Search alternatives:
shape decrease » shape increases (Expand Search), small decrease (Expand Search), showed decreased (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
gap decrease » a decrease (Expand Search), gain decreased (Expand Search), mean decrease (Expand Search)
shape decrease » shape increases (Expand Search), small decrease (Expand Search), showed decreased (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
gap decrease » a decrease (Expand Search), gain decreased (Expand Search), mean decrease (Expand Search)
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Juvenile demyelination impairs the maturation of PV interneurons in the PFC.
Published 2025“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …”
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464
PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination.
Published 2025“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …”
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465
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Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties.
Published 2025“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …”
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468
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Juvenile demyelination induces a loss of functional autapses.
Published 2025“…Cuprizone-treated mice show a significant decrease in the percentage of cells showing an autaptic response (<i>Fisher’s exact test; *p = 0.0173</i>). …”
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470
AUT00201 (1 µM) can rescue AP width in cuprizone mice.
Published 2025“…In the responsive cells from cuprizone mice (red) a significant increase in PV interneuron firing frequency at lower current steps (gray) was observed (<i>group x current two-way repeated measures: n = 8 cells from 4 mice: p = 0.05287; AUT00201 effect: F(1,60) = 5.050, *p = 0.0457. …”
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471
Autapses play a crucial role in PV interneuron’s sustained firing at high frequencies.
Published 2025“…Average action potential (AP) frequency in response to 0−650 pA current steps illustrating a significant increase in PV interneuron firing frequency at low-current steps in control cells without autapses (gray) compared to control cells with autapses (black). …”
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472
Comparison between juvenile and adult demyelination.
Published 2025“…Juvenile demyelination leads to impairment in PV interneuron maturation whereas adult demyelination induces a decrease in the excitability of PV interneurons. Summary data showing the averaged (± s.e.m) of the following intrinsic properties: (A) Resting membrane potential (RMP) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: *p < 0.05, **p < 0.01, ****p < 0.0001</i>), (B) Input resistance (IR) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0024, post-hoc LSD test: *p < 0.05, **p < 0.01, ***p < 0.001</i>), (C) Sag (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0083, post-hoc LSD test: *p < 0.05, **p < 0.01</i>), (D) Rheobase (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, p = 0.1230, post-hoc LSD test: *p < 0.05</i>) and (E) Action potential (AP) threshold (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, *p = 0.0452, post-hoc LSD test: *p < 0.05</i>), (F) AP half-width (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0058, post-hoc LSD test: **p < 0.01</i>), (G) Average action potential (AP) frequency in response to 0–650 pA current steps illustrating no significant change in S1 PV interneuron firing frequency following juvenile demyelination (<i>group x current two-way repeated measures: n = 36,30,19,24 cells from 9/8/8/6 mice per group: F(39,1,291) = 2.487, ****p < 0.0001</i>) and (H) Maximum firing frequency per group (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: ***p < 0.001, ****p < 0.0001</i>). …”
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473
Multiscale QM/MM Simulations Identify the Roles of Asp239 and 1‑OH···Nucleophile in Transition State Stabilization in Arabidopsis thaliana Cell-Wall Invertase 1
Published 2025“…The glycosylation and deglycosylation steps were considered in both wild type and mutants. …”
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474
Data Sheet 1_Diversity, functionality, and stability: shaping ecosystem multifunctionality in the successional sequences of alpine meadows and alpine steppes on the Qinghai-Tibet P...
Published 2025“…Surprisingly, community stability also significantly influences ecosystem multifunctionality—a factor rarely highlighted in previous studies. …”
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475
Sociodemographic Characteristics of Sample 2.
Published 2025“…We also found that the mean agreement with the IB-DE subscale decreased after the pandemic. In a separate third sample (N<sub>S3</sub> = 39, 19 women, M<sub>age</sub> = 23.72), we observed an inverse U-shape relationship between moral behavior related to quarantine requirements and the IH-DE subscale, as measured during the peak pandemic restrictions in late 2020. …”
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476
English and German versions of OUS.
Published 2025“…We also found that the mean agreement with the IB-DE subscale decreased after the pandemic. In a separate third sample (N<sub>S3</sub> = 39, 19 women, M<sub>age</sub> = 23.72), we observed an inverse U-shape relationship between moral behavior related to quarantine requirements and the IH-DE subscale, as measured during the peak pandemic restrictions in late 2020. …”
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477
Magnetic Fields Generated by Directed Ionic Flow
Published 2024“…Furthermore, it increases with the number of effective coils and decreases with larger conduit sizes, demonstrating the significant impact of conduit shape on the generated magnetic field. …”
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478
Magnetic Fields Generated by Directed Ionic Flow
Published 2024“…Furthermore, it increases with the number of effective coils and decreases with larger conduit sizes, demonstrating the significant impact of conduit shape on the generated magnetic field. …”
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Co–Fe–Mo Phosphides’ Triphasic Heterostructure Loaded on Nitrogen-Doped Carbon Nanofibers by Electrospinning as Efficient Bifunctional Electrocatalysts for Overall Water Splitting...
Published 2025“…The rational design of efficient and stable bifunctional electrocatalysts for the hydrogen evolution reactions (HER) and oxygen evolution reactions (OER) poses a significant challenge in realizing environmentally friendly hydrogen production through electrocatalytic water splitting. …”