Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf حسب Shuangmei Zhang (1807303)

"…Traditional treatments are often accompanied by side effects and lack specificity. Recent studies have found that Th17 cells and the inflammatory factor IL-17, which they secrete, play a key role in the pathogenesis of MG and have become potential therapeutic targets. …"

Table 3_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.xlsx حسب Yue Song (162328)

"…Nonsteroidal anti-inflammatory drugs (NSAIDs) and hormonal contraceptives are the first-line treatments for dysmenorrhea; however, they have significant side effects. Electroacupuncture, as a non-invasive and effective therapeutic method, is widely used as a complementary and alternative treatment, although its mechanism of action remains unclear.…"

Table 1_Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.xlsx حسب Yue Song (162328)

"…Nonsteroidal anti-inflammatory drugs (NSAIDs) and hormonal contraceptives are the first-line treatments for dysmenorrhea; however, they have significant side effects. Electroacupuncture, as a non-invasive and effective therapeutic method, is widely used as a complementary and alternative treatment, although its mechanism of action remains unclear.…"

Table 1_Effect of simulated acidification on soil properties and plant nutrient uptake of eggplant in greenhouse.docx حسب Tianqi Wang (4093009)

"…Among the available nutrients, only potassium levels did not exhibit significant variation across treatments. However, the levels of macro elements in the soil consistently decreased, while the concentrations of trace elements (Fe, Cu, Zn) increased with rising acidity; conversely, the levels of other trace elements (B, Mo, Mn) decreased. …"

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... حسب Jing Lu (120666)

"…However, there is still a knowledge gap regarding the relationship between SI and mortality in the CVD population.…"

Azole drugs have differential efficacy in varied models of immunosuppression in larval zebrafish hosts حسب Kevin E. Ayala (21979064)

"…<p>Fungal infections are an increasing cause of mortality in immunosuppressed human patients, and antifungal drug treatments are still ineffective in a significant percentage of cases. A gap in our understanding of antifungal drug treatment is whether different drugs have differential efficacy in hosts that are experiencing different forms of immunosuppression.…"

raw data حسب Boya Gao (21686150)

"…Bacterial abundance under moderate and extreme disturbances was significantly lower than that in the control, whereas fungal abundance was significantly higher under extreme disturbance. …"

Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study حسب Klaus G. Parhofer (12280424)

"…This suggests an underutilisation of available treatments, highlighting a gap in the management of high CV risk patients.</p>…"

Table 1_Trends in the burden of chronic diseases attributable to diet-related risk factors from 1990 to 2021 and the global projections through 2030: a population-based study.docx حسب Huan Ma (713125)

"…Background<p>The global burden of diet-related chronic diseases and their future projections remain unclear. To address this gap, we present the latest data on deaths and disability-adjusted life years attributable to dietary factors from 1990 to 2021, focusing on noncommunicable diseases worldwide. …"

Data Sheet 1_A comparative analysis of nutritional content changes in six Chinese cuisines prepared using industrial versus traditional hand-cooked modes.docx حسب Xuan Wang (55634)

"…An inter-group t-test indicated no significant differences in nutrient content changes between the two cooking modes (p > 0.05), except for vitamin B6 retention, which was significantly lower in traditional hand-cooked modes compared to industrial modes (p < 0.05).…"

Data Sheet 1_The effect of establishment method and shade zones within solar arrays on pasture production in agrivoltaics production system.docx حسب Azad Dazaea (22173454)

"…Pastures were harvested periodically over two growing seasons from four 1 m-wide zones (A to D) within the alleys between arrays, with shading intensity decreasing from zone A (south side, under the panels) to zone D (north side of the alley). …"

Table 1_Loneliness and mental burden among German medical students during the fading COVID-19 pandemic: a mixed-methods approach.docx حسب Marvik Leich (20930363)

"…While the pandemic-related burden on students' study motivation lessened, issues related to exam preparation and lack of study organization through the faculty increased, varying significantly depending on students' study year.</p>Conclusion<p>Our data suggest that loneliness among German medical students decreased in the late stages of the COVID-19 pandemic. …"

Image 2_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Table 3_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.xlsx حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 10_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 7_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Table 5_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.docx حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 4_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"

Image 5_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif حسب Han Chu (7417343)

"…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…"