Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment حسب Seán Fitzgerald (721911)

"…TRIM28 is a transcriptional co-repressor that regulates an abundance of genes through the KRAB domain family of transcription factors. We have previously shown that stromal expression of TRIM28 is a marker of disease relapse and poor survival in colorectal cancer. …"

Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN) حسب Btaiche, Imad

"…In contrast, TPN with lipid increased the expression of Fas and both the pro-apoptotic factor Bad and the anti-apoptotic factor Bcl-xl ( p <0.05). …"
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Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis حسب Ayman El-Menyar (440103)

"…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …"

Nurses’ work environment and intent to leave in Lebanese hospitals حسب Dimassi, Hani

"…Results The NWI-R subscale with the lowest mean score related to control. Younger nurses had lower scores on organizational support and career development. …"
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G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome حسب Francesco Casciello (18557613)

"…Hypoxia is an important factor known to initiate the metastatic cascade in cancer, activating cell motility and invasion by silencing cell adhesion genes. …"

Using primary healthcare facilities and patients’ expectations about triage system: Patients’ perspective from multisite Jordanian hospitals حسب Mohammad Minwer Alnaeem (19143733)

"…<h3>Background</h3><p dir="ltr"> Using primary healthcare facilities can decrease the tension and workload in emergency departments (EDs). …"

Association of microRNAs With Embryo Development and Fertilization in Women Undergoing Subfertility Treatments: A Pilot Study حسب Alexandra E. Butler (6189536)

"…Live birth rate was negatively associated with miR-335-3p, miR-100-5p, miR-497-5p, let-7d, and miR-574-3p (p < 0.05), but these were not significant when age was accounted for.However, with the exclusion of male factor infertility, all those miRNAs were no longer significant, though miR.150.5p emerged as significant (p = 0.042). …"

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer حسب Kodappully S. Siveen (4246150)

"…This transfer influences a number of immune-related pathways leading to activation/differentiation/expression of immune cells and modulation of the tumor microenvironment that plays a significant role in CRC progression, metastasis, and drug resistance. …"

Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis حسب Evdokia Varamenti (8154642)

"…Following more extended training periods, GSH showed moderate increases (ES 1.131; 95% CI 0.350 to 1.913;<i>Z</i>= 2.839,<i>p</i>= 0.005) while TBARS displayed a small decrease (ES 0.568; 95% CI − 0.062 to 1.197;<i>Z</i>= 1.768,<i>p</i>= 0.077). …"

The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells حسب Maram Hasan (6672440)

"…At the protein expression level, our results demonstrated that MSCs-CM (50%) enhanced the expression of the detoxifying NQO1in MGO-injured cells.…"

Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie حسب Echtay, Akram

"…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …"
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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways حسب Hadeel Kheraldine (14231609)

"…PAMAMs can modulate gene expression and interfere with transactivation of the human epidermal growth factor receptor family members (HER1-4). …"

Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways حسب Hadeel, Kheraldine

"…PAMAMs can modulate gene expression and interfere with transactivation of the human epidermal growth factor receptor family members (HER1-4). …"
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Preparation of Mesoporous/Microporous MnCo₂O₄ and Nanocubic MnCr₂O₄ Using a Single Step Solution Combustion Synthesis for Bifunction Oxy... حسب Anchu Ashok (14152020)

"…Chronoamperometric (CA) runs for 24 h shows excellent stability of MnCo₂O₄ without any significant decrease in the current or potential value in ORR and OER. …"

Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population حسب Ghassibe-Sabbagh, Michella

"…People with T2DM showed a significant decrease in HDL-C levels. A strong correlation of overall hyperlipidemia with the diabetes affection status was shown (p < 0.0001). …"
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Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model حسب Wiem Elloumi (17148337)

"…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …"

Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults حسب Khaddaj, Rashel

"…Furthermore, the change between both groups was significantly different (-7.61 ±4.03 in the Vitamin D group, -3.50±1.54 in the control group; p=<0.001) Conclusion: The present study shows thata 50.000 IU/week dose of vitamin D supplementation for 3 months was enough to increase vitamin D levels beyond sufficient and decrease depression symptoms in Saudi Arabian Adults. …"
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IS security menace حسب Balozian, Puzant

"…Modern organizations face significant information security violations from inside the organizations to which they respond with various managerial techniques. …"
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Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study حسب M. S Ajimsha (21250760)

"…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. …"

Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study حسب Zeana, Samir AlKudsi

"…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …"
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