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17061
<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b>
Published 2025“…LOXL2 knockdown led to decreased tumor cell proliferation, enhanced apoptosis, and cell cycle arrest. …”
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17062
Video 3_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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17063
Supplementary Material for: A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma
Published 2025“…Although not curative, this therapeutic approach may play a significant role in the symptom management of these patients.…”
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17064
Data Sheet 2_Neuron-specific enolase in patients with acute and chronic schizophrenia, diversity of approaches: marker of neuronal death, neurodegeneration or neurodevelopmental th...
Published 2025“…</p>Results<p>The mean serum concentration of NSE in patients with schizophrenia was statistically significantly lower than in healthy controls. A weak negative correlation between NSE levels and the SANS score and a weak positive correlation between NSE levels and the SAPS score were found, but the results were not statistically significant. …”
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17065
Image 1_Effectiveness of nirsevimab immunization against RSV infection in preterm infants: a systematic review and meta-analysis.tif
Published 2025“…</p>Conclusion<p>Nirsevimab significantly decreases the risk of RSV-related infection in preterm infants and represents a valuable intervention for RSV prevention in this vulnerable population.…”
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17066
Figure 4 from OATP1B-type Transport Function Is a Determinant of Aromatase Inhibitor–Associated Arthralgia Susceptibility
Published 2025“…<p>OATP1B deficiency results in elevated AI plasma exposure and decreased liver accumulation. <b>A,</b> Pharmacokinetic profile of letrozole after a single oral dose of 10 mg/kg in wild-type and Oatp1a/1b<sup>(−/−)</sup> mice. …”
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17067
Table 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden...
Published 2025“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”
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17068
Image 5_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif
Published 2025“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”
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17069
Image 6_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.jpeg
Published 2025“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”
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17070
X-ray diffractometer and mineral composition.
Published 2025“…As the confining pressure increased, the ratio of tensile cracks in rock sample failure decreased, while the ratio of shear cracks increased. …”
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17071
Table 1_Contrasting interactions between photon spectra and temperature in cold-sensitive basil and cold-tolerant lettuce.docx
Published 2025“…The increased shoot expansion in lettuce decreased foliage coloration, but coloration was minimally altered in basil. …”
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17072
Image 1_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg
Published 2025“…After 3 h of sleep disruption, PG levels increased in the somatosensory cortex, but decreased in brainstem, and hypothalamus. After 6 h of sleep disruption, PG increased in the brainstem and olfactory bulb compared to control levels. …”
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17073
Composition and Detailed Characterization of Amino Acids, Peptides, Proteins, Fatty Acids, and Minerals of Tuna Trimming Fish Meal
Published 2025“…Tuna processing byproducts hold significant nutritional value, though their quality can vary based on species, size, environment, and processing level. …”
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17074
Image 4_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
Published 2025“…The age-standardized incidence rate (ASIR) experienced a decline of 1.07% from 1990 to 2021, while the age-standardized prevalence rate (ASPR) decreased by 0.95%. The incidence of EMT peaked among women aged 20–24 years, whereas mortality rates increased with advancing age. …”
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17075
Image 2_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg
Published 2025“…After 3 h of sleep disruption, PG levels increased in the somatosensory cortex, but decreased in brainstem, and hypothalamus. After 6 h of sleep disruption, PG increased in the brainstem and olfactory bulb compared to control levels. …”
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17076
Image 1_Integrative stress management for global workforce: music-based and exercise intervention for overseas employees.jpeg
Published 2025“…</p>Results<p>The experimental group demonstrated significant stress reduction (GARS scores decreased from 3.59 ± 0.71 to 2.68 ± 0.57, p < 0.001), with effects sustained at 6 months (p < 0.05). …”
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17077
Oral L-Arginine Treatment Attenuates<i>Cryptococcus neoformans</i>Extrapulmonary Dissemination and Disease Progression
Published 2025“…Oral L-arginine supplementation significantly reduced fungal burdens in the brain and spleen, suggesting its effectiveness in controlling cryptococcal dissemination from the lungs. …”
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17078
QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells
Published 2024“…</p> <p>Quality-by-design methodology led to optimization and systematic formulation of coloaded protamine-coated PLGA nanoparticles.</p> <p>Protamine decreased the initial burst release of the formulations.…”
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17079
Supplementary file 1_Characterization of the gut microbiota in people with different levels of obesity.docx
Published 2025“…</p>Results<p>In obese populations, the gut microbiome structure shifted significantly, with beneficial genera like Faecalibacterium, Roseburia, and Ruminococcus decreasing, and potentially harmful genera such as Blautia, Collinsella, and Streptococcus increasing. …”
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17080
Video (Efficacy of uterine manipulator in total abdominal hysterectomy)
Published 2025“…The manipulator group experienced a decreased postoperative hematocrit drop of 15.9 g/dl (p <0.001). …”