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effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant effects » significant effect (Expand Search), significantly affected (Expand Search)
effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
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17481
BrdU assay in control siRNA (blue bars) and in PAX6 knockdown (red bars) limbal epithelial cells (LECs) without and after 1µM or 5µM RA incubation for 48 hours.
Published 2025“…<p>Two-way ANOVA, followed by Dunnett’s test was used. Significant p values (<0.05) are highlighted. BrdU assay shows a significantly lower proliferation rate in the PAX6 siRNA knockdown group than in control siRNA group (p < 0.001). 5µM RA treatment significantly decreased proliferation rate in controls (p = 0.025). …”
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17482
Image 3_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.png
Published 2025“…</p>Results<p>ET patients demonstrated significant tremor improvement at the treated hand, which persisted throughout the 1-year study period. …”
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17483
Table 1_The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and pulmonary function: evidence from NHANES 2007–2012.docx
Published 2025“…</p>Results<p>The results manifested a significant correlation between decreased FEV1 and FVC values and elevated NHHR, most notably within the highest quartile of NHHR (Q4), where the association was most pronounced. …”
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17484
Table 1_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.docx
Published 2025“…</p>Results<p>ET patients demonstrated significant tremor improvement at the treated hand, which persisted throughout the 1-year study period. …”
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17485
<b>Metabolic flux analysis revealed </b><b>key roles of </b><b>ArcB</b><b> in ADI pathway and IlvC in BCAA </b><b>biosynthesis </b><b>during </b><b><i>Streptococcus suis</i></b><b>...
Published 2025“…Transcriptome analysis found a significant suppression of many central metabolic genes during anaerobic growth of <i>S. suis</i>. …”
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17486
Supplementary file 1_Analysis of gut and circulating microbiota characteristics in patients with liver cirrhosis and portal vein thrombosis.docx
Published 2025“…</p>Results<p>(1) Gut microbiota showed no α-diversity difference between groups, but β-diversity differed significantly. PVT patients had increased Gram-negative bacteria (such as Escherichia-Shigella) and decreased SCFA-producing taxa. (2) Compared with peripheral vein microbiota, portal vein microbiota showed significant difference in α diversity and β diversity in cirrhotic patients with PVT, with Massilia enriched. (3) Portal microbiota had the highest diagnostic value for PVT (AUC = 0.95). (4) The tPVT group had more portal-feces shared genera than the tNPVT group (49 vs. 29). …”
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17487
Data Sheet 1_Global, regional, and national burden and trends of intracerebral hemorrhage among adolescents and young adults aged 15–39 years from 1990 to 2021: a comprehensive tre...
Published 2025“…Background<p>Intracerebral hemorrhage (ICH) poses a significant health challenge, notably affecting adolescents and young adults (AYAs) aged 15–39 years. …”
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17488
Image 2_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.png
Published 2025“…</p>Results<p>ET patients demonstrated significant tremor improvement at the treated hand, which persisted throughout the 1-year study period. …”
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17489
Image 1_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.jpeg
Published 2025“…</p>Results<p>ET patients demonstrated significant tremor improvement at the treated hand, which persisted throughout the 1-year study period. …”
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17490
Flow cytometry
Published 2025“…Flow cytometry results showed that compared with normal cells, there was no significant difference in apoptosis rate after transfection of mimics NC and inhibitor NC, but significantly increased apoptosis rate after transfection of miR-126-3p inhibitor and significantly decreased apoptosis rate after transfection of miR-126-3p inhibitor.…”
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17491
supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma
Published 2025“…(middle): Effects of MYLK4 knockdown in AD-RD cells. siMYLK4 treatment reduced self-renewal capacity and decreased SALL2 and pT43-CDKAL1 protein levels. …”
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17492
Image 3_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…This study highlights MNAM’s detrimental effects on ARHL, underscoring its significance for developing targeted approaches to delay ARHL onset and preserve auditory function.…”
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17493
Table 1_Working like a mule? The physiological toll of heavy loads on mules.docx
Published 2025“…Conversely, glutathione peroxidase (GPx) activity decreased as load increased, implying increased oxidative demand. …”
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17494
SPIRIT Schedule of Enrollment.
Published 2025“…</p><p>Results</p><p>The EX group showed increased EMG activation for the tibialis anterior, gastrocnemius medialis, rectus femoris, and biceps femoris in both anterior-posterior (2.23 MVIC%, 95% CI: 1.13 to 3.34, p < 0.001) and posterior-anterior directions (2.35 MVIC%, 95% CI: 1.80 to 2.91, p < 0.001) compared to CO group. Onset time decreased significantly in the EX group relative to CO group (anterior-posterior: -108.07 ms, 95% CI: -117.23 to -98.89, p < 0.001; posterior-anterior: -98.72 ms, 95% CI: -106.54 to -90.90, p < 0.001). …”
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17495
Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway
Published 2025“…The NF-κB inhibitor Bay11-7082 reduced the activation of the NF-κB/Wnt5a-ROR2 pathway and the inflammatory response; the application of PCG significantly augmented this inhibitory effect.</p> <p>PCG demonstrated an anti-inflammatory effect in LPS-induced DPCs by targeting the NF-κB/Wnt5a-ROR2 signaling pathway.…”
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17496
Image 5_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…This study highlights MNAM’s detrimental effects on ARHL, underscoring its significance for developing targeted approaches to delay ARHL onset and preserve auditory function.…”
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17497
Table 1_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.xlsx
Published 2025“…</p>Results<p>Histopathological analysis, serum biochemical tests, and ELISA measurements showed that QgYp effectively decreased the levels of ALT, AST, HA, LN, PCIII, and IV-C while improving collagen deposition and hepatocyte necrosis. …”
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17498
Data Sheet 1_Response of alfalfa growth and rhizosphere properties to soil phosphorus supply and mowing in a salt-affected soil.docx
Published 2025“…Furthermore, mowing significantly reduced rhizosphere carboxylates concentration (30.4%-100%) and APase activity (39.8%-75.0%) across all P treatments. …”
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17499
Measuring muscle strength [49].
Published 2025“…</p><p>Results</p><p>The EX group showed increased EMG activation for the tibialis anterior, gastrocnemius medialis, rectus femoris, and biceps femoris in both anterior-posterior (2.23 MVIC%, 95% CI: 1.13 to 3.34, p < 0.001) and posterior-anterior directions (2.35 MVIC%, 95% CI: 1.80 to 2.91, p < 0.001) compared to CO group. Onset time decreased significantly in the EX group relative to CO group (anterior-posterior: -108.07 ms, 95% CI: -117.23 to -98.89, p < 0.001; posterior-anterior: -98.72 ms, 95% CI: -106.54 to -90.90, p < 0.001). …”
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17500
Data Sheet 1_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.docx
Published 2025“…</p>Results<p>Histopathological analysis, serum biochemical tests, and ELISA measurements showed that QgYp effectively decreased the levels of ALT, AST, HA, LN, PCIII, and IV-C while improving collagen deposition and hepatocyte necrosis. …”