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significant event » significant effect (Expand Search), significant level (Expand Search), significant effects (Expand Search)
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3141
Table 1_Inner engineering is associated with perceived improvements in relationship quality, interpersonal connections, and interpersonal compassion.docx
Published 2024“…The following measures were used: the Positive-Negative Relationship Quality (PN-RQ) scale, Interpersonal Mindfulness Scale (IMS), Perceived Stress Scale (PSS), Compassion Scale (CS), and Flourishing Measure. Linear mixed-effects models were used to analyze the survey data, with p-values of < 0.05 considered statistically significant.…”
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3142
Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus
Published 2025“…Lyn levels negatively correlated with SLEDAI and 24-hour urine protein (24h-U-pro) while positively correlated with serum C3, C4, hemoglobin, and albumin. Multiple linear regression indicated an independent association between Lyn mRNA and SLEDAI. …”
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3143
Table 1_Association of rs440446 in the APOE intron region with multidimensional cognitive function, lipid/metabolic markers, and spontaneous neural activity in Chinese urban commun...
Published 2025“…Neuropsychological tests, lipid/metabolic markers (n = 326), and resting-state fMRI (rs-fMRI) data (n = 216) were collected. Multivariable linear regression was used to assess associations between rs440446 and cognitive performance, lipids, and metabolic indicators. …”
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3144
Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX
Published 2024“…Weighted multivariate linear models, restricted cubic spline (RCS), and subgroup analysis were subsequently carried out to evaluate the influence of PHDI on biological aging.…”
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3145
Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip
Published 2025“…Notably, highly expressed proteins in horse milk were closely linked to immune signaling pathways, functioning as immune modulators. …”
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3146
Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca...
Published 2024“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”
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3147
DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co...
Published 2024“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”
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3148
DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co...
Published 2024“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”
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3149
Multi-Omics Insights into Microbiome and Metabolite Signatures as Potential Biomarkers for Feline Hypertrophic Cardiomyopathy
Published 2025“…Compared to healthy cats, those with HCM exhibited significant gut microbiota dysbiosis, including decreased abundances of <i>Campilobacterota</i>, <i>unclassified_k_norank_d_Bacteria</i>, <i>Blautia</i>, <i>Helicobacter</i>, and <i>Ruminococcus_torques_group</i>, while <i>Romboutsia</i> and <i>Lactococcus</i> were enriched in the HCM group. …”
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3150
Image 1_Bright light exposure reduces negative affect and modulates EEG activity in sleep-deprived and well-rested adolescents.tif
Published 2025“…</p>Results<p>Bright light significantly reduced negative affect and improved Digit Span Forward task performance. …”
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3151
Data Sheet 1_Microbiome-metabolome dysbiosis of bronchoalveolar lavage fluid of lung cancer patients.docx
Published 2025“…Metabolites increased in lung cancer were Citric acid, N-Acetylneuraminic acid, Oxoglutaric acid, and Neopterin, whereas L-Tryptophan, Uridine, 3-Hydroxybutyric acid decreased. The KEGG pathways suggest a significant link between microbial presence and both tumorigenesis and progression.…”
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3152
Image 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.pdf
Published 2024“…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …”
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3153
Table 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.csv
Published 2024“…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …”
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3154
Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx
Published 2024“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”
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3155
Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg
Published 2024“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”
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3156
Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx
Published 2024“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”
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3157
Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx
Published 2024“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”
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3158
Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg
Published 2024“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”
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3159
Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg
Published 2024“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”
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3160
Table 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati...
Published 2025“…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …”