Image 6_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff by Tien Le (634791)

“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”

Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr... by Zemmar A. (11259339)

“…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …”

Data Sheet 1_Divergent profiles of rhizosphere soil carbon and nitrogen cycling in Pinus massoniana provenances with different types of carbon storage.docx by Zichen Huang (6587885)

“…</p>Results<p>Our findings revealed a significant increase in the relative abundance of Acidobacteriota and Ascomycota by 23 and 61%, respectively, whereas Basidiomycota significantly decreased by 8% in the rhizosphere of P. massoniana provenances with high carbon storage compared with those with low carbon storage. …”

Supplementary file 1_Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms.docx by Safiya Al Yazeedi (22075034)

“…<p>Mechanical strain plays a significant role in lung pathophysiology. Current two-dimensional (2D) in vitro models fail to capture the lung's dynamic mechanical environment. …”

Image2_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Table2_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.xlsx by Vineeta Pandey (10043698)

“…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …”

Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf by Man Zhao (314232)

“…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …”

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy by Tanvi Chokshi (12970453)

“…There was no significant difference between aqueous RBP3 levels in those with type 1 or type 2 diabetes. …”

Divergent gene expression in <i>D. sechellia.</i> by Daehan Lee (5043377)

“…<p><b>(A)</b> Histogram of the frequency of <i>D. sechellia</i>-specific DEGs across 94 cell types, arranged by decreasing DEG number. The remaining 13 cell types with no DEGs are not shown. …”

Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Table_3_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.DOCX by Ling Li (38566)

“…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …”

Table 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.docx by Guanfei Zhao (3815596)

“…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …”

Table 1_Integrated analysis of serum metabolomics and fecal microbiome in infants with necrotizing enterocolitis.docx by Zhi-ying Lin (12997350)

“…Serum metabolomics identified significantly decreased ornithine, DL-arginine, L-threonine, leucine, and D-proline in NEC-D versus non-NEC. …”

DataSheet3_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Data Sheet 1_Individualization of clinical target volume delineation in eccentric nasopharyngeal carcinoma: a prospective comparative study.docx by Yunrui Song (10672668)

“…</p>Results<p>Our results showed that compared with conventional CTV, the volume of CTV decreased significantly (P< 0.05) through individualizing delineation for eccentric NPC, especially CTV1 volume (95.81 cm³ vs. 57.57 cm³, P < 0.001). …”

Table 6_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.xlsx by Tien Le (634791)

“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”

Image2_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Data Sheet 1_Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai.xlsx by Xingxing Yin (7919447)

“…</p>Results<p>The number of older adult care institutions in Shanghai has seen significant growth over the past 20 years, increasing fourfold due to the rise in both public and private facilities. …”

Video 1_How can the left atrial strain be correctly determined by cardiovascular magnetic resonance feature tracking?.mp4 by Rehsan Akkuzu (20963705)

“…</p>Conclusion<p>Optimized LA planning procedure for assessment of the longest LA dimensions results in significant alterations in CMR quantifications with increased chamber volumetrics and decreased strain and strain rates compared to standard procedure.…”