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61
Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients
Published 2019“…We also investigated correlations between the levels of different CD4<sup>+</sup> T cell subsets and the clinicopathologic features including disease stage and tumor budding. We found a significant increase in the levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> T cells, which represent potentially highly immunosuppressive Tregs, in the CRC TME. …”
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62
Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
Published 2019“…The BRMUS was used to evaluate the emotional states of vigilance task before and after using the audio stimulation. BRMUS factors, such as fatigue, depression, and anger, significantly decrease in the enhancement group compared to vigilance group. …”
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63
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”
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64
OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo...
Published 2023“…<p dir="ltr">This study reveals a significant connection between prenatal bonding or attachment during pregnancy and various factors such as maternal age, anxiety, and stress, including those attributed to specific events like the COVID-19 pandemic. …”
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65
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…By collecting the opinions of managers and executives working in the risk management sector, these factors were appraised and classified. Furthermore, different variables were analysed to find that some of them may be more significant than others. …”
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66
Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation
Published 2019“…Performing a targeted association analysis for the significant T21-associated CpG sites in the AgeCoDe cohort, we found that 9 showed significant methylation differences related to AD dementia, including one in the ADAM10 gene. …”
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67
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
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68
Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism
Published 2023“…<p dir="ltr">Children from old fathers carry an increased risk for autism spectrum (ASD) and other neurodevelopmental disorders, which may at least partially be mediated by paternal age effects on the sperm epigenome. …”
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69
Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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70
Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
Published 2025“…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. …”
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71
Tipping the Balance: Vitamin D Inadequacy in Children Impacts the Major Gut Bacterial Phyla
Published 2022“…<div><p>Vitamin D inadequacy appears to be on the rise globally, and it has been linked to an increased risk of osteoporosis, as well as metabolic, cardiovascular, and autoimmune diseases. …”
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72
Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways
Published 2022“…Treatment of rats with Pb for three consecutive days significantly increased the accumulation of Pb in lung tissues causing severe interstitial inflammation. …”
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73
Phenotypic and Genotypic Characterization of Candida parapsilosis complex isolates from a Lebanese Hospital
Published 2023“…Our results showed that resistant isolates had no increased ergosterol content, or chitin deposition, no significant difference in virulence, but exhibited an increase in biofilm content compared with sensitive isolates. …”
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74
Characterizing the dynamics of climate and native desert plants in Qatar
Published 2024“…Additionally, vegetation cover varied between protected sites, indicating the complexity of arid lands influenced by factors like topography and soil type. These findings suggest a continued decrease in vegetation coverage, leading to more drought seasons and impacting water and food security. …”
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75
Optimizing the Cleaning Frequency of Solar Photovoltaic (PV) systems Using Numerical Analysis
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doctoralThesis -
76
Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
Published 2024“…WD has been shown to impair cognitive function, decrease the brain's capacity to compensate for insult by affecting recovery as well as induce metabolic syndrome (MetS) which may be a risk factor for poor TBI prognosis. …”
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Inappropriate Medication Use in Elderly Lebanese Outpatients
Published 2006“…Statistical analyses were performed to estimate the prevalence of inappropriate medication use and to identify potentially predictive factors of such use arising from patients’ sociodemographic characteristics, health factors and drug regimen intake. …”
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Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
Published 2014“…People with T2DM showed a significant decrease in HDL-C levels. A strong correlation of overall hyperlipidemia with the diabetes affection status was shown (p < 0.0001). …”
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<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
Published 2022“…Interestingly, apoptosis was mediated by a significant loss of mutant p53 protein, and increased Bax/Bcl2 ratio. …”
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80
Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…On multivariate analysis, factors that significantly predicted increased red cell transfusion rates were female sex, pre-operative hematocrit <30%, platelet count <100,000/mm3, simultaneous resection of other organs, major hepatic resection, use of the Pringle maneuver, and tumors >10 cm. …”
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