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18141
Table 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.docx
Published 2025“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”
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18142
Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation
Published 2025“…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …”
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18143
Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
Published 2025“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”
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18144
Table 1_The real-world safety of Nivolumab: a pharmacovigilance analysis based on the FDA adverse event reporting system.docx
Published 2025“…The most frequently reported AEs included fatigue, dyspnea, musculoskeletal pain, decreased appetite, cough, nausea, and constipation. …”
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18145
Table 1_Age-related lung structure changes by quantitative assessment: a cross-sectional study in a Chinese male cohort.docx
Published 2025“…</p>Conclusion<p>Lung aging is not a linear process, and the lung structural alterations in the upper and lower lobes exhibit significant heterogeneity.</p>…”
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18146
Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif
Published 2025“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”
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18147
Image 3_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St...
Published 2025“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”
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18148
Image 1_Temporal trends of community and climate changes in the anthropocene: 21-year dynamics of four major functional groups in a rocky intertidal habitat along the Pacific coast...
Published 2025“…We aimed to examine the 21-year trends in regional abundance at both functional-group and species levels, plus their driving mechanisms and their dependence on species properties (thermal niche, calcification status, and vertical niche). Significant temporal trends in abundance were detected at functional-group levels for benthic algae (increasing) and herbivores and carnivores (both decreasing); they followed the temporal population trends of the dominant species. …”
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18149
Data Sheet 4_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Metabolite analysis revealed associations between decreased proline, isoleucine, valine, and alanine levels with IS. …”
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18150
Image 2_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disease St...
Published 2025“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”
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18151
Presentation 1_Granola consumption with multiple prebiotics in Japanese participants increases Bifidobacterium abundance and improves stress and subjective sleepiness.pptx
Published 2025“…</p>Results<p>After 8 weeks, subjective insomnia scores and sleep onset and maintenance improved significantly, whereas the stress and mood disturbance scores decreased significantly. …”
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18152
Data Sheet 2_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disea...
Published 2025“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”
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18153
Table 1_Temporal trends of community and climate changes in the anthropocene: 21-year dynamics of four major functional groups in a rocky intertidal habitat along the Pacific coast...
Published 2025“…We aimed to examine the 21-year trends in regional abundance at both functional-group and species levels, plus their driving mechanisms and their dependence on species properties (thermal niche, calcification status, and vertical niche). Significant temporal trends in abundance were detected at functional-group levels for benthic algae (increasing) and herbivores and carnivores (both decreasing); they followed the temporal population trends of the dominant species. …”
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18154
Differential neural dynamics in the GNP model incorporating electrodiffusion and ion concentration changes.
Published 2025“…(f) The harmonic means of intramembrane potassium and chloride concentrations increase, whereas for sodium, it decreases during neural activity. (g-l): ion-concentration dependent activity. …”
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18155
Soil carbon, nitrogen, and phosphorus stoichiometry in subtropical forests of Zhejiang, China
Published 2025“…TP content increased and C:P ratio decreased monotonically with latitude, which supports the soil substrate age hypothesis. …”
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18156
Supplementary file 1_Changes of potential shorty-chain fatty acids producing bacteria in the gut of patients with spinal cord injury: a systematic review and meta-analysis.zip
Published 2025“…Firmicutes and Lactobacillus decreased. In the chronic phase, Firmicutes decreased in the SCI group. …”
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18157
Image 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif
Published 2025“…Clinicopathologic characteristics were significantly correlated with risk scores. There were significant differences in the proportion of tumor-infiltrating immune cells, the TP53 mutation rate, the expression of immune checkpoint-related genes, and IC50 of the chemotherapeutic drugs between the low- and high-risk groups. …”
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18158
Image 1_Unveiling the intricacies: small interfering RNA targeting Snail-1 unravels dynamics in endometrial carcinoma cell behavior.jpeg
Published 2025“…Moreover, transfection correlated with increased apoptosis and decreased migration of treated HEC-1A cells.</p>Conclusion<p>The study emphasizes the significant influence of Snail-1 on EMT in EC cells, thereby impacting apoptosis and metastasis. …”
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18159
Table 1_Multiparametric MRI assessment of renal blood oxygenation, fat content, and hemodynamics in an animal model of metabolic dysfunction-associated steatotic liver disease.docx
Published 2025“…Compared with those at week 14, renal T2* significantly decreased at week 20, FF increased at week 20, and serum creatine levels increased at week 24. …”
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18160
Table 6_The SlERF4-9-SlCDF1/3-SlAEC2/SlPIN5 module regulates tomato root morphogenesis.xlsx
Published 2025“…The fresh weight, drought weight, number of primary lateral roots (LRs), average root diameter, and number of root tips were also decreased in the mutant. The findings suggest that SlERF4-9 plays a significant role in root growth and development. …”