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significant factor » significant factors (Expand Search)
factor decrease » factors increases (Expand Search)
linear decrease » linear increase (Expand Search)
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Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx
Published 2025“…</p>Conclusion<p>This study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. Furthermore, renal BDNF expression decreased locally, predominantly originating from proximal tubule cells, macrophages, and podocytes, possibly epigenetically inhibited by the upregulation of lnc RNA Bdnf-as.…”
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Loss of MALS-1 function suppresses the mitochondrial and axon degeneration phenotypes that are caused by loss of RBM-26 function.
Published 2024“…Data are expressed as mean ± SEM from 3 biological replicates. Asterisks indicate statistically significant difference relative to wild type, Student’s <i>t</i> test (*<i>p</i> < 0.05). …”
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Overexpression of MALS-1 reduces mitochondria in the PLM axon and causes axon degeneration and axon overlap defects.
Published 2024“…For panels D and E, error bars represent the standard error of the proportion. Statistical significance in panel F was analyzed by Student’s <i>t</i> test, ***<i>p</i> < 0.0001 and error bars represent the standard error of mean. …”
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