Urtica dioica extract and its impact on blood lipids, glycemia & inflammation in the rat model. (c2005) حسب Baroudy, Karmen George

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Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie حسب Echtay, Akram

"…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …"
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Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting حسب Ananth Nazarene (21239912)

"…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …"

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman, Alzu'bi

"…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies حسب Umar Nawaz Kayani (17131781)

"…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …"

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman Alzu'bi (18192898)

"…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"

Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism حسب Tarek Fouda (18472476)

"…</p><h3>Conclusion</h3><p dir="ltr">The conversion of Cinacalcet to Etelcalcetide in HD patients with secondary hyperparathyroidism resulted in a significant improvement in PTH level. It was well tolerated by patients with no reported side effects.…"

Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review حسب Maged S. Alhammadi (14150757)

"…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …"

The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention حسب Almonzer Al-Qiami (22393303)

"…This leads to a rapid increase in parasympathetic activity, resulting in a decrease in heart rate (HR) and blood pressure, which can potentially lead to bradycardia, and cardiac arrest, with a prevalence of 14.5% during neurointerventional procedures (8). …"

Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review حسب Hamid El Bilali (15864930)

"…Effects on food utilization are mainly seen in the decrease in diet quality and dietary diversity. …"

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…Results: When applied separately, topotecan and andrographolide both exhibited anti-proliferative effects in a dose-dependent manner. Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. …"
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults حسب Khaddaj, Rashel

"…Furthermore, the change between both groups was significantly different (-7.61 ±4.03 in the Vitamin D group, -3.50±1.54 in the control group; p=<0.001) Conclusion: The present study shows thata 50.000 IU/week dose of vitamin D supplementation for 3 months was enough to increase vitamin D levels beyond sufficient and decrease depression symptoms in Saudi Arabian Adults. …"
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Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses حسب Merilyn Lock (9440240)

"…After sub-grouping, significant differences were present for PPO where the effect size was higher for well-trained women (g = 0.37) compared with well-trained men (g = 0.17), and for V̇ O_2max where interventions with a duration of 4 weeks or less had significantly smaller effect sizes compared with those longer than 4 weeks (p < 0.001). …"

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …"

Local arterial vasoconstriction induced by octreotide in patients with cirrhosis حسب Chatila, Rajaa

"…FBF in the control arm was unchanged despite a significant decrease in systemic glucagon levels. Methacholine infusion increased FBF around 300%, which was not altered by the concomitant infusion of octreotide. …"
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills حسب Abbas, Tariq

"…While video evaluations did not detect significant changes, EMG data provided measurable differences in skill acquisition, suggesting that wearable sensors could enhance objective evaluations of surgical proficiency in residency programs.…"
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Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …"

Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain حسب Mohamed H. M. Ali (5768066)

"…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …"

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function حسب Sahar I. Da'as (17128747)

"…We recently showed that four arrhythmogenic CaM mutations (N98I, D132E, D134H, and Q136P) significantly reduce the binding of CaM to RyR2. Herein, we investigate in vivo functional effects of these CaM mutations on the normal zebrafish embryonic heart function by microinjecting complementary RNA corresponding to CaMN98I, CaM^D132E, CaM^D134H, and CaM^Q136P mutants. …"