with low response rates, poor tolerance, and increased risk of allograft rejection. However, DAAs have revolutionized HCV treatment. …”

Engineering the Surface and Mechanical Properties of Water Desalination Membranes Using Ultralong Carbon Nanotubes by Yehia M. Manawi (18091207)

“…The water flux of the fabricated membranes increased considerably (up to 20 times) along with the increase in CNT loading. …”

Natural products as chemo-radiation therapy sensitizers in cancers by Sabah Nisar (12561961)

“…Unfortunately, treatment failure due to intrinsic and acquired resistance to the current CT and RT is a significant challenge associated with poor patient prognosis. …”

<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells by Nouralhuda Alateyah (21363215)

“…Interestingly, apoptosis was mediated by a significant loss of mutant p53 protein, and increased Bax/Bcl2 ratio. …”