Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx حسب Lina Ouologuem (22489549)

"…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…"

Dynamic changes in mRNA stability. حسب Shiqi Luo (3829597)

"…<b>(D)</b> GO analysis showing the enriched biological processes for mRNAs with increased (left) or decreased (right) stability in 6 hours of LPS treatment. …"

Supplementary file 1_Investigating the feasibility of machine learning to guide personalized red blood cell (RBC) transfusion: analyzing the heterogeneity of RBC transfusion in sep... حسب Penglei Yang (8090156)

"…The Kaplan-Meier curves and the log-rank test demonstrated that the RBC transfusion decreased the survival of patients in Quantile1 (p < 0.001) and Quantile2 (p = 0.011) but increased the survival of patients in Quantile4 (p < 0.001).…"

Image_1_Study of epirubicin sustained–release chemoablation in tumor suppression and tumor microenvironment remodeling.jpeg حسب Liangliang Meng (9500122)

"…On day 4 after local injection of the EPI gel, the expression of PD-L1 in abscopal tumors was upregulated, while the expression of PD-L1 in bilateral tumors in mice was significantly reduced after anti-PD-L1 treatment. The proportion of CD3⁺CD8⁺PD-1⁺ cells in the tumor and circulating blood in the EPI-GEL/PD-L1 group was decreased compared with that in the EPI-GEL (single injection of epirubicin) group.…"

Data Sheet 1_IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection.pdf حسب Rafaella Oliveira dos Santos (21710366)

"…Introduction<p>Malaria remains a significant public health challenge in Brazil, where Plasmodium vivax (P. vivax) is the predominant species. …"

Table 1_Associated effects of lipopolysaccharide, oleic acid, and lung injury ventilator-induced in developing a model of moderate acute respiratory distress syndrome in New Zealan... حسب Xingyu Tian (17791894)

"…The LOV group showed the most severe lung injury, significantly decreasing MAP and Cdyn. Pathological and ultrasound scores were considerably higher in the LOV group compared to the OM and LOM groups (p < 0.05). …"

Table 1_Comparison of preoperative education by artificial intelligence versus traditional physicians in perioperative management of urolithiasis surgery: a prospective single-blin... حسب Hui Zhang (7197)

"…</p>Results<p>All participants completed the study. Anxiety decreased significantly after intervention in all groups (p < 0.05). …"

Table 1_Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China.do... حسب Hongxiang Ji (11235519)

"…Both mean SBP and DBP levels significantly decreased in the HI group compared to control group at each follow-up visit with the between group difference of −4.63 mm Hg (95% CI, −6.51 to −2.74) at week 8, −6.69 mm Hg (95% CI, −8.54 to −4.85) at week 16, −7.81 mm Hg (95% CI, −9.57 to −6.04) at week 24 for SBP, and −1.83 mm Hg (95% CI, −3.21 to −0.45) at week 8, −2.57 mm Hg (95% CI, −3.97 to −1.17) at week 16, −2.89 mm Hg (95% CI, −4.24 to −1.54) at week 24 for DBP. …"

Supplementary file 1_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma... حسب Huijie Lai (22696685)

"…Conversely, PTEN expression was found to be decreased. Additionally, autophagy-related protein levels were diminished while anti-apoptotic protein expression was markedly elevated (P < 0.01). …"

DESeq output data for all comparisons. حسب Hilary T. Brewis (11798006)

"…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …"

Data Sheet 1_Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders.docx حسب Juanjuan Fang (413481)

"…After full adjustment for covariates, mLE8 exhibited a significant mediating role in the associations of both DI-GM (14.46% mediated effect, p < 0.001) and DI-GM beneficial (12.99% mediated effect, p < 0.001) with sleep disorders. …"

Supplementary file 2_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma... حسب Huijie Lai (22696685)

"…Conversely, PTEN expression was found to be decreased. Additionally, autophagy-related protein levels were diminished while anti-apoptotic protein expression was markedly elevated (P < 0.01). …"

Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... حسب Yuhua Jiang (10300159)

"…PSCK9 inhibitors and potent statins significantly reduced LDL-C levels from baseline vs. placebo regardless of background therapy. …"

 'Plan-B':  Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes حسب marion delphin (13249479)

"…One-third of respondents reported already experiencing significant impact from funding changes, while over two-thirds expressed high concerns about future effects. …"

Table 1_Yeast culture improves growth, antioxidant status, immunity, and gut microbiota homeostasis in preweaning Holstein calves.docx حسب Xueqiang Li (614522)

"…Serum levels of total antioxidant capacity (T-AOC), total superoxide dismutase (T-SOD), and glutathione peroxidase (GSH-Px) were significantly elevated, while malondialdehyde (MDA) content was significantly decreased (p < 0.05), indicating improved antioxidant status. …"

Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

"…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…"

Image 1_Effect of midwife-led continuity of care combined with individualized breast management on postpartum recovery and lactation function in women undergoing cesarean section.t... حسب Hua Cai (15034)

"…Although the incidence of pelvic floor dysfunction showed a decreasing trend in the intervention group, this difference was not statistically significant (p > 0.05). …"

Table 1_The effect of Traumeel LT ad us. vet. on the perioperative inflammatory response after castration of stallions: a prospective, randomized, double-blinded study.docx حسب Julia Laves (19779357)

"…All stallions had the highest pain summary score 8 hours after surgery, with decreasing values thereafter. The pain scores were not statistically different at any time point. …"

Data Sheet 1_Unveiling causal immune cell–gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses.docx حسب Hui Zhang (7197)

"…NCAM1 also exhibited a significant methylation-level association with disease.…"

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

"…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…"