STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS by AL-SADEQ, DUAA WALID

“…This reduced activity is consistent with both in vitro and in silico evidence, which indicates that the studied CBS mutations, except p.K72I, significantly decrease the overall protein's stability, which may represent the underlying cause of their pathogenicity. …”
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy by Laiche, Djouhri

“…We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …”
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OIL PRICE UNCERTAINTY AND RENEWABLE ENERGY INNOVATION: AN INTERNATIONAL EVIDENCE by AL-SHAMMARI, AMEERA

“…Climate change is a significant global issue that is closely tied to efforts to decrease energy usage and increase energy efficiency. …”
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A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis by Tricarico, Paola Maura

“…Since several transcriptome studies have shown a significantly decreased expression of DCD in HS skin, we hypothesised that the identified frameshift insertion was a loss-of-function mutation that might be associated with HS susceptibility in this family. …”
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Unveiling into Genetic Architecture of Transgenerational Stress Memory via Promoting Drought Tolerance in Barley by Alqudah, Ahmad M.

“…The decrease in G% was 19% and the decrease in GP was 67%. …”
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Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre... by Alatawi, Aishah

“…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …”
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High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury by Stanley, Ibeh

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Wind energy potential along the onshore and offshore Qatar by Mohammed, Aboobacker Valliyil

“…Compared to the earlier studies, in this work, we have assessed the wind power at inland and o?…”
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Ocean Acidification and Carbonate System Geochemistry in the Arabian Gulf by Al-Thani, Jassem A.

“…We calculated the nitrate corrected and salinity normalized tracer, Alk*. …”
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Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischemia. by Oliva-Olivera, Wilfredo

“…Our aim was to examine the neovascular potential under hypoxic conditions of ASCs-derived from thymic (thymASCs) and subcutaneous (subASCs) AT from 39 subjects with and without type 2 diabetes mellitus (T2DM) and of different ages who were undergoing coronary bypass surgery (CBS). We confirmed a significant decrease in the percentage of CD34+ CD31- CD45- subASCs in the cell yield of subASCs and in the survival of cultured endothelial cells in the medium conditioned by the hypox-subASCs with increasing patient age, which was not observed in thymASCs. …”
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model by Da’as, Sahar Isa

“…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …”
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SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle by Koltai, Erika

“…Furthermore, increased levels of K63 and muscle RING finger 2 (MuRF2) protein could also be important enhancers of muscle mass. We report here that the levels of miR1 and miR133a decrease in hypertrophy and negatively correlate with muscle mass, SIRT1 and Nampt levels. …”
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Automatic Sleep Arousal Detection Using State Distance Analysis in Phase Space by Zabihi M.

“…We first show how the states distance matrices of a complex system can be reconstructed to decrease the effect of false neighbors. …”
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Corporate governance and cost of debt financing: Empirical evidence from Canada by Ghouma, Hatem

“…In addition to the Board Composition and the Disclosure sub-indexes, we also find a significant negative relationship between shareholder rights sub-index and the cost of debt for issuers headquartered in Quebec. …”
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Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling by Ghantous, Crystal M.

“…Stretching the RPV also significantly increased ROS generation after 1 hour, whereas APN significantly decreased mechanical stretch-induced ROS production. …”
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THE ASSOCIATION BETWEEN SOFT DRINK CONSUMPTION AND BONE MINERAL DENSITY AMONG QATARI WOMEN: ANALYSIS OF QATAR BIOBANK DATA by HAMID, AAMNA MOHAMED IDREES ALI

“…Reports from these studies presented conflicting findings. Some suggesting significant decreases in BMD levels due to soft drink consumption, while others find null associations. …”
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OIL PRICE SHOCKS AND STOCK PRICE INFORMATIVENESS: EVIDENCE FROM GCC FIRMS by ABOHAMIDA, ALA A.

“…We also show that supply (demand) shocks decrease (increase) stock price informativeness. …”
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Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals. by Anwardeen, Najeha

“…The significant decrease in NT-proBNP observed in individuals with insulin resistance may be attributed to a direct or indirect enhancement in glutathione production, which is regarded as a compensatory mechanism against oxidative stress. …”
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis by Nazmul, Islam

“…Meta-regression showed a significant decrease in SSI incidence in HICs. Maternal factors, procedural aspects, and care quality were associated with SSI. …”
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