Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…Prolonged acidosis, as it occurs during ischemic stroke, induces neuronal death via acid-sensing ion channel 1a (ASIC1a). Concomitantly, it desensitizes ASIC1a, highlighting the pathophysiological significance of modulators of ASIC1a acid sensitivity. …”

Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…Prolonged acidosis, as it occurs during ischemic stroke, induces neuronal death via acid-sensing ion channel 1a (ASIC1a). Concomitantly, it desensitizes ASIC1a, highlighting the pathophysiological significance of modulators of ASIC1a acid sensitivity. …”

Consort statement showing participants enrollment, intervention allocation, follow-up, and data analysis throughout the study. by Habiba I. Ali (10451382)

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Deidentified skills for change dataset. by Habiba I. Ali (10451382)

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Physical activity levels and sitting times of study participants (n = 382). by Habiba I. Ali (10451382)

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Micronutrient intakes of study participants (n = 382). by Habiba I. Ali (10451382)

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Baseline characteristic of study participants (n = 382). by Habiba I. Ali (10451382)

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First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

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First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

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Decreased hypotaurine levels within cells lacking the ADO gene in U251 cells. by Hong Tian (169626)

Comparative analysis of SMI in two groups. by Ekaterina Khristenko (17847064)

“…In patients with reduced BMI sarcopenia was found in all cases (100%). Statistically significant difference of SMI between two groups was revealed for both sexes (p = 0,0001), with no significant difference between groups in BMI. …”

Integrin expression decreased in treated tumors. by Anthony B. Eason (6294305)

Preparatory neuronal activity in ALM is decreased, but remains significant in quiet trials devoid of movements. by Vahid Esmaeili (12700352)

Total tau levels are significantly decreased in the healthy older brains compared to the younger brains. by Shreyasi Chatterjee (3531506)

Significant decrease of the coiled-coil score in the double proline-substituted CAHS3 mutant. by Akihiro Tanaka (342394)

BLyS^-/- significantly decreased IgM and IgG secreting cells. by Natalie M. Bath (6316517)

Top 20 genes with significantly decreased abundance in Aco^R cells. by Pieter C. Steketee (10024552)

CRISPRi knockdown of RgaR-dependent genes specifically and significantly decreases their transcript levels. by Adrianne N. Edwards (5646344)

Plasma cells, but not memory B cells, were significantly decreased with APRIL/BLyS blockade. by Natalie M. Bath (6316517)

The effect of β-blocker treatment on renin (A) and aldosterone-to-renin ratio (B). by Ningning Wang (560944)

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