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1
Detection of statistically significant network changes in complex biological networks
منشور في 2017"…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …"
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2
Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene
منشور في 2004"…The GG genotype was also significantly higher among patients (12.6%) than in controls (4.2%). χ2 analysis and family-based association studies were performed and suggested the association of CTLA4 exon 1 G polymorphism with T1D (p = 0.0229). …"
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3
Efficient experimental design for uncertainty reduction in gene regulatory networks
منشور في 2015"…Gene regulatory networks often contain a significant amount of uncertainty. …"
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Correlation of Immunological and Histopathological Features with Gene Expression-Based Classifiers in Colon Cancer Patients
منشور في 2022"…<div><p>The purpose of this study was to evaluate the association between four distinct histopathological features: (1) tumor infiltrating lymphocytes, (2) mucinous differentiation, (3) tumor-stroma ratio, plus (4) tumor budding and two gene expression-based classifiers—(1) consensus molecular subtypes (CMS) plus (2) colorectal cancer intrinsic subtypes (CRIS). …"
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6
Wastewater-based epidemiology for tracking bacterial diversity and antibiotic resistance in COVID-19 isolation hospitals in Qatar
منشور في 2023"…BackgroundHospitals are hotspots for antimicrobial resistance genes (ARGs), and play a significant role in their emergence and spread. …"
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7
Board changes and CEO turnover
منشور في 2014"…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …"
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8
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"
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9
The combinatory effects of diet and exercise on BDNF gene expression
منشور في 2017"…Results showed that supplementation with 1.5% leucine significantly induced BDNF in the brain, and this effect was additive with exercise as well. …"
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10
Variational Auto Encoder Approach To Find Deferentially Expressed Genes
منشور في 2022"…The proposed method makes use of cluster distribution on every latent space and merged weights in the decoder to assign genes to a cluster. My results discovered new sets of genes that were not shown using state-of-the-art techniques and can properly rank the top genes based on their significance in making clustering.…"
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11
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"
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12
Vocal Changes in Patients With Polycystic Ovary Syndrome
منشور في 2011"…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …"
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13
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
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14
Gene-specific machine learning model to predict the pathogenicity of BRCA2 variants
منشور في 2022"…We trained the model on 80% of the expert reviewed variants by the Evidence-Based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) consortium and tested its performance on the remaining 20%, as well as on an independent set of variants of uncertain significance with experimentally determined functional scores.…"
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15
Essays on the effect of excess compensation and governance changes on firm value
منشور في 2012"…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …"
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masterThesis -
16
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17
Organic micropollutants in aerobic and anaerobic membrane bioreactors: Changes in microbial communities and gene expression
منشور في 2016"…Microbial community dynamics, gene expression levels, and antibiotic resistance genes were analyzed using molecular-based approaches. …"
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article -
18
Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
منشور في 2019"…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …"
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19
The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
منشور في 2020"…This study aimed to identify upregulated genes and significant pathways involved in CLBC. …"
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20
The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
منشور في 2020"…This study aimed to identify upregulated genes and significant pathways involved in CLBC. …"