Utilization of lactate trajectory models for predicting acute kidney injury and mortality in patients with hyperlactatemia: insights across three independent cohorts by Yipeng Fang (14132676)

“…When compared with the Traj-3, Traj-2 was only significantly associated with the decreased risk of hospital mortality (OR 0.17, 95% CI 0.14–0.20, <i>p</i> < 0.001), but no with the likelihood of AKI development (OR 0.90, 95% CI 0.77–1.05, <i>p</i> = 0.172). …”

Image 2_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif by Yujuan Wu (2249857)

“…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”

Data Sheet 1_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.csv by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Image 8_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

<b>Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor, </b><b><i>Bcl6</i></b> by Dudley H. McNitt (20208081)

“…T follicular helper (Tfh) cells are increased in type 1 diabetic individuals and alterations in Tfh-like cells in the peripheral blood predicted individual responses to abatacept. …”

Data Sheet 1_Biological mechanisms of sodium nitroprusside in enhancing quality of Radix Paeoniae Rubra and Radix Paeoniae Alba.docx by Kai Zhao (53042)

“…Moreover, experiments involving combined treatment with SNP and ROS scavengers demonstrated that ROS act as the key mediator linking exogenous NO to the secondary metabolism of P. lactiflora: scavenging ROS significantly attenuated the SNP-induced accumulation of target secondary metabolites.…”

Image 11_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Image 3_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Table 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx by Nikola Habek (21178259)

“…In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…”

Supplementary Material for: Role of Raf Kinase Inhibitor Protein in Modulating Echinococcal Cyst Fluid-induced Degranulation in Bone Marrow-Derived Mast Cells by figshare admin karger (2628495)

“…Following sensitization, BMMCs from the KO group demonstrated significantly higher degranulation rates compared to the WT group (p < 0.05). …”

Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx by Ke He (331344)

“…The centroid ratio slightly decreased with increasing DBH, indicating that larger trees tend to have more ovate leaves than elliptical leaves. …”

Spectral shift of fluorophore NHS-esters. by Hyunwoo Kim (690467)

“…After 5 min of illumination with a 561-nm excitation laser, the fluorescence signal in the 647-nm detection channel decreased, while the signal in the 561-nm detection channel significantly increased, indicating a spectral blue-shift of the emission spectrum. …”

<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... by Silvia Torchio (611349)

“…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca²⁺ fluxes due to altered transcription of Ca²⁺-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …”

Table 5_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Image 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf by Juanjuan Zhang (432819)

“…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …”

Table 4_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”

Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx by Xinxin Li (281237)

“…</p>Results<p>Our findings revealed that the expression of SMAD4 is decreased in NK cells within the TME of human CRC. …”

Image 3_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif by Yujuan Wu (2249857)

“…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”